Applied Sciences, 2020 Scrophularia buergeriana (SB) Miq. (Scrophulariaceae) has been used to help cure swelling and fever and has reported antioxidant and neuro-protective effects.
Hae Jin Lee +3 more
doaj +1 more source
Hepatitis C Virus Nonstructural 5A Protein Inhibits Lipopolysaccharide-Mediated Apoptosis of Hepatocytes by Decreasing Expression of Toll-Like Receptor 4 [PDF]
, 2017 Background. Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) has been shown to modulate multiple cellular processes, including apoptosis. The aim of this study was to assess the effects of HCV NS5A on apoptosis induced by Toll-like receptor (TLR ...
Arai, Makoto +12 more
core
Nucleotide specificity of the enzymatic and motile activities of dynein, kinesin, and heavy meromyosin. [PDF]
, 1991 The substrate specificities of dynein, kinesin, and myosin substrate turnover activity and cytoskeletal filament-driven translocation were examined using 15 ATP analogues.
Furusawa, K +6 more
core +2 more sources
Niraparib in ovarian cancer. results to date and clinical potential [PDF]
, 2017 Ovarian cancer is the first cause of death from gynaecological malignancy. Germline mutation in BRCA1 and 2, two genes involved in the mechanisms of reparation of DNA damage, are showed to be related with the incidence of breast and ovarian cancer, both ...
Benedetti Panici, Pierluigi +5 more
core +1 more source
Ferrichrome identified from induces apoptosis through its iron-binding site in gastric cancer cells
Tumor Biology, 2017 Ferrichrome is known to be a siderophore, but it was recently identified as a tumor-suppressive molecule derived from Lactobacillus casei ATCC334 ( L. casei ). In the present study, we investigated the effects of ferrichrome in gastric cancer cells. Cell
Masami Ijiri +9 more
doaj +1 more source
Triple negative breast cancer: new perspectives for targeted therapies [PDF]
, 2015 Breast cancer is a heterogeneous disease, encompassing a large number of entities showing different morphological features and having clinical behaviors.
Caruso, Davide +8 more
core +1 more source
On the kinetic and allosteric regulatory properties of the ADP-glucose pyrophosphorylase from Rhodococcus jostii: An approach to evaluate glycogen metabolism in oleaginous bacteria [PDF]
, 2016 Rhodococcus spp. are oleaginous bacteria that accumulate glycogen during exponential growth. Despite the importance of these microorganisms in biotechnology, little is known about the regulation of carbon and energy storage, mainly the relationship ...
Alvarez, Hector Manuel +4 more
core +1 more source
Poly(Adenosine Diphosphate Ribose) Synthesis during Herpes Simplex Virus Infection
Intervirology, 1979 Immediately after infection of baby hamster kidney cells with herpes simplex virus (HSV), cellular DNA synthesis was blocked, while extensive HSV DNA synthesis began. These dramatic alterations of the control mechanisms for these two DNA synthesizing systems were not accompanied by a change in the poly(adenosine diphosphate ribose) polymerase activity.
W E, Müller +3 more
openaire +2 more sources
, 2005 GDP-mannose pyrophosphorylase gene (ManC) of Escherichia coli (E. coli) O157 was cloned and expressed as a highly soluble protein in E. coli BL21 (DE3). The enzyme was subsequently purified using hydrophobic and ion exchange chromatographies. ManC showed
Hwang, Bum-Yeol +6 more
core
Drug-like antagonists of P2Y receptors — from lead identification to drug development [PDF]
, 2016 P2Y receptors are expressed in virtually all cells and tissue types and mediate an astonishing array of biological functions, including platelet aggregation, smooth muscle cell proliferation, and immune regulation.
Conroy, Sean +3 more
core +1 more source