Bovine NK cells can produce gamma interferon in response to the secreted mycobacterial proteins ESAT-6 and MPP14 but not in response to MPB70 [PDF]
, 2005 Bovine NK cells have recently been characterized and the present study describes the interaction between NK cells, antigen-presenting cells, and secreted mycobacteriall proteins.
Jungersen, Gregers +15 more
core +1 more source
Novel Mouse Model of Murine Cytomegalovirus–Induced Adaptive NK Cells [PDF]
ImmunoHorizons, 2022 Abstract NK cells are important mediators of viral control with the capacity to form adaptive immune features following infection. However, studies of infection-induced adaptive NK cells require adoptive cell transfer to lower the precursor frequency of “Ag-specific” NK cells, potentially limiting the diversity of the NK cell response ...
Isaac J Jensen +3 more
openaire +3 more sources
Influenza vaccination in immunosuppressed and healthy individuals : DC-induced regulatory NK cell-function [PDF]
, 2011 Infection with the human immunodeficiency virus (HIV) leads to immunosuppression, mainly through depletion of CD4+ T cells. Anti-retroviral therapy (ART) inhibits virus replication and thereby promotes recovery of T cell numbers and reconstitution of ...
Fritz, Stefanie
core +1 more source
Human NK Cells and Herpesviruses: Mechanisms of Recognition, Response and Adaptation [PDF]
Frontiers in Microbiology, 2019 NK cells contribute to early defenses against viruses through their inborn abilities that include sensing of PAMPs and inflammatory signals such as cytokines or chemokines, recognition, and killing of infected cells through activating surface receptors engagement. Moreover, they support adaptive responses via Ab-dependent mechanisms, triggered by CD16,
Mariella Della Chiesa +9 more
openaire +3 more sources
Activation of human natural killer cells by Plasmodium falciparum [PDF]
, 2003 The purpose of work described in this thesis was to (i) determine the contribution of innate immune responses to the early pro-inflammatory cytokine response to Plasmodium falciparum, (ii) describe the kinetics and ...
Artavanis-Tsakonas, Katerina
core +1 more source
Proteomic characterization of human CMV-driven adaptive NK cells
, 2022 Human Natural killer (NK) cells are a lymphocyte population of innate immunity, usually short-living and capable of providing rapid responses against viral infections and tumors without prior sensitization.
Di Silvestre Dario +10 more
core +1 more source
Cancer Research, 2016 Human cytomegalovirus (CMV)-induced adaptive natural killer (NK) cells display distinct phenotypic and functional characteristics, including properties of immune memory.
D. Sarhan +8 more
semanticscholar +1 more source
Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]
, 2013 Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Gregson, John NS +5 more
core +1 more source
NK and T Cell Immunological Signatures in Hospitalized Patients with COVID-19
Cells, 2021 Severe acute respiratory syndrome caused by coronavirus 2 emerged in Wuhan (China) in December 2019 and has severely challenged the human population. NK and T cells are involved in the progression of COVID-19 infection through the ability of NK cells to ...
Laura Bergantini +7 more
doaj +1 more source
Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection
Frontiers in Immunology, 2018 Human cytomegalovirus (HCMV) co-infection is highly prevalent within HIV-1 cohorts and is an important cofactor in driving ongoing immune activation, even during effective antiretroviral treatment.
Dimitra Peppa +7 more
doaj +1 more source