This review highlights the characteristic odor markers of illicit drugs, emphasizing volatile markers from both natural and synthetic sources, and explores the shift from canine‐based detection to emerging noncontact sensing technologies. Illicit drug use remains a global concern, requiring effective detection methods to counter evolving concealment ...
Minwoo Kim +4 more
wiley +1 more source
Benzochromanone and Benzochromene Natural Products: Synthetic Strategies and Total Syntheses
This work outlines synthetic strategies for natural products with benzochromanone and benzochromene cores. Key achievements include total syntheses of xanthones, blennolide C, gonytolide C, and teretifolione B. Spirochromanone intermediates, benzyne–furan Diels–Alder reactions, and enzymatic resolution enabled efficient and enantioselective access to ...
Takuya Kumamoto
wiley +1 more source
Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj +12 more
wiley +1 more source
Enantioselective Metallophosphite-Catalyzed C-Acylation of Nitrones
Mary Robert Garrett +2 more
openalex +2 more sources
The Effects of Cerulenin, an Inhibitor of Protein Acylation, on the Two Phases of Glucose-Stimulated Insulin Secretion [PDF]
Susanne G. Straub +4 more
openalex +1 more source
meta-Selective Radical Acylation of Electron-rich Arenes [PDF]
Yamato Goto +3 more
openalex +1 more source
Artificial lipidation of proteins and peptides: from mechanism to clinical applications
Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley +1 more source
Attenuating ABHD17 isoforms augments the S -acylation and function of NOD2 and a subset of Crohn’s disease-associated NOD2 variants [PDF]
Charneal L. Dixon +4 more
openalex +1 more source
A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge +3 more
wiley +1 more source

