Results 11 to 20 of about 1,622,433 (301)
Microphysiological Modeling of the Structure and Function of Neuromuscular Transmitter Release Sites
Frontiers in Synaptic Neuroscience, 2022 The general mechanism of calcium-triggered chemical transmitter release from neuronal synapses has been intensely studied, is well-known, and highly conserved between species and synapses across the nervous system.
Rozita Laghaei, Stephen D. Meriney
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Mechanisms controlling the trafficking, localization, and abundance of presynaptic Ca2+ channels
Frontiers in Molecular Neuroscience, 2023 Voltage-gated Ca2+ channels (VGCCs) mediate Ca2+ influx to trigger neurotransmitter release at specialized presynaptic sites termed active zones (AZs). The abundance of VGCCs at AZs regulates neurotransmitter release probability (Pr), a key presynaptic ...
Karen L. Cunningham, J. Troy Littleton
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Zone-based Layer Activation [PDF]
Proceedings of the 12th ACM International Workshop on Context-Oriented Programming and Advanced Modularity, 2020 Scoping behavior adaptations using dynamic extent is a crucial part of Context-oriented Programming (COP). In a synchronous execution model, dynamic extent ensures the activation of a layer for the entire duration of a block. An asynchronous execution model, however, breaks the intended semantics of dynamic extent.
Stefan Ramson +3 more
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The Decade of Super-Resolution Microscopy of the Presynapse
Frontiers in Synaptic Neuroscience, 2020 The presynaptic compartment of the chemical synapse is a small, yet extremely complex structure. Considering its size, most methods of optical microscopy are not able to resolve its nanoarchitecture and dynamics.
Georgii Nosov +3 more
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Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses
Biomolecules, 2022 Synaptic transmission is essential for controlling motor functions and maintaining brain functions such as walking, breathing, cognition, learning, and memory.
Kenji Takikawa, Hiroshi Nishimune
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Protein phase separation hotspots at the presynapse
Open Biology, 2022 Fundamental discoveries have shaped our molecular understanding of presynaptic processes, such as neurotransmitter release, active zone organization and mechanisms of synaptic vesicle (SV) recycling.
Janin Lautenschläger
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Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR
eLife, 2021 It has long been proposed that leukocyte common antigen-related receptor protein tyrosine phosphatases (LAR-RPTPs) are cell-adhesion proteins that control synapse assembly.
Javier Emperador-Melero +2 more
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Spotlight on the active zone [PDF]
Cellular Logistics, 2011 A chemical synapse is a junction between a pre-synaptic neuron and a post-synaptic cell, neuron or non-neuron, through which signals are transmitted by neurotransmitters.The active zone is the site...
Nava, Segev, Simon, Alford
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Sea Beam Survey of an Active Strike-Slip Fault: The San Clemente Fault in the California Continental Borderland [PDF]
, 1989 The San Clemente fault, located in the California Continental Borderland, is an active, northwest trending, right-lateral, wrench fault. Sea Beam data are used to map the major tectonic landforms associated with active submarine faulting in detail ...
de Moustier, Christian +4 more
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Frontiers in Molecular Neuroscience, 2022 Both paralogs of the calcium-dependent activator protein for secretion (CAPS) are required for exocytosis of synaptic vesicles (SVs) and large dense core vesicles (LDCVs).
Angelina Staudt +13 more
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