Results 101 to 110 of about 39,170 (208)
Scientific Reports, 2017 We previously reported brown adipocytes can proliferate even after differentiation. To test the involvement of mature adipocyte proliferation in cell number control in fat tissue, we generated transgenic (Tg) mice over-expressing cell-cycle inhibitory ...
Yuko Okamatsu-Ogura +8 more
doaj +1 more source
Physiologically-induced adipocyte browning
Postępy Higieny i Medycyny Doświadczalnej, 2018 The data consistently suggests that expansion and activation of beige/brite adipose tissue may possibly serve as a novel cure for obesity and obesity-related complications. Interestingly, besides well-known agents affecting adipocyte transformation, such as cold-induced sympathetic stimulation, the vast majority of biological systems (e.g ...
Oskar Wojciech Wiśniewski +2 more
openaire +1 more source
Norepinephrine dependent inhibition of proteolysis in brown adipocytes [PDF]
, 2002 Brown adipose tissue (BAT) is specialized for heat production. Brown adipocytes contain an uncoupling protein (UCP-1) in the mitochondria, which uncouples oxidative phosphorylation and produces heat.
Moazed, Bita
core
, 2018 Adipocytes are lipid-rich parenchymal cells contained in a very plastic organ, whose composition can undergo striking physiologic changes. In standard conditions the organ contains white and brown adipocytes which play opposite roles: lipid storage to ...
Cinti, Saverio
core +1 more source
C5aR1-positive adipocytes mediate non-shivering thermogenesis in neonatal mice
iScienceSummary: Brown adipose tissue (BAT) plays an important role in maintaining body temperature in newborn mammals; however, its mechanisms remain poorly understood.
Huan-Yu Wang +8 more
doaj +1 more source
Scientific Reports, 2017 The epidemic of obesity and diabetes has markedly spurred the research interest in adipocyte biology. Brown adipocytes are specialized for energy expenditure and of therapeutic interest for treatment of metabolic diseases, but how brown adipocytes are ...
David W. Reid +4 more
doaj +1 more source
Mycobacterium canettii Infection of Adipose Tissues
Frontiers in Cellular and Infection Microbiology, 2017 Adipose tissues were shown to host Mycobacterium tuberculosis which is persisting inside mature adipocytes. It remains unknown whether this holds true for Mycobacterium canettii, a rare representative of the M.
Fériel Bouzid +7 more
doaj +1 more source
p38s regulate respiratory capacity of brown adipocytes. [PDF]
, 2018 Primary adipocytes isolated from intercapsular BAT were differentiated in vitro. (A) qRT-PCR analysis of browning genes mRNA expression from primary adipocytes isolated from WT or p38δ−/− mice.
Guadalupe Sabio (5487935) +21 more
core +1 more source
Evidence of mature adipocyte proliferation regulated by proliferin [PDF]
, 2010 Despite much research, whether mature adipocytes proliferate remains controversial. Here, we examined 5-bromo-2′-deoxyuridine (BrdU)-labelling of mature adipocytes.
Kazuo Kajita +16 more
core +1 more source
ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes. [PDF]
, 2014 White, beige, and brown adipocytes are developmentally and functionally distinct but often occur mixed together within individual depots. To target white, beige, and brown adipocytes for diagnostic or therapeutic purposes, a better understanding of the ...
Lee, K.Y. +12 more
core +1 more source