Results 61 to 70 of about 2,950 (156)
ADAR2 expression is reduced in CHD patients.
, 2019 (A) ADAR1 p110 is strongly expressed in brain cerebral hemispheres as compared to left heart ventricle. The Y-axis represented the log10 of the transcript per million (TPM) value. The whiskers represent the maximum and minimum values.
Faiza Altaf (6650675) +5 more
core +1 more source
The FASEB Journal, Volume 39, Issue 24, 31 December 2025.A detergent‐based method, combined with immunoprecipitation using an anti‐P‐body component‐specific antibody, was used to isolate RNAs associated with RNA processing bodies (PBs) from both neuronal and glial cells. In neurons, β‐amyloid oligomers helped to trap specific mRNAs related to neuronal differentiation into PBs.
Sritama Ray +2 more
wiley +1 more source
Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.Gastric precancerous lesions undergo dynamic epigenetic alterations—including DNA methylation, 5‐hydroxymethylcytosine, non‐coding RNAs, and RNA editing—throughout the Correa's cascade. The integration of these multi‐omics epigenetic signatures facilitates non‐invasive risk stratification, which guides personalised surveillance strategy and targeted ...
Kewei Ma +4 more
wiley +1 more source
Evaluation of Engineered CRISPR-Cas-Mediated Systems for Site-Specific RNA Editing
Cell Reports, 2020 Summary: Site-directed RNA editing approaches offer great potential to correct genetic mutations in somatic cells while avoiding permanent off-target genomic edits.
Ryan J. Marina +4 more
doaj +1 more source
Advanced Science, Volume 12, Issue 42, November 13, 2025.This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen +7 more
wiley +1 more source
Exercise-Induced ADAR2 Protects against Nonalcoholic Fatty Liver Disease through miR-34a
, 2022 Nonalcoholic fatty liver disease (NAFLD) is a growing health problem that is closely associated with insulin resistance and hereditary susceptibility. Exercise is a beneficial approach to NAFLD. However, the relief mechanism of exercise training is still
Song, Meiyi +11 more
core +1 more source
Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing
Cell Reports, 2020 Summary: Adenosine-to-inosine RNA editing is catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes that deaminate adenosine to inosine. Although many RNA editing sites are known, few trans regulators have been identified.
Emily C. Freund +6 more
doaj +1 more source
Engineered RNA Devices for In Vivo Targeted Therapeutics via Advanced Delivery Systems
Aggregate, Volume 6, Issue 11, November 2025.Schematic illustration of engineered RNA devices for in vivo targeted therapeutics via advanced delivery systems. ABSTRACT Engineered RNA devices can identify disease‐specific markers and precisely regulate gene expression, which is of great significance to the development of precision medicine.
Wei Luo +6 more
wiley +1 more source
Genome Biology, 2017 Background Adenosine-to-inosine (A-to-I) editing of dsRNA by ADAR proteins is a pervasive epitranscriptome feature. Tens of thousands of A-to-I editing events are defined in the mouse, yet the functional impact of most is unknown. Editing causing protein
Jacki E. Heraud-Farlow +10 more
doaj +1 more source
Autoregulation of ADAR2 function by RNA editing.
, 2005 ADAR2 is a double-stranded RNA-specific adenosine deaminase involved in the editing of mammalian RNAs by the site-selective conversion of adenosine to inosine.
Feng, Yi
core