Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals [PDF]
, 2016 Raw data for Fig. S2.
Alberto Puliafito +9 more
core +16 more sources
Positive Chemotactic Flasklike Colloidal Motors Propelled by Rotary FoF1-ATP Synthases
ResearchLiving microorganisms can perform directed migration for foraging in response to a chemoattractant gradient. We report a biomimetic strategy that rotary FoF1-ATPase (adenosine triphosphatase)-propelled flasklike colloidal motors exhibit positive ...
Yue Li, Yingjie Wu, Qiang He
doaj +1 more source
Progress in targeted therapy for breast cancer
Chronic Diseases and Translational Medicine, 2018 Breast cancer is a multistep, multifactorial, and heterogeneous disease. Significant transformations have occurred in the systemic management of breast cancer in the past decade.
Jie Ju, An-Jie Zhu, Peng Yuan
doaj +1 more source
Coordinated transcriptional regulation between a reactive oxygen species-responsive gene network and the circadian clock in Arabidopsis thaliana : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Plant Biology at Massey University, Plant Biology, New Zealand [PDF]
, 2012 Most organisms have evolved endogenous biological clocks as internal timekeepers to fine-tune physiological processes to the external environment. Energetic cycles such as photosynthesis and glycolytic cycles are physiological processes that have ...
Lai, Alvina Grace
core
Effects of DTX3L on the cell proliferation, adhesion, and drug resistance of multiple myeloma cells
Tumor Biology, 2017 Cell adhesion–mediated drug resistance is an important factor that influences the effects of chemotherapy in multiple myeloma. DTX3L, a ubiquitin ligase, plays a key role in cell-cycle-related process.
Yaodong Shen +3 more
doaj +1 more source
Concentration and synthesis of phosphoribosylpyrophosphate in erythrocytes from normal, hyperuricemic, and gouty subjects. [PDF]
, 1971 Phosphoribosylpyrophosphate (PRPP) synthetase activity and the intracellular concentration of PRPP were assayed in erythrocytes from patients with primary hyperuricemia and primary metabolic gout.
Meyskens, FL, Williams, HE
core
Calcium-RasGRP2-Rap1 signaling mediates CD38-induced migration of chronic lymphocytic leukemia cells
Blood Advances, 2018 : CD38 is a transmembrane exoenzyme that is associated with poor prognosis in chronic lymphocytic leukemia (CLL). High CD38 levels in CLL cells are linked to increased cell migration, but the molecular basis is unknown.
Silvia Mele +4 more
doaj +1 more source
Unlocking Therapeutic Potential of Poly(Adenosine Diphosphate Ribose) Polymerase (PARP) Inhibitors in Metastatic Breast Cancer With BRCA Gene Mutations: A Narrative Review. [PDF]
Cureus, 2023 Jain P.
europepmc +1 more source
Do Not Forget Poly (Adenosine Diphosphate-Ribose) Polymerase Inhibitors in Ovarian Carcinosarcoma. [PDF]
Cureus, 2022 Magalhães D, Bartosch C, Abreu MH.
europepmc +1 more source
Programmed death ligand 1, poly adenosine diphosphate ribose polymerase, and vascular endothelial growth factor receptor inhibition: a potential combination regimen for targeting triple-negative breast cancer? [PDF]
Int J Surg, 2023 Abdul Wahid M +5 more
europepmc +1 more source