Results 31 to 40 of about 271,223 (294)

Purine and purinergic receptors

Brain and Neuroscience Advances, 2018
Adenosine 5′-triphosphate acts as an extracellular signalling molecule (purinergic signalling), as well as an intracellular energy source. Adenosine 5′-triphosphate receptors have been cloned and characterised. P1 receptors are selective for adenosine, a
Geoffrey Burnstock
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ATP as a presynaptic modulator [PDF]

, 2000
© 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy,
Cunha, Rodrigo A., Ribeiro, J. A.
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Adenosine A2A Receptor Modulates the Activity of Globus Pallidus Neurons in Rats

Frontiers in Physiology, 2017
The globus pallidus is a central nucleus in the basal ganglia motor control circuit. Morphological studies have revealed the expression of adenosine A2A receptors in the globus pallidus.
Hui-Ling Diao, Hui-Ling Diao, Yan Xue, Xiao-Hua Han, Shuang-Yan Wang, Shuang-Yan Wang, Cui Liu, Wen-Fang Chen, Lei Chen   +8 more
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Adenosine A2A receptor modulation of hippocampal CA3-CA1 synapse plasticity during associative learning in behaving mice [PDF]

, 2009
© 2009 Nature Publishing Group All rights reservedPrevious in vitro studies have characterized the electrophysiological and molecular signaling pathways of adenosine tonic modulation on long-lasting synaptic plasticity events, particularly for
A de Mendonça, A de Mendonça, A Gruart, A Gruart, A Monopoli, Agnès Gruart, AM Sebastião, AM Thomson, Ana M Sebastião, BM Fontinha, Bruno M Fontinha, C Zocchi, CC Fernandes, CD Woody, CS Rex, DKJE von Lubitz, E Dominguez-del-Toro, E Porras-García, ER Kandel, F Engert, F Suzuki, FS Lee, G Burnstock, G Neves, G Paxinos, GG Turrigiano, HJ Normile, I Gureviciene, I Sahún, JA Ribeiro, JE Kelsey, JM Delgado-Garcia, Joaquim A Ribeiro, José M Delgado-García, JR Whitlock, K Kessey, K Kessey, K Takatsuki, L Boulanger, L Connole, L Winsky, M de Jonge, M El Yacoubi, M El Yacoubi, M Ohno, M Yang, MJ Diógenes, MJ Diógenes, MT Tebano, MT Tebano, N Madroñal, N Rebola, Noelia Madroñal, O Dall'Igna, PA Schwartzkroin, RF Thompson, RS Zucker, S Ferré, S Maren, S Mingote, SR Kopf, T Sakamoto, TV Bliss, TVP Bliss, W Tseng, Y Kishimoto, Y Kishimoto, Y Sekino, Y Wang   +68 more
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Lack of endogenous adenosine tonus on sympathetic neurotransmission in spontaneously hypertensive rat mesenteric artery.

PLoS ONE, 2014
BackgroundIncreased sympathetic activity has been implicated in hypertension. Adenosine has been shown to play a role in blood flow regulation. In the present study, the endogenous adenosine neuromodulatory role, in mesenteric arteries from normotensive ...
Joana Beatriz Sousa, Maria Sofia Vieira-Rocha, Carlos Sá, Fátima Ferreirinha, Paulo Correia-de-Sá, Paula Fresco, Carmen Diniz   +6 more
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Pharmacology of the Adenosine A3 Receptor in the Vasculature and Essential Hypertension. [PDF]

PLoS ONE, 2016
BACKGROUND:Essential hypertension is considered to be a multifactorial disorder and its aetiology has yet to be clearly identified. As the adenosine receptors have a significant role in mediating vasodilation, alterations in their structures or ...
Ming-Fen Ho, Leanne M Low, Roselyn B Rose'Meyer   +2 more
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Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components [PDF]

, 1993
Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region.
Alzheimer, Alzheimer, Alzheimer, Alzheimer, Andreasen, Arai, Ault, Ault, B. Sutor, Bauer, Beavo, Beavo, Ben-Ari, Bruns, Bruns, C. Alzheimer, Chamberlin, Daly, Dragunow, Dragunow, Dunwiddie, Dunwiddie, Dunwiddie, Fredholm, G. Ten Bruggencate, Gerber, Greene, Greene, Haas, Hablitz, Hablitz, Jackisch, Johnston, Linden, Linden, Llinás, Lohse, Madison, Malenka, Meghji, Miles, Moraidis, Nicholson, Pockett, Prestwich, Prince, Scholz, Schubert, Schubert, Smellie, Smellie, Smith, Snyder, Snyder, Sutor, Tanaka, Thompson, Thompson, Van Calker, Williams, Zetterström   +60 more
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Activity-dependent release of Adenosine: a critical re-evaluation of mechanism [PDF]

, 2008
Adenosine is perhaps the most important and universal modulator in the brain. The current consensus is that it is primarily produced in the extracellular space from the breakdown of previously released ATP.
Wall, Mark J., Dale, Nicholas
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Caffeine. cognitive and physical performance enhancer or psychoactive drug? [PDF]

, 2015
Caffeine use is increasing worldwide. The underlying motivations are mainly concentration and memory enhancement and physical performance improvement. Coffee and caffeine-containing products affect the cardiovascular system, with their positive inotropic
Aromatario, Mariarosaria, Cappelletti, Simone, Piacentino, Daria, Sani, Gabriele   +3 more
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ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Adenosine Stimulates Glutamate Release From Astrocytes via A2a Adenosine Receptors

Journal of Pharmacological Sciences, 2004
Adenosine enhanced intracellular Ca2+ concentrations in astrocytes via A2a adenosine receptors involving protein kinase A (PKA) activation. The Ca2+ rise is inhibited by brefeldin A, an inhibitor of vesicular transport; but not by neomycin and U73122 ...
Tomoyuki Nishizaki
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