Results 21 to 30 of about 160,546 (318)
UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes
Frontiers in Endocrinology, 2020 Mammals have two types of thermogenic adipocytes: brown adipocytes and beige adipocytes. Thermogenic adipocytes express high levels of uncoupling protein 1 (UCP1) to dissipates energy in the form of heat by uncoupling the mitochondrial proton gradient ...
Kenji Ikeda, Tetsuya Yamada
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Food and Agricultural Immunology, 2022 Under the COVID-19 pandemic, interest in immune enhancement and anti-obesity is increasing. Thus, in this study, we investigated whether Kadsura japonica fruits (KJF) exhibits immunostimulatory activity and anti-obesity activity.
Na Gyeong Geum +9 more
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Single Acquisition Label-free Histology-like Imaging with Dual Contrast Photoacoustic Remote Sensing Microscopy [PDF]
, 2021 Significance: Histopathological analysis of tissues is an essential tool for grading, staging, diagnosing and resecting cancers and other malignancies. Current histopathological techniques require substantial sample processing prior to staining with hematoxylin and eosin (H&E) dyes, to highlight nuclear and cellular morphology.
arxiv +1 more source
European Journal of Cell Biology, 2013 Adipocytes are the main constituent of adipose tissue and are considered to be a corner stone in the homeostatic control of whole body metabolism. Their primary function is to control energy balance by storing triacylglycerol in periods of energy excess and mobilizing it during energy deprivation.
Aus Tariq Ali +4 more
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eLife, 2022 Chronic obesity is correlated with severe metabolic and cardiovascular diseases as well as with an increased risk for developing cancers. Obesity is usually characterized by fat accumulation in enlarged – hypertrophic – adipocytes that are a source of ...
Christine Müller +5 more
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Weighing in on Adipocyte Precursors [PDF]
Cell Metabolism, 2014 Obesity, defined as an excessive increase in white adipose tissue (WAT), is a global health epidemic. In obesity, WAT expands by increased adipocyte size (hypertrophy) and number (hyperplasia). The location and cellular mechanisms of WAT expansion greatly affect the pathogenesis of obesity.
Ryan Berry +2 more
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Theoretical Model and Characteristics of Mitochondrial Thermogenesis [PDF]
Biophysics Reports 2018, 2017 Mitochondria of brown adipocyte (BA) are the main intracellular sites for thermogenesis, which have been targeted for therapy to reduce obesity. However, there are long-standing critique and debates about the ability of raising cellular temperature by endogenous thermogenesis.
arxiv +1 more source
Regulatory mechanism of white adipocyte browning and research advances [PDF]
BIO Web of ConferencesAdipose tissue has energy storage and metabolic functions, and its content is highly correlated with an individual’s obesity status. The relative proportions of white adipocytes, brown adipocytes, and beige adipocytes are also important in regulating ...
Wang Zihan
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Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis
Molecular Metabolism, 2021 Objective: Reorganization of the extracellular matrix is a prerequisite for healthy adipose tissue expansion, whereas fibrosis is a key feature of adipose dysfunction and inflammation.
Francisco Javier Ruiz-Ojeda +15 more
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Frontiers in Immunology, 2019 This study aimed to investigate the adipokine and cytokine profiles of adipocytes from epicardial and subcutaneous adipose tissues in interconnection with the visceral adipose tissue area and the biochemical and clinical characteristics of patients with ...
Olga Gruzdeva +20 more
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