Immune Cell Regulation of White Adipose Progenitor Cell Fate
Frontiers in Endocrinology, 2022 Adipose tissue is essential for energy storage and endocrine regulation of metabolism. Imbalance in energy intake and expenditure result in obesity causing adipose tissue dysfunction.
Irem Altun +6 more
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Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population
Nature Communications, 2021 Adipose tissue is composed of a variety of cell types, including adipocyte precursor populations, that contribute to adipose tissue function upon differentiation. Here, using scRNA-sequencing of adolescent and adult mouse subcutaneous adipose tissue, the
Lisa Suwandhi +20 more
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Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice
BMC Biology, 2023 Background Biological aging is an important factor leading to the development of pathologies associated with metabolic dysregulation, including type 2 diabetes, cancer, cardiovascular and neurodegenerative diseases.
Xue Liu +10 more
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Frontiers in Cell and Developmental Biology, 2022 Abdominal obesity associates with cardiometabolic disease and an accumulation of lipids in the visceral adipose depot, whereas lipid accumulation in the subcutaneous depot is more benign.
Neha Mathur +12 more
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Fluorescent redox-dependent labeling of lipid droplets in cultured cells by reduced phenazine methosulfate [PDF]
Heliyon, volume 6, pages e04182, 2020, 2021 Natural and synthetic phenazines are widely used in biomedical sciences. In dehydrogenase histochemistry, phenazine methosulfate (PMS) is applied as a redox reagent for coupling reduced coenzymes to the reduction of tetrazolium salts into colored formazans.
arxiv +1 more source
Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice. [PDF]
PLoS ONE, 2013 Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura +6 more
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Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming [PDF]
, 2017 BACKGROUND: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in
Czech, Michael P +11 more
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AMP-Activated Kinase (AMPK) Activation by AICAR in Human White Adipocytes Derived from Pericardial White Adipose Tissue Stem Cells Induces a Partial Beige-Like Phenotype. [PDF]
PLoS ONE, 2016 Beige adipocytes are special cells situated in the white adipose tissue. Beige adipocytes, lacking thermogenic cues, morphologically look quite similar to regular white adipocytes, but with a markedly different response to adrenalin.
Omar Abdul-Rahman +18 more
doaj +1 more source
Integrin αV Mediates the Effects of Irisin on Human Mature Adipocytes
Obesity Facts, 2022 Introdution and Aims: The myokine irisin is critical to modulating adipocytes thermogenesis and influence whole-body metabolism. However, whether there is difference in the effects of irisin on adipocytes derived from different depots remains unknown ...
Tingting Fu +6 more
doaj +1 more source
Identification of Biochemical Differences in White and Brown Adipocytes Using FTIR Spectroscopy
Applied Sciences, 2022 This study was conducted to investigate the developmental characteristics of adipocytes and to identify selectively white and brown adipocytes through Fourier transform infrared (FTIR) spectroscopy.
DongHyun Shon +3 more
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