Erianin inhibits 3T3-L1 adipocyte differentiation through downregulation of CCAAT-enhancer binding protein-α and peroxisome proliferator-activated receptor-γ, lipogenic genes and impairment of mitochondrial respiration [PDF]
AdipocyteErianin, a natural bibenzyl compound, has recently garnered attention owing to its diverse biological activities. In the present study, we investigated the effects of Erianin on adipocyte differentiation, lipid metabolism, and mitochondrial respiration ...
Hathaichanok Yimpreeda +5 more
doaj +2 more sources
Adipocytes as regulators of energy balance and glucose homeostasis
Nature, 2006 Evan D Rosen, Bruce M Spiegelman
exaly +3 more sources
Immune Cell Regulation of White Adipose Progenitor Cell Fate
Frontiers in Endocrinology, 2022 Adipose tissue is essential for energy storage and endocrine regulation of metabolism. Imbalance in energy intake and expenditure result in obesity causing adipose tissue dysfunction.
Irem Altun +6 more
doaj +1 more source
Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population
Nature Communications, 2021 Adipose tissue is composed of a variety of cell types, including adipocyte precursor populations, that contribute to adipose tissue function upon differentiation. Here, using scRNA-sequencing of adolescent and adult mouse subcutaneous adipose tissue, the
Lisa Suwandhi +20 more
doaj +1 more source
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis
Molecular Metabolism, 2021 Objective: Reorganization of the extracellular matrix is a prerequisite for healthy adipose tissue expansion, whereas fibrosis is a key feature of adipose dysfunction and inflammation.
Francisco Javier Ruiz-Ojeda +15 more
doaj +1 more source
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice
BMC Biology, 2023 Background Biological aging is an important factor leading to the development of pathologies associated with metabolic dysregulation, including type 2 diabetes, cancer, cardiovascular and neurodegenerative diseases.
Xue Liu +10 more
doaj +1 more source
PAT2 regulates vATPase assembly and lysosomal acidification in brown adipocytes
Molecular Metabolism, 2022 Objective: Brown adipocytes play a key role in maintaining body temperature as well as glucose and lipid homeostasis. However, brown adipocytes need to adapt their thermogenic activity and substrate utilization to changes in nutrient availability ...
Jiefu Wang +9 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Abdominal obesity associates with cardiometabolic disease and an accumulation of lipids in the visceral adipose depot, whereas lipid accumulation in the subcutaneous depot is more benign.
Neha Mathur +12 more
doaj +1 more source
Oral Fibrolipoma Arising from Maxillary Alveolus: A Rare Case Entity [PDF]
Journal of Clinical and Diagnostic Research, 2022 Lipoma is a non malignant tumour of adipocytes. Lipomas are most commonly seen during 4th to 6th decades of life. About 20% lipomas are seen in head and neck region of which only 1-4% have been reported in oral cavity.
Shreyas N Shah +3 more
doaj +1 more source
Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice. [PDF]
PLoS ONE, 2013 Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura +6 more
doaj +1 more source