Results 11 to 20 of about 297,755 (331)

Phagocytosis and the actin cytoskeleton [PDF]

open access: yesJournal of Cell Science, 2001
ABSTRACT The process of engulfing a foreign particle – phagocytosis – is of fundamental importance for a wide diversity of organisms. From simple unicellular organisms that use phagocytosis to obtain their next meal, to complex metazoans in which phagocytic cells represent an essential branch of the immune system, evolution has armed ...
Laura M. Machesky, Robin C. May
openaire   +3 more sources

Getting cells into shape by calcium-dependent actin cross-linking proteins

open access: yesFrontiers in Cell and Developmental Biology, 2023
The actin cytoskeleton represents a highly dynamic filament system providing cell structure and mechanical forces to drive a variety of cellular processes.
Franziska Lehne, Sven Bogdan
doaj   +1 more source

Effects of plasma membrane cholesterol level and cytoskeleton F-actin on cell protrusion mechanics. [PDF]

open access: yes, 2013
Protrusions are deformations that form at the surface of living cells during biological activities such as cell migration. Using combined optical tweezers and fluorescent microscopy, we quantified the mechanical properties of protrusions in adherent ...
Anvari, Bahman   +3 more
core   +16 more sources

Cellular Actin Cytoskeleton Morphology Identification for Mechanical Characterization Using Deep Learning

open access: yesIEEE Access, 2022
Actin cytoskeleton morphology is able to affect and reflect the cellular mechanical properties. However, due to the lack of efficient approaches to quantifying actin cytoskeleton and mechanical properties, the study of mechanotransduction dynamics is ...
Yi Liu   +3 more
doaj   +1 more source

Actin Remodeling Defects Leading to Autoinflammation and Immune Dysregulation

open access: yesFrontiers in Immunology, 2021
A growing number of monogenic immune-mediated diseases have been related to genes involved in pathways of actin cytoskeleton remodeling. Increasing evidences associate cytoskeleton defects to autoinflammatory diseases and primary immunodeficiencies.
Riccardo Papa   +3 more
doaj   +1 more source

Dynamic reorganization of the actin cytoskeleton [PDF]

open access: yesF1000Research, 2015
Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structures are highly dynamic. Indeed, they assemble, grow, and
Manuel Théry   +5 more
openaire   +6 more sources

LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton

open access: yesFrontiers in Cell and Developmental Biology, 2021
LUZP1 is a centrosomal and actin cytoskeleton-localizing protein that regulates both ciliogenesis and actin filament bundling. As the cytoskeleton and cilia are implicated in metastasis and tumor suppression, we examined roles for LUZP1 in the context of
Laura Bozal-Basterra   +12 more
doaj   +1 more source

Quantitative Investigation of the Link between Actin Cytoskeleton Dynamics and Cellular Behavior

open access: yesMicromachines, 2022
Actin cytoskeleton reorganization, which is governed by actin-associated proteins, has a close relationship with the change of cell biological behavior. However, a perceived understanding of how actin mechanical property links to cell biological property
Ying Li, Xiaoru Zhuang, Fuzhou Niu
doaj   +1 more source

Actin cytoskeleton-dependent regulation of corticotropin-releasing factor receptor heteromers [PDF]

open access: yes, 2017
Stress responses are highly nuanced and variable, but how this diversity is achieved by modulating receptor function is largely unknown. Corticotropin-releasing factor receptors (CRFRs), class B G protein–coupled receptors, are pivotal in mediating ...
Bhargava, Aditi   +7 more
core   +1 more source

Actin Cytoskeleton Affects Schwann Cell Migration and Peripheral Nerve Regeneration

open access: yesFrontiers in Physiology, 2018
Actin cytoskeleton regulates many essential biological functions, including cellular development, shape, polarity, and motility. The organization of actin cytoskeleton has also been associated with numerous physiological and pathological conditions, for ...
Yaxian Wang   +3 more
doaj   +1 more source

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