Results 1 to 10 of about 352,221 (407)
UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes
Frontiers in Endocrinology, 2020 Mammals have two types of thermogenic adipocytes: brown adipocytes and beige adipocytes. Thermogenic adipocytes express high levels of uncoupling protein 1 (UCP1) to dissipates energy in the form of heat by uncoupling the mitochondrial proton gradient ...
K. Ikeda, Tetsuya Yamada
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snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis
Nature, 2020 Adipose tissue is usually classified on the basis of its function as white, brown or beige (brite) 1 . It is an important regulator of systemic metabolism, as shown by the fact that dysfunctional adipose tissue in obesity leads to a variety of secondary ...
Wenfei Sun, Hua Dong, Miroslav Balaz
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Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocytes. [PDF]
bioRxiv, 2019 Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types in the metabolic response to IL10 remain to ...
Ahn, In Sook +15 more
core +3 more sources
Nature Communications, 2015 Marrow adipose tissue (MAT) accumulates in diverse clinical conditions but remains poorly understood. Here we show region-specific variation in MAT adipocyte development, regulation, size, lipid composition, gene expression and genetic determinants ...
Erica L Scheller +2 more
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Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics
Nature Reviews Endocrinology, 2021 Pauline Morigny +2 more
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Low-Dose Bisphenol-A Impairs Adipogenesis and Generates Dysfunctional 3T3-L1 Adipocytes
PLoS ONE, 2016 Environmental endocrine disruptors (EDCs), including bisphenol-A (BPA), have been recently involved in obesity and diabetes by dysregulating adipose tissue function.
Francesco Oriente +2 more
exaly +2 more sources
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
Nature, 2004 Rita Machado de Oliveira, Mark Leid
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Adipocytes as regulators of energy balance and glucose homeostasis
Nature, 2006 Evan D Rosen, Bruce M Spiegelman
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Immune Cell Regulation of White Adipose Progenitor Cell Fate
Frontiers in Endocrinology, 2022 Adipose tissue is essential for energy storage and endocrine regulation of metabolism. Imbalance in energy intake and expenditure result in obesity causing adipose tissue dysfunction.
Irem Altun +6 more
doaj +1 more source
Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population
Nature Communications, 2021 Adipose tissue is composed of a variety of cell types, including adipocyte precursor populations, that contribute to adipose tissue function upon differentiation. Here, using scRNA-sequencing of adolescent and adult mouse subcutaneous adipose tissue, the
Lisa Suwandhi +20 more
doaj +1 more source