Results 141 to 150 of about 103,057 (335)
Animal Research and One Health, EarlyView.The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem +5 more
wiley +1 more source
Acylation and alkylation of 1,3-dimethoxybenzene in polyphosphoric acid [PDF]
, 1969 T. R. KASTURI, K. M. DAMODARAN
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Lactylation in cancer biology: Unlocking new avenues for research and therapy
Cancer Communications, EarlyView.Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou +6 more
wiley +1 more source
Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application
Chemistry &Biodiversity, EarlyView.ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade +4 more
wiley +1 more source
Functional Analysis of Histidine‐Dependent Self‐Cleaving RNAs Obtained by In Vitro Selection
ChemBioChem, EarlyView.Ribozymes can be nucleic acid medicines given their catalytic activity. We attempted to obtain functional RNAs that mimic ribonuclease A catalytic mechanisms. Functional RNAs with high histidine specificity were obtained, suggesting that histidine acts in active structure formation.
Nae Sakimoto +8 more
wiley +1 more source
Synthesis of pyrrolo[1,2-a]indole-1,8(5H)-diones as new synthons for developing novel tricyclic compounds of pharmaceutical interest [PDF]
, 2004 In the course of our work aimed at developing novel heterocycles of pharmaceutical interest, a new tricycle, the tetrahydropyrrolo[1,2-a]indole-1,8-dione, has been synthesized by an intramolecular Friedel-Crafts acylation, as a synthon suitable to be ...
Mura, Alessio +4 more
core
ChemBioChem, EarlyView.At the intersection of chemical biology, plant imaging, and contemporary art, this review introduces the concept of chembioart. By tracing how chemical reporters illuminate plant biomolecules in vivo, their role not only in advancing scientific understanding but also in inspiring transdisciplinary collaborations and visual expression is highlighted ...
Marie Hinnebo +4 more
wiley +1 more source
4, 5-Substituted Pyridazines. VII. Synthesis and Acylation of 3, 4-Dichloro-5-aminopyridazine.
, 1958 Tsukasa Kuraishi
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KOSTANECKI-ROBINSON ACYLATION OF 8-PROPIONYL-AND 8-BUTYRYLπ- UMBELLIFERONES [PDF]
, 1960 D. N. SHAH, S. J. CONTRACTOR
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