Results 41 to 50 of about 103,353 (290)
Human NK Cells and Herpesviruses: Mechanisms of Recognition, Response and Adaptation [PDF]
Frontiers in Microbiology, 2019 NK cells contribute to early defenses against viruses through their inborn abilities that include sensing of PAMPs and inflammatory signals such as cytokines or chemokines, recognition, and killing of infected cells through activating surface receptors engagement. Moreover, they support adaptive responses via Ab-dependent mechanisms, triggered by CD16,
Mariella Della Chiesa +9 more
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Activation of human natural killer cells by Plasmodium falciparum [PDF]
, 2003 The purpose of work described in this thesis was to (i) determine the contribution of innate immune responses to the early pro-inflammatory cytokine response to Plasmodium falciparum, (ii) describe the kinetics and ...
Artavanis-Tsakonas, Katerina
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Journal of Clinical and Translational Science, 2023 OBJECTIVES/GOALS: The primary objective of this study was to define the transcriptomes and transcriptional regulatory network required for the development and function of adaptive Natural Killer (NK) cells in donors with latent human cytomegalovirus ...
Mohamed Khalil +2 more
doaj +1 more source
Influenza vaccination in immunosuppressed and healthy individuals : DC-induced regulatory NK cell-function [PDF]
, 2011 Infection with the human immunodeficiency virus (HIV) leads to immunosuppression, mainly through depletion of CD4+ T cells. Anti-retroviral therapy (ART) inhibits virus replication and thereby promotes recovery of T cell numbers and reconstitution of ...
Fritz, Stefanie
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NK and T Cell Immunological Signatures in Hospitalized Patients with COVID-19
Cells, 2021 Severe acute respiratory syndrome caused by coronavirus 2 emerged in Wuhan (China) in December 2019 and has severely challenged the human population. NK and T cells are involved in the progression of COVID-19 infection through the ability of NK cells to ...
Laura Bergantini +7 more
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Natural Killer Cells in Multiple Sclerosis: Entering the Stage
Frontiers in Immunology, 2022 Studies investigating the immunopathology of multiple sclerosis (MS) have largely focused on adaptive T and B lymphocytes. However, in recent years there has been an increased interest in the contribution of innate immune cells, amongst which the natural
Jarne Beliën, An Goris, Patrick Matthys
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Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection
Frontiers in Immunology, 2018 Human cytomegalovirus (HCMV) co-infection is highly prevalent within HIV-1 cohorts and is an important cofactor in driving ongoing immune activation, even during effective antiretroviral treatment.
Dimitra Peppa +7 more
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IL-2–dependent adaptive control of NK cell homeostasis [PDF]
Journal of Experimental Medicine, 2013 Activation and expansion of T and B lymphocytes and myeloid cells are controlled by Foxp3+ regulatory T cells (T reg cells), and their deficiency results in a fatal lympho- and myeloproliferative syndrome. A role for T reg cells in the homeostasis of innate lymphocyte lineages remained unknown.
Gasteiger, Georg +4 more
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Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells [PDF]
, 2011 The outcome of viral infections is dependent on the function of CD8+ T cells which are tightly regulated by costimulatory molecules. The NK cell receptor 2B4 (CD244) is a transmembrane protein belonging to the Ig superfamily which can also be expressed ...
Lunemann, Sebastian +35 more
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Frontiers in ImmunologyDevelopment of antigen-specific memory upon pathogen exposure is a hallmark of the adaptive immune system. While natural killer (NK) cells are considered part of the innate immune system, humans exposed to the chronic viral pathogen cytomegalovirus (CMV)
M. Kazim Panjwani +8 more
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