Results 21 to 30 of about 173,125 (313)

Cancer cell-derived exosomal miR-425-3p induces white adipocyte atrophy

Adipocyte, 2022
White adipose tissue wasting plays a critical role in the development and progression of cancer cachexia. However, the mechanism behind the loss of adipose tissue remains ill-defined.
Anwen Liu, Wenxia Pan, Shutong Zhuang, Yuanzhi Tang, Haitao Zhang   +4 more
doaj   +1 more source

Transferrin Receptor Functionally Marks Thermogenic Adipocytes

Frontiers in Cell and Developmental Biology, 2020
BackgroundThermogenic adipocytes, including beige and brown adipocytes, are critical for thermogenesis and energy homeostasis. Identification of functional cell surface markers of thermogenic adipocytes is of significance for potential application in ...
Jin Qiu, Zhiyin Zhang, Sainan Wang, Yanru Chen, Caizhi Liu, Sainan Xu, Dongmei Wang, Junlei Su, Mengshan Ni, Jian Yu, Xiangdi Cui, Lu Ma, Tianhui Hu, Yepeng Hu, Xuejiang Gu, Xinran Ma, Xinran Ma, Jiqiu Wang, Lingyan Xu   +18 more
doaj   +1 more source

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

BMC Cancer, 2020
Background Cancer cells cooperate with cells that compose their environment to promote tumor growth and invasion. Among them, adipocytes provide lipids used as a source of energy by cancer cells and adipokines that contribute to tumor expansion ...
Martin Paré, Cédric Y. Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux   +10 more
doaj   +1 more source

Regulatory mechanism of white adipocyte browning and research advances [PDF]

BIO Web of Conferences
Adipose tissue has energy storage and metabolic functions, and its content is highly correlated with an individual’s obesity status. The relative proportions of white adipocytes, brown adipocytes, and beige adipocytes are also important in regulating ...
Wang Zihan
doaj   +1 more source

Bone marrow adipocytes [PDF]

Adipocyte, 2017
Adipocytes were identified in human bone marrow more than a century ago, yet until recently little has been known about their origin, development, function or interactions with other cells in the bone marrow. Little functional significance has been attributed to these cells, a paradigm that still persists today. However, we now know that marrow adipose
Mark C, Horowitz, Ryan, Berry, Brandon, Holtrup, Zachary, Sebo, Tracy, Nelson, Jackie A, Fretz, Dieter, Lindskog, Jennifer L, Kaplan, Gene, Ables, Matthew S, Rodeheffer, Clifford J, Rosen   +10 more
openaire   +2 more sources

Adipocytes Directly Affect Coronary Artery Disease Pathogenesis via Induction of Adipokine and Cytokine Imbalances

Frontiers in Immunology, 2019
This study aimed to investigate the adipokine and cytokine profiles of adipocytes from epicardial and subcutaneous adipose tissues in interconnection with the visceral adipose tissue area and the biochemical and clinical characteristics of patients with ...
Olga Gruzdeva, Olga Gruzdeva, Evgenya Uchasova, Yulia Dyleva, Daria Borodkina, Olga Akbasheva, Larisa Antonova, Vera Matveeva, Ekaterina Belik, Sergei Ivanov, Anton Sotnikov, Kirill Kozyrin, Natalia Brel, Maxim Sinitsky, Victoria Karetnikova, Victoria Karetnikova, Alexander Kokov, Evgenya Bychkova, Tamara Pecherina, Olga Barbarash, Olga Barbarash   +20 more
doaj   +1 more source

The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis

Journal of Lipid Research, 2005
This study assessed the effects of selective inhibitors of 3′,5′-cyclic nucleotide phosphodiesterases (PDEs) on adipocyte lipolysis. IC224, a selective inhibitor of type 1 phosphodiesterase (PDE1), suppressed lipolysis in murine 3T3-L1 adipocytes (69.6 ±
Peter B. Snyder, James M. Esselstyn, Kate Loughney, Sharon L. Wolda, Vincent A. Florio   +4 more
doaj   +1 more source

Effect of metformin on transcriptome and adipokinome of adipocytes of local fat deposts of patients with ischemic heart disease

Ожирение и метаболизм, 2023
BACKGROUND: The information available to date on the effect of metformin on the transcriptome and secretory capacity of adipocytes in human adipose tissue (AT) is scarce and contradictory.
Yu. A. Dyleva, O. V. Gruzdeva, E. V. Belik, D. A. Borodkina, M. Yu. Sinitskiy, S. V. Ivanov, O. L. Barbarash   +6 more
doaj   +1 more source

Growth hormone stimulates lipolysis in mice but not in adipose tissue or adipocyte culture

Frontiers in Endocrinology, 2023
The inhibitory effect of growth hormone (GH) on adipose tissue growth and the stimulatory effect of GH on lipolysis are well known, but the mechanisms underlying these effects are not completely understood.
Lidan Zhao, Honglin Jiang
doaj   +1 more source

Lipolysis in adipocytes [PDF]

The International Journal of Biochemistry & Cell Biology, 2010
Lipolysis in adipocytes, the hydrolysis of triacylglycerol (TAG) to release fatty acids (FAs) and glycerol for use by other organs, is a unique function of white adipose tissue. Lipolysis in adipocytes occurs at the surface of cytosolic lipid droplets, which have recently gained much attention as dynamic organelles integral to lipid metabolism ...
Maryam, Ahmadian, Yuhui, Wang, Hei Sook, Sul   +2 more
openaire   +2 more sources