Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells [PDF]
, 2013 published_or_final_versio
Chen, YH +7 more
core +1 more source
Journal of Biological Chemistry, 1968 An enzyme associated with mammalian chromatin catalyzed the transfer of the adenosine diphosphate ribose moiety of nicotinamide adenine dinucleotide to histone with the simultaneous release of nicotinamide. A successive transfer of the ADP-ribose moiety resulted in the formation and elongation of a homopolymer with repeating ADP-ribose units ...
Y, Nishizuka +3 more
openaire +2 more sources
First-line treatment of advanced ovarian cancer: an expert update
Libri Oncologici, 2020 Ovarian cancer is the fifth most common cause of death among malignant diseases in women in Europe. The standard treatment is cytoreductive surgery, followed by platinum-taxane based chemotherapy.
Branka Petrić-Miše
doaj +1 more source
Hepatitis C Virus Nonstructural 5A Protein Inhibits Lipopolysaccharide-Mediated Apoptosis of Hepatocytes by Decreasing Expression of Toll-Like Receptor 4 [PDF]
, 2017 Background. Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) has been shown to modulate multiple cellular processes, including apoptosis. The aim of this study was to assess the effects of HCV NS5A on apoptosis induced by Toll-like receptor (TLR ...
Arai, Makoto +12 more
core
Failure to detect "cap" structures in mitochondrial DNA-coded poly(A)-containing RNA from HeLa cells [PDF]
, 1978 The structure of the 5'-termini has been investigated in mitochondrial DNA- coded poly(A)-containing RNA from HeLa cells. For this purpose, mitochondrial RNA isolated from cells labeled for 3 hours with [32P]orthophosphate in the presence of 20 µg/ml ...
Amalric, François +3 more
core +1 more source
Poly(adenosine diphosphate‐ribose) polymerase inhibitor combinations in first‐line metastatic castrate‐resistant prostate cancer setting: a systematic review and m
, 2023 Rashid K. Sayyid +10 more
openalex +1 more source
Effect of 3-aminobenzamide on chromosome damage in human blood lymphocytes adapted to bleomycin [PDF]
, 2017 Human blood lymphocytes, pre-treated with very low (adaptation) concentrations of bleomycin for 48 h and then exposed to a high (challenge) dose of the same agent or X-rays, became significantly less sensitive to the induction of chromosome damage than ...
Burkart, W., Vijayalaxmi,,
core
Visualization of poly(ADP-ribose) bound to PARG reveals inherent balance between exo- and endo-glycohydrolase activities [PDF]
, 2013 Poly-ADP-ribosylation is a post-translational modification that regulates processes involved in genome stability. Breakdown of the poly(ADP-ribose) (PAR) polymer is catalysed by poly(ADP-ribose) glycohydrolase (PARG), whose endo-glycohydrolase activity ...
Ahel, Ivan +10 more
core +2 more sources
Lexicon for Clonal Hematopoiesis in Liquid Biopsy
Clinical and Translational Science, Volume 19, Issue 1, January 2026.ABSTRACT Historically, clonal hematopoiesis (CH) has been recognized as a confounder of cell‐free DNA (cfDNA) testing. Recent evidence now demonstrates the role of CH as a risk factor in health, generating distinct sources of cfDNA that can be leveraged for liquid biopsy diagnostics.
Robert Tell +21 more
wiley +1 more source
The FEBS Journal, Volume 293, Issue 2, Page 492-513, January 2026.Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone +4 more
wiley +1 more source