Results 51 to 60 of about 17,248,721 (282)

Impact of activating transcription factor 4 signaling on lipogenesis in HepG2 cells

open access: yesMolecular Medicine Reports, 2016
Non-alcoholic fatty liver disease (NAFLD) is a rapidly growing health threat that has previously been associated with lipogenesis. The direct effect of endoplasmic reticulum stress (ERS) inhibition on the induction of lipogenesis has not been investigated in hepatocytes in vitro.
Lu-Ping, Ren   +7 more
openaire   +3 more sources

ATF1 (activating transcription factor 1) [PDF]

open access: yes, 1999
Review on ATF1 (activating transcription factor 1), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL
core   +1 more source

ATF2 (activating transcription factor 2) [PDF]

open access: yes, 2008
Review on ATF2 (activating transcription factor 2), with data on DNA, on the protein encoded, and where the gene is ...
Sevilla, A, Lazo, PA
core   +1 more source

Granulocyte-activating mediators (GRAM) [PDF]

open access: yes, 1987
In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A.   +8 more
core   +1 more source

Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone.

open access: yesPLoS ONE, 2009
Parathyroid hormone (PTH) is a potent anabolic agent for the treatment of osteoporosis. However, its mechanism of action in osteoblast and bone is not well understood.
Shibing Yu   +12 more
doaj   +1 more source

Activating transcription factor 4 increases chemotherapeutics resistance of human hepatocellular carcinoma [PDF]

open access: yesCancer Biology & Therapy, 2012
It has been reported that activating transcription factor 4 (ATF4) increases the processes of tumor growth, metastasis and drug resistance. However, the role played by ATF4 in chemoresistance of hepatocellular carcinoma (HCC) remains unknown. Clarification of this role of ATF4 in HCC could greatly benefit the efficacy of clinical treatment of HCC.
Zhuhong, Zhang   +13 more
openaire   +2 more sources

ATF5 (activating transcription factor 5) [PDF]

open access: yes, 2011
Review on ATF5 (activating transcription factor 5), with data on DNA, on the protein encoded, and where the gene is ...
N Wong, AKK Ching, Wong, N, Ching, AKK
core   +1 more source

The function of the protein phosphatase Glc7p in transcription termination, RNA processing and transcriptional regulation of ribosomal protein genes [PDF]

open access: yes, 2007
Gene transcription in general can be subdivided into three main phases: transcription initiation, elongation and termination. The enzyme that accomplishes transcription of protein coding genes, snRNAs and snoRNAs is RNA polymerase II (RNAP II).
Röck, Salome
core   +1 more source

Platelet transcriptome profiles provide potential therapeutic targets for elderly acute myelocytic leukemia patients

open access: yesJournal of Translational Medicine, 2021
Highlights 1. Gene transcript profiles in the elderly AML patients are different from those in young patients. 2. Statistical analysis reveals the down-regulation of protein processing in ER and pathways related to immunity in elderly patients. 3.
Jizhang Bao   +15 more
doaj   +1 more source

Bayesian model-based inference of transcription factor activity [PDF]

open access: yes, 2007
<b>Background:</b> In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is considered to be an accurate surrogate for the true ...
Rogers, S   +5 more
core   +1 more source

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