Results 131 to 140 of about 126,317 (283)
Smart Molecules, EarlyView.This review elucidates the photophysical mechanisms of cellulose‐based room temperature phosphorescent materials and systematically outlines their construction strategies, such as cluster emission center engineering. This article demonstrates their applications in fields like information encryption and bioimaging, and looks ahead to the core challenges
Shasha Wu +10 more
wiley +1 more source
The Chemical Record, EarlyView.This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Peptide binding at the gasdermin D exosite reveals the structural basis for targeting the site
Acta Crystallographica Section D, EarlyView.We describe the first structure of gasdermin D with a putative caspase inhibitor peptide analog at 1.6 Å resolution. This work suggests potential druggability of gasdermin D at the exosite by leveraging structure‐based computational design with biochemical characterization.Gasdermin D (GSDMD) has been identified as a critical component of the ...
Renjing Wang +15 more
wiley +1 more source
Molecular Structure of Endotoxins from Gram-negative Marine Bacteria: An Update (review) [PDF]
, 2007 A. Molinaro +5 more
core +1 more source
Cefdinir binding to a class A β‐lactamase revealed by serial cryo‐crystallography
Acta Crystallographica Section D, EarlyView.Serial cryo‐crystallography reveals the structure of the extended‐spectrum β‐lactamase CTX‐M‐14 in complex with the third‐generation cephalosporin antibiotic cefdinir.One of the most common resistance mechanisms against antibiotics employed by Gram‐negative bacteria involves the production of β‐lactamases, resulting in rapid hydrolysis of the ...
Gargi Gore +4 more
wiley +1 more source
Amylin analogues as a novel perspective in anti‐obesity therapy
British Journal of Pharmacology, EarlyView.Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT In the year 2000 the first once daily long‐acting bioengineered insulin analogue (LAIA), insulin glargine (‘glargine’), a true basal insulin (BI), became available for clinical use. This led to the decline in the 50‐year‐old era and prominence of the intermediate‐acting insulins, neutral protamine Hagedorn (NPH) and lente, requiring twice ...
Geremia B. Bolli +9 more
wiley +1 more source
Catalytic asymmetric acylation reactions using isothiourea catalysts: a Decade's update. [PDF]
RSC AdvKhatua SA, Ghosh R, Simlandy AK.
europepmc +1 more source
A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer
The FEBS Journal, EarlyView.Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge +3 more
wiley +1 more source
S-acylation and membrane localization of the small GTPase ARL15 are mediated by the Golgi S-acyltransferases ZDHHC7 and ZDHHC3. [PDF]
J Biol ChemChino T +7 more
europepmc +1 more source