Results 21 to 30 of about 1,622,433 (301)

Cellular and Molecular Anatomy of the Human Neuromuscular Junction

open access: yesCell Reports, 2017
The neuromuscular junction (NMJ) plays a fundamental role in transferring information from lower motor neuron to skeletal muscle to generate movement.
Ross A. Jones   +13 more
doaj   +1 more source

Ultrafast endocytosis at Caenorhabditis elegans neuromuscular junctions

open access: yeseLife, 2013
Synaptic vesicles can be released at extremely high rates, which places an extraordinary demand on the recycling machinery. Previous ultrastructural studies of vesicle recycling were conducted in dissected preparations using an intense stimulation to ...
Shigeki Watanabe   +6 more
doaj   +1 more source

Distinct Target-Specific Mechanisms Homeostatically Stabilize Transmission at Pre- and Post-synaptic Compartments

open access: yesFrontiers in Cellular Neuroscience, 2020
Neurons must establish and stabilize connections made with diverse targets, each with distinct demands and functional characteristics. At Drosophila neuromuscular junctions (NMJs), synaptic strength remains stable in a manipulation that simultaneously ...
Pragya Goel   +5 more
doaj   +1 more source

The Presynaptic Active Zone [PDF]

open access: yesNeuron, 2012
Neurotransmitters are released by synaptic vesicle exocytosis at the active zone of a presynaptic nerve terminal. In this review, I discuss the molecular composition and function of the active zone. Active zones are composed of an evolutionarily conserved protein complex containing as core constituents RIM, Munc13, RIM-BP, α-liprin, and ELKS proteins ...
openaire   +2 more sources

Myosin V functions as a vesicle tether at the plasma membrane to control neurotransmitter release in central synapses

open access: yeseLife, 2018
Synaptic vesicle fusion occurs at specialized release sites at the active zone. How refilling of release sites with new vesicles is regulated in central synapses remains poorly understood. Using nanoscale-resolution detection of individual release events
Dario Maschi   +2 more
doaj   +1 more source

Seismicity relocation and fault structure near the Leech River Fault Zone, southern Vancouver Island [PDF]

open access: yes, 2018
Relatively low rates of seismicity and fault loading have made it challenging to correlate microseismicity to mapped surface faults on the forearc of southern Vancouver Island.
Li, Ge   +3 more
core   +1 more source

Active zone self-similarity of fractal sierpinski antenna verified using infra-red thermograms [PDF]

open access: yes, 1999
The surface current distribution of a Sierpinski fractal antenna shows a self-similar behaviour determined by the self-similar properties of its geometry.
Aguasca Solé, Alberto   +4 more
core   +2 more sources

Regulation of presynaptic Ca2+ channel abundance at active zones through a balance of delivery and turnover

open access: yeseLife, 2022
Voltage-gated Ca2+ channels (VGCCs) mediate Ca2+ influx to trigger neurotransmitter release at specialized presynaptic sites termed active zones (AZs). The abundance of VGCCs at AZs regulates neurotransmitter release probability (Pr), a key presynaptic ...
Karen L Cunningham   +3 more
doaj   +1 more source

A multiscale constitutive model for intergranular stress corrosion cracking in type 304 austenitic stainless steel [PDF]

open access: yes, 2013
Intergranular stress corrosion cracking (IGSCC) is a fracture mechanism in sensitised austenitic stainless steels exposed to critical environments where the intergranular cracks extends along the network of connected susceptible grain boundaries.
Rahimi, S, Siddiq, A
core   +2 more sources

An Integrated Framework for Sensing Radio Frequency Spectrum Attacks on Medical Delivery Drones

open access: yes, 2020
Drone susceptibility to jamming or spoofing attacks of GPS, RF, Wi-Fi, and operator signals presents a danger to future medical delivery systems. A detection framework capable of sensing attacks on drones could provide the capability for active responses.
Kulp, Philip H., Mei, Nagi
core   +1 more source

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