Results 1 to 10 of about 240,878 (357)

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

Nature, 2020
Adipose tissue is usually classified on the basis of its function as white, brown or beige (brite) 1 . It is an important regulator of systemic metabolism, as shown by the fact that dysfunctional adipose tissue in obesity leads to a variety of secondary ...
Wenfei Sun, Hua Dong, Miroslav Balaz
exaly   +2 more sources

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?

Cell Death and Differentiation, 2016
Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered in bone marrow, are multipotent cells capable of differentiating into mature cells of several mesenchymal tissues, such as fat and bone.
Q. Chen, P. Shou, C. Zheng, M. Jiang, G. Cao, Q. Yang, J. Cao, N. Xie, T. Velletri, X. Zhang, C. Xu, L. Zhang, H. Yang, J. Hou, Y. Wang, Y. Shi   +15 more
exaly   +2 more sources

A lipase-independent pathway of lipid release and immune modulation by adipocytes

Science, 2019
Exosomes that fatten immune cells Adipose tissue in mammals contains not only adipocytes (fat cells) but also a variety of immune cells—most notably, macrophages.
Stephen E Flaherty, Alireza Nomani, Anthony W Ferrante   +2 more
exaly   +2 more sources

Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics

Nature Reviews Endocrinology, 2021
Pauline Morigny, Jeremie Boucher, Peter Arner   +2 more
exaly   +2 more sources

Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues

Nature Communications, 2015
Marrow adipose tissue (MAT) accumulates in diverse clinical conditions but remains poorly understood. Here we show region-specific variation in MAT adipocyte development, regulation, size, lipid composition, gene expression and genetic determinants ...
Erica L Scheller, William P Cawthorn, Miriam A Bredella   +2 more
exaly   +2 more sources

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ

Nature, 2004
Rita Machado de Oliveira, Mark Leid
exaly   +2 more sources

Adipocytes as regulators of energy balance and glucose homeostasis

Nature, 2006
Evan D Rosen, Bruce M Spiegelman
exaly   +2 more sources

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Cell, 2012
Jun Wu, Lauren M Sparks, Pirjo Nuutila
exaly   +2 more sources

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

Nature Medicine, 2011
Kristin M Nieman, Hilary A Kenny, Iris L Romero   +2 more
exaly   +2 more sources

Immune Cell Regulation of White Adipose Progenitor Cell Fate

Frontiers in Endocrinology, 2022
Adipose tissue is essential for energy storage and endocrine regulation of metabolism. Imbalance in energy intake and expenditure result in obesity causing adipose tissue dysfunction.
Irem Altun, Irem Altun, Xiaocheng Yan, Xiaocheng Yan, Siegfried Ussar, Siegfried Ussar, Siegfried Ussar   +6 more
doaj   +1 more source