Effects of plasma membrane cholesterol level and cytoskeleton F-actin on cell protrusion mechanics. [PDF]
, 2013 Protrusions are deformations that form at the surface of living cells during biological activities such as cell migration. Using combined optical tweezers and fluorescent microscopy, we quantified the mechanical properties of protrusions in adherent ...
Anvari, Bahman +3 more
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Getting cells into shape by calcium-dependent actin cross-linking proteins
Frontiers in Cell and Developmental Biology, 2023 The actin cytoskeleton represents a highly dynamic filament system providing cell structure and mechanical forces to drive a variety of cellular processes.
Franziska Lehne, Sven Bogdan
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IEEE Access, 2022 Actin cytoskeleton morphology is able to affect and reflect the cellular mechanical properties. However, due to the lack of efficient approaches to quantifying actin cytoskeleton and mechanical properties, the study of mechanotransduction dynamics is ...
Yi Liu +3 more
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Regulation of the Actin Cytoskeleton in Podocytes
Cells, 2020 Podocytes are an integral part of the glomerular filtration barrier, a structure that prevents filtration of large proteins and macromolecules into the urine.
Judith Blaine, James Dylewski
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Role of actin cytoskeleton in the organization and function of ionotropic glutamate receptors
Current Research in Structural Biology, 2021 Neural networks with precise connection are compulsory for learning and memory. Various cellular events occur during the genesis of dendritic spines to their maturation, synapse formation, stabilization of the synapse, and proper signal transmission. The
Priyanka Dutta +3 more
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Actin Remodeling Defects Leading to Autoinflammation and Immune Dysregulation
Frontiers in Immunology, 2021 A growing number of monogenic immune-mediated diseases have been related to genes involved in pathways of actin cytoskeleton remodeling. Increasing evidences associate cytoskeleton defects to autoinflammatory diseases and primary immunodeficiencies.
Riccardo Papa +3 more
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LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton
Frontiers in Cell and Developmental Biology, 2021 LUZP1 is a centrosomal and actin cytoskeleton-localizing protein that regulates both ciliogenesis and actin filament bundling. As the cytoskeleton and cilia are implicated in metastasis and tumor suppression, we examined roles for LUZP1 in the context of
Laura Bozal-Basterra +12 more
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Phosphatidylinositol (4,5)-bisphosphate turnover by INP51 regulates the cell wall integrity pathway in "Saccharomyces cerevisiae" [PDF]
, 2004 Signal transduction pathways are important for the cell to transduce external or internal stimuli where second messengers play an important role as mediators of the stimuli. One important group of second messengers are the phosphoinositide family present
Morales-Johansson, Helena
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Actin cytoskeleton-dependent regulation of corticotropin-releasing factor receptor heteromers [PDF]
, 2017 Stress responses are highly nuanced and variable, but how this diversity is achieved by modulating receptor function is largely unknown. Corticotropin-releasing factor receptors (CRFRs), class B G protein–coupled receptors, are pivotal in mediating ...
Bhargava, Aditi +7 more
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Actin Cytoskeleton Affects Schwann Cell Migration and Peripheral Nerve Regeneration
Frontiers in Physiology, 2018 Actin cytoskeleton regulates many essential biological functions, including cellular development, shape, polarity, and motility. The organization of actin cytoskeleton has also been associated with numerous physiological and pathological conditions, for ...
Yaxian Wang +3 more
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