Coupling biochemistry and mechanics in cell adhesion: a model for inhomogeneous stress fiber contraction [PDF]
New J. Phys., 9:425, 2007, 2007 Biochemistry and mechanics are closely coupled in cell adhesion. At sites of cell-matrix adhesion, mechanical force triggers signaling through the Rho-pathway, which leads to structural reinforcement and increased contractility in the actin cytoskeleton.
Achim Besser +14 more
core +2 more sources
Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]
Phys. Biol. 13 (2016) 066003, 2016 Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
core +3 more sources
Stress relaxation in F-actin solutions by severing [PDF]
Soft Matter, 2019, 15, 6300-6307, 2019 Networks of filamentous actin (F-actin) are important for the mechanics of most animal cells. These cytoskeletal networks are highly dynamic, with a variety of actin-associated proteins that control cross-linking, polymerization and force generation in ...
Arzash, S. +4 more
core +2 more sources
Regulation of actin cytoskeleton via photolithographic micropatterning
Journal of Innovative Optical Health Sciences, 2023 Actin cytoskeleton plays crucial roles in various cellular functions. Extracellular matrix (ECM) can modulate cell morphology by remodeling the internal cytoskeleton.
Fulin Xing +9 more
doaj +1 more source
NPFs-mediated actin cytoskeleton: a new viewpoint on autophagy regulation. [PDF]
Cell Commun SignalMacroautophagy/autophagy is a lysosome-dependent catabolic process induced by various cellular stress conditions, maintaining the homeostasis of cells, tissues and organs.
Dong Y, Quan C.
europepmc +2 more sources
Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton. [PDF]
Nat Commun, 2023 The filamentous actin (F-actin) cytoskeleton is a composite material consisting of cortical actin and bundled F-actin stress fibers, which together mediate the mechanical behaviors of the cell, from cell division to cell migration. However, as mechanical
Amiri S +6 more
europepmc +2 more sources
Influence of ROCK Pathway Manipulation on the Actin Cytoskeleton Height
Cells, 2022 The actin cytoskeleton with its dynamic properties serves as the driving force for the movement and division of cells and gives the cell shape and structure. Disorders in the actin cytoskeleton occur in many diseases.
Carolin Grandy +3 more
doaj +1 more source
Actin Cytoskeleton Role in the Maintenance of Neuronal Morphology and Long-Term Memory
Cells, 2021 Evidence indicates that long-term memory formation creates long-lasting changes in neuronal morphology within a specific neuronal network that forms the memory trace.
Raphael Lamprecht
doaj +1 more source
Getting cells into shape by calcium-dependent actin cross-linking proteins
Frontiers in Cell and Developmental Biology, 2023 The actin cytoskeleton represents a highly dynamic filament system providing cell structure and mechanical forces to drive a variety of cellular processes.
Franziska Lehne, Sven Bogdan
doaj +1 more source
IEEE Access, 2022 Actin cytoskeleton morphology is able to affect and reflect the cellular mechanical properties. However, due to the lack of efficient approaches to quantifying actin cytoskeleton and mechanical properties, the study of mechanotransduction dynamics is ...
Yi Liu +3 more
doaj +1 more source