Results 31 to 40 of about 297,755 (331)

Alteration of the cortical actin cytoskeleton deregulates Ca2+ signaling, monospermic fertilization, and sperm entry. [PDF]

PLoS ONE, 2008
BackgroundWhen preparing for fertilization, oocytes undergo meiotic maturation during which structural changes occur in the endoplasmic reticulum (ER) that lead to a more efficient calcium response. During meiotic maturation and subsequent fertilization,
A Puppo, Jong T Chun, Giovanni Gragnaniello, Ezio Garante, Luigia Santella   +4 more
doaj   +1 more source

Novel Actin Cytoskeleton. Actin Tubules.

Cell Structure and Function, 2000
In spores of Dictyostelium discoideum three actin filaments are bundled to form a novel tubular structure and the tubules are then organized into rods. These tubular structures we will term actin tubules. Actin tubules are reconstructed from the supernatant of spore homogenates, while the usual actin filaments were bundled after incubation of ...
Masako Osumi, Masazumi Sameshima, David A. Cotter, Dana Mahadeo, Yoshiro Kishi   +4 more
openaire   +4 more sources

Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells [PDF]

, 2018
Imaging the actin cytoskeleton in cells uses a wide range of approaches. Typically, a fluorescent derivative of the small cyclic peptide phalloidin is used to image F-actin in fixed cells. Lifeact and F-tractin are popular for imaging the cytoskeleton in
A Nagasaki, AH Criddle, AJ Spracklen, AM Lengsfeld, B Visegrady, BJ Belin, C Ballestrem, C Ballestrem, C Tiede, C Xie, CW Lee, D Szczesna, E Behrmann, E Wulf, G Lukinavicius, H Aizawa, IN Rybakova, J Ecken von der, J Riedl, J Small, J Wehland, J Wehland, JI Robinson, K Sliogeryte, LD Belmont, M Fritzsche, M Melak, M Nemethova, MA Brehm, MA Michel, MJ Schell, NJ Haywood, SF Wulf, SM Heissler, T Oda, TD Pollard, YL Wang   +36 more
core   +2 more sources

Phosphatidylinositol (4,5)-bisphosphate turnover by INP51 regulates the cell wall integrity pathway in "Saccharomyces cerevisiae" [PDF]

, 2004
Signal transduction pathways are important for the cell to transduce external or internal stimuli where second messengers play an important role as mediators of the stimuli. One important group of second messengers are the phosphoinositide family present
Morales-Johansson, Helena
core   +2 more sources

RACK1 promotes Shigella flexneri actin-mediated invasion, motility, and cell-to-cell spreading

iScience, 2023
Summary: Shigella flexneri is an intracellular bacterium that hijacks the host actin cytoskeleton to invade and disseminate within the colonic epithelium.
Karla N. Valenzuela-Valderas, Elmira Farrashzadeh, Yuen-Yan Chang, Yunnuo Shi, Renee Raudonis, Brendan M. Leung, John R. Rohde, Jost Enninga, Zhenyu Cheng   +8 more
doaj  

PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins

Biology Open, 2016
Super-resolution microscopy (SRM) allows precise localization of proteins in cellular organelles and structures, including the actin cytoskeleton. Yet sample preparation protocols for SRM are rather anecdotal and still being optimized.
Daniela Leyton-Puig, Katarzyna M. Kedziora, Tadamoto Isogai, Bram van den Broek, Kees Jalink, Metello Innocenti   +5 more
doaj   +1 more source

Actin cytoskeleton: Thinking globally, actin’ locally [PDF]

Current Biology, 2000
A class of proteins dubbed pipmodulins bind to and sequester the phospholipid PIP2 in the plasma membrane. Local release of PIP2 controls actin dynamics in specific subcellular regions and plays a critical role in regulating actin-based cell motility and morphogenesis.
Lanier, Lorene M., Gertler, Frank
openaire   +4 more sources

Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton [PDF]

, 2013
Planar cell polarity (PCP) regulates cell alignment required for collective cell movement during embryonic development. This requires PCP/PCP effector proteins, some of which also play essential roles in ciliogenesis, highlighting the long-standing ...
Adam V. Kwiatkowski, AJ Ross, B Schermer, Bishwanath Chatterjee, C Cui, C Jones, C Jones, C Stuckenholz, CB Kimmel, CD Nobes, Cecilia W. Lo, Chandrakala Puligilla, Cheng Cui, CJ Haycraft, CU Stirnimann, CW Sipe, D Huangfu, D Huangfu, D Yelon, Deanne Francis, E Joo, EK Vladar, Elias T. Spiliotis, F Hildebrandt, GJ Pazour, Gregory J. Pazour, Hisato Yagi, HM Phillips, HM Phillips, I Drummond, J Magdalena, J Wang, J Wang, JB Wallingford, JB Wallingford, JL Badano, Jovenal T. San Agustin, K Schmidt, K Takemaru, KC Corbit, KC Corbit, Lisa M. Swanhart, M Castori, M Fliegauf, M Kelly, M Kinoshita, M Montcouquiol, M Simons, Matthew P. Scott, Matthew W. Kelley, Neil A. Hukriede, Q Hu, Q Yu, Qing Yu, R Rohatgi, RA Meseroll, Richard J. Francis, RJ Francis, Rocky Tuan, S Collier, S Maretto, S Saburi, SD Weatherbee, SK Kim, Subramaniam Sanker, T Caspary, T Kudoh, Tania Chatterjee, Terry Tansey, Thomas P. Lozito, TJ Park, X Wen, Xiaoqin Liu, Y Wang, Zhen Zhang   +74 more
core   +4 more sources

The Actin Cytoskeleton and Actin-Based Motility [PDF]

Cold Spring Harbor Perspectives in Biology, 2018
The actin cytoskeleton-a collection of actin filaments with their accessory and regulatory proteins-is the primary force-generating machinery in the cell. It can produce pushing (protrusive) forces through coordinated polymerization of multiple actin filaments or pulling (contractile) forces through sliding actin filaments along bipolar filaments of ...
openaire   +3 more sources

An actin‐based cytoskeleton in archaea [PDF]

Molecular Microbiology, 2011
SummaryIn eukaryotic and bacterial cells, spatial organization is dependent upon cytoskeletal filaments. Actin is a main eukaryotic cytoskeletal element, involved in key processes such as cell shape determination, mechanical force generation and cytokinesis.
Ann-Christin Lindås, Rolf Bernander, Thijs J. G. Ettema   +2 more
openaire   +3 more sources