Results 41 to 50 of about 297,755 (331)

Compartmentalisation and localisation of the translation initiation factor (eIF) 4F complex in normally growing fibroblasts [PDF]

open access: yes, 2006
Previous observations of association of mRNAs and ribosomes with subcellular structures highlight the importance of localised translation. However, little is known regarding associations between eukaryotic translation initiation factors and cellular ...
Barbarese   +82 more
core   +1 more source

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling

open access: yesFrontiers in Immunology, 2021
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term.
Hannah Wurzer   +16 more
doaj   +1 more source

The actin cytoskeleton in ageing and apoptosis [PDF]

open access: yesFEMS Yeast Research, 2005
Regulated cell death, or apoptosis, has evolved to fulfil a myriad of functions amongst multicellular organisms. It is now apparent that programmed cell death occurs in unicellular organisms such as yeast. In yeast, as in higher eukaryotes, the actin cytoskeleton is an essential component of a number of cellular activities, and many of the regulatory ...
Campbell W. Gourlay, Kathryn R. Ayscough
openaire   +3 more sources

Actin Cytoskeleton and Golgi Involvement in Barley stripe mosaic virus Movement and Cell Wall Localization of Triple Gene Block Proteins. [PDF]

open access: yes, 2013
Barley stripe mosaic virus (BSMV) induces massive actin filament thickening at the infection front of infected Nicotiana benthamiana leaves. To determine the mechanisms leading to actin remodeling, fluorescent protein fusions of the BSMV triple gene ...
Bae, Hanhong   +10 more
core   +2 more sources

When fat is not bad: the regulation of actin dynamics by phospholipid signaling molecules

open access: yesFrontiers in Plant Science, 2014
The actin cytoskeleton plays a key role in the plant morphogenesis and is involved in polar cell growth, movement of subcellular organelles, cell division, and plant defense.
Roman ePleskot   +3 more
doaj   +1 more source

Actin-dependent mechanisms in AMPA receptor trafficking. [PDF]

open access: yes, 2014
The precise regulation of AMPA receptor (AMPAR) number and subtype at the synapse is crucial for the regulation of excitatory neurotransmission, synaptic plasticity and the consequent formation of appropriate neural circuits during learning and memory ...
Hanley, Jonathan
core   +2 more sources

Interactions of mitochondria with the actin cytoskeleton

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006
Interactions between mitochondria and the cytoskeleton are essential for normal mitochondrial morphology, motility and distribution. While microtubules and their motors have been established as important factors for mitochondrial transport, emerging evidence indicates that mitochondria interact with the actin cytoskeleton in many cell types. In certain
Istvan R. Boldogh, Liza A. Pon
openaire   +3 more sources

Wnt signalling and the actin cytoskeleton [PDF]

open access: yesOncogene, 2006
The tumour suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumours. APC binds to beta-catenin, a key component of the Wnt signalling pathway, and induces its degradation. In addition to this role, there is increasing evidence for additional roles of APC, including the organization of cytoskeletal networks. APC
Yoshihiro Kawasaki, Tetsu Akiyama
openaire   +2 more sources

Role of actin cytoskeleton in the organization and function of ionotropic glutamate receptors

open access: yesCurrent Research in Structural Biology, 2021
Neural networks with precise connection are compulsory for learning and memory. Various cellular events occur during the genesis of dendritic spines to their maturation, synapse formation, stabilization of the synapse, and proper signal transmission. The
Priyanka Dutta   +3 more
doaj  

Coupling biochemistry and mechanics in cell adhesion: a model for inhomogeneous stress fiber contraction

open access: yes, 2007
Biochemistry and mechanics are closely coupled in cell adhesion. At sites of cell-matrix adhesion, mechanical force triggers signaling through the Rho-pathway, which leads to structural reinforcement and increased contractility in the actin cytoskeleton.
Achim Besser   +14 more
core   +1 more source

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