Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies [PDF]
, 2013 Overweight and obesity are major problems of public health in many countries worldwide. Overweight can cause severe diseases such as type II diabetes mellitus, hypertension, stroke, heart failure and several types of cancer.
Hirzel, Estelle
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Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo
Molecular Metabolism, 2017 Objective: Previous work has suggested that white adipocytes may also show a mammary luminal secretory cell phenotype during lactation. The capacity of brown and beige/brite adipocytes to display a mammary cell phenotype and the levels at which they ...
Li Li +8 more
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Control of murine brown adipocyte development by GATA6
Developmental Cell, 2023 Brown adipose tissue (BAT) is a thermogenic organ that protects animals against hypothermia and obesity. BAT derives from the multipotent paraxial mesoderm; however, the identity of embryonic brown fat progenitor cells and regulators of adipogenic commitment are unclear.
Seoyoung Jun +10 more
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Brown and Beige Adipocytes: Effects of Inflammation and Nutritional Intervention [PDF]
, 2015 Recent findings of brown adipocytes and brown-like or beige adipocytes, capable of dissipating energy as heat, in adult humans have promised new hope for obesity treatment and prevention. Understanding of the regulation of brown and beige adipocytes will
Bae, Jiyoung
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Binding test of selected aptamers toward primary brown adipocytes. [PDF]
, 2014 A. Primary brown preadipocytes were induced to differentiate into mature brown adipocytes. The differentiation process was monitored by staining with Oil-Red-O. B.
Bong Hyun Chung (566655) +7 more
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PPAR Research, 2018 GPR43, a G-protein coupled receptor recognizing short-chain fatty acids, has been reported to participate in many biological functions of white adipocytes, such as adipogenesis and lipolysis.
Jiamiao Hu +5 more
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Shades of brown: an introduction for the special focus issue of Adipocyte on “brown and beige/brite adipocytes” [PDF]
Adipocyte, 2016 The re-discovery of brown adipose tissue in humans has re-kindled enormous interest in the research of brown, and its related brown-like adipocytes, i.e., beige or brite adipocytes.
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MicroRNA networks regulate development of brown adipocytes [PDF]
Trends in Endocrinology & Metabolism, 2013 Brown adipose tissue (BAT) is specialized for heat generation and energy expenditure as a defense against cold and obesity; in both humans and mice increased amounts of BAT are associated with a lean phenotype and resistance to development of the metabolic syndrome and its complications.
Trajkovski, Mirko, Lodish, Harvey
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Histone acetylation modulates uncoupling protein1 expression in brown adipocytes [PDF]
, 2014 Uncoupling protein 1 (UCP1) is a classical feature of brown adipocytes and understanding its regulatory mechanism will help in the development of a pharmacological approach for obesity and associated metabolic diseases.
Rajan, Anubama
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Comparative secretome analyses of primary murine white and brown adipocytes reveal novel adipokines. [PDF]
, 2018 The adipose organ, including white and brown adipose tissues, is an important player in systemic energy homeostasis, storing excess energy in form of lipids while releasing energy upon various energy demands.
Herzig, S. +14 more
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