Results 11 to 20 of about 160,546 (318)

AMP-Activated Kinase (AMPK) Activation by AICAR in Human White Adipocytes Derived from Pericardial White Adipose Tissue Stem Cells Induces a Partial Beige-Like Phenotype. [PDF]

PLoS ONE, 2016
Beige adipocytes are special cells situated in the white adipose tissue. Beige adipocytes, lacking thermogenic cues, morphologically look quite similar to regular white adipocytes, but with a markedly different response to adrenalin.
Omar Abdul-Rahman, Endre Kristóf, Quang-Minh Doan-Xuan, András Vida, Lilla Nagy, Ambrus Horváth, József Simon, Tamás Maros, István Szentkirályi, Lehel Palotás, Tamás Debreceni, Péter Csizmadia, Tamás Szerafin, Tamás Fodor, Magdolna Szántó, Attila Tóth, Borbála Kiss, Zsolt Bacsó, Péter Bai   +18 more
doaj   +1 more source

Adipocytes [PDF]

Current Biology, 2014
SummaryIn the United States alone, one-third of adults and nearly one-quarter of children are clinically obese. This growing epidemic is of serious concern as obesity confers a significant risk to developing numerous chronic conditions, including cancer, diabetes, and heart disease. The alarming incidence of obesity and the rising costs of treating the
openaire   +2 more sources

PPARs and adipocyte function [PDF]

Molecular and Cellular Endocrinology, 2010
For long viewed as passive lipid storage depots, adipocytes are now recognised as key players in the pathogenesis of insulin resistance and metabolic disease. In parallel, the last two decades of research have seen the emergence of transcription factors of the peroxisome proliferator-activated receptor (PPAR) family as central regulators of lipid and ...
Christodoulides, Constantinos, Vidal-Puig, Antonio   +1 more
openaire   +5 more sources

Hair Graying Regulators Beyond Hair Follicle

Frontiers in Physiology, 2022
Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen, Jing Chen, Yixin Zheng, Chen Hu, Xuexiao Jin, Xiaoping Chen, Ying Xiao, Chaochen Wang, Chaochen Wang   +8 more
doaj   +1 more source

Hyperspectral Absorption Microscopy Using Photoacoustic Remote Sensing [PDF]

, 2021
An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing detection architecture. A wide range of photoacoustic excitation wavelengths ranging from 210 nm to 1550 nm was provided by a nanosecond tunable source allowing access to ...
arxiv   +1 more source

Role of adipocyte-derived lipoprotein lipase in adipocyte hypertrophy [PDF]

Nutrition & Metabolism, 2007
A major portion of available fatty acids for adipocyte uptake is derived from lipoprotein lipase (LPL)-mediated hydrolysis of circulating lipoprotein particles. In vivo studies aimed at identifying the precise role of adipocyte-derived LPL in fat storage function of adipose tissue have been unable to provide conclusive evidence due to compensatory ...
Amanda M Gonzales, Robert A. Orlando
openaire   +4 more sources

Extracellular calcium modulates brown adipocyte differentiation and identity

Scientific Reports, 2017
Brown adipocytes are important in regulating non-shivering thermogenesis, whole body glucose and lipid homeostasis. Increasing evidence supports an important role of metabolites as well as macro- and micronutrients in brown adipocyte differentiation and ...
Ines Pramme-Steinwachs, Martin Jastroch, Siegfried Ussar   +2 more
doaj   +1 more source

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

BMC Cancer, 2020
Background Cancer cells cooperate with cells that compose their environment to promote tumor growth and invasion. Among them, adipocytes provide lipids used as a source of energy by cancer cells and adipokines that contribute to tumor expansion ...
Martin Paré, Cédric Y. Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux   +10 more
doaj   +1 more source

Egr1 plays a major role in the transcriptional response of white adipocytes to insulin and environmental cues

Frontiers in Cell and Developmental Biology, 2022
It is believed that insulin regulates metabolic functions of white adipose tissue primarily at the post-translational level via the PI3K-Akt-mediated pathway. Still, changes in transcription also play an important role in the response of white adipocytes
A. B. Meriin, N. Zaarur, D. Roy, K. V. Kandror   +3 more
doaj   +1 more source

Transferrin Receptor Functionally Marks Thermogenic Adipocytes

Frontiers in Cell and Developmental Biology, 2020
BackgroundThermogenic adipocytes, including beige and brown adipocytes, are critical for thermogenesis and energy homeostasis. Identification of functional cell surface markers of thermogenic adipocytes is of significance for potential application in ...
Jin Qiu, Zhiyin Zhang, Sainan Wang, Yanru Chen, Caizhi Liu, Sainan Xu, Dongmei Wang, Junlei Su, Mengshan Ni, Jian Yu, Xiangdi Cui, Lu Ma, Tianhui Hu, Yepeng Hu, Xuejiang Gu, Xinran Ma, Xinran Ma, Jiqiu Wang, Lingyan Xu   +18 more
doaj   +1 more source