Results 151 to 160 of about 126,317 (283)
Lewis acid/NHC dual catalysis for regioselective vicinal decarboxylative carbonylation-acylation of alkenes. [PDF]
Chem SciYang ML, Wu XF.
europepmc +1 more source
In vitro reconstitution in membrane environment reveals critical lipid dependence of substrate S-acylation by protein palmitoyltransferase enzymes. [PDF]
J Biol ChemMondal T, Banerjee A.
europepmc +1 more source
Tuning adsorption and morphology in poly(glutamic acid) via controlled acidic partial deprotection
Polymer International, Volume 75, Issue 6, Page 490-497, June 2026.Partial deprotection of poly(glutamic acid) generates morphologies and assemblies that match fully deprotected polypeptides in small‐molecule adsorption, extending to block copolypeptides with pH‐dependent effects. Abstract Synthetic polypeptides prepared from N‐carboxyanhydride (NCA) monomers are important platforms for environmental and medical ...
Hunter Wood +5 more
wiley +1 more source
Role of the transmembrane domain in severe acute respiratory syndrome (SARS) coronavirus 2 spike for palmitoylation and membrane fusion. [PDF]
Protein SciAbdulrahman DA, Veit M.
europepmc +1 more source
Functional dynamics of water in New Delhi metallo‐β‐lactamase catalysis
Protein Science, Volume 35, Issue 6, June 2026.Abstract Water plays a critical role in the hydrolysis of antibiotics by New Delhi metallo‐β‐lactamases (NDMs). The reaction proceeds through a nucleophilic attack on the β‐lactam ring, followed by cleavage of the C–N bond and formation of an anionic nitrogen intermediate. This intermediate is then protonated by a water molecule diffusing from the bulk
Palanisamy Kandhan +3 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4706-4717, June 2026.ABSTRACT Aim To characterise the metabolic benefits of a GLP‐1/apelin hybrid peptide, namely exendin‐4‐linker‐apelin (ELA), and associated acylated forms, including ELA‐Lys12(γGluPal), ELA‐Lys27(γGluPal) and ELA‐Lys38(γGluPal). Methods Concentration‐ and receptor‐dependent effects of the peptides on insulin secretion and beta‐cell turnover were ...
Ananyaa Sridhar +5 more
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Intermolecular Electrophilic Germylation Using GeCl4 and Al2Cl6
Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.While electrophilic aromatic substitution is well‐established for carbon and silicon‐based electrophiles, it is extremely underdeveloped for germanium. Herein we report the first effective intermolecular Germa–Friedel–Crafts reaction. The process can be modified to enable selective synthesis of the mono‐ or the di‐aryl germane derivatives, ArGeCl3 and ...
Justyna Łosiewicz +4 more
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Plant Biotechnology Journal, Volume 24, Issue 6, Page 3691-3707, June 2026.ABSTRACT Grapevine powdery mildew, caused by the fungal pathogen Erysiphe necator, severely impacts plant growth and berry quality. However, the grapevine receptors and molecular mechanisms underlying grapevine resistance to E. necator remain poorly understood.
Yajuan Li +9 more
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Plant Biotechnology Journal, Volume 24, Issue 6, Page 4139-4158, June 2026.BAHD acyltransferases drive metabolic diversification in plants by coupling conserved catalytic scaffolds with regulatory flexibility, enabling stress adaptation and ecological specialisation. ABSTRACT BAHD acyltransferases constitute one of the most versatile enzyme superfamilies in plants, catalysing the acylation of alcohols, amines, polyamines, and
Muhammad Mubashar Zafar +7 more
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Plant Biotechnology Journal, Volume 24, Issue 6, Page 3803-3820, June 2026.ABSTRACT Plant‐derived secondary metabolites act as regulators of in planta defence. Plant phenylpropanoid metabolic compounds, including final metabolites such as lignin and flavonoids, and a few intermediate metabolites play critical roles in defence.
Dan Chen +9 more
wiley +1 more source