Results 31 to 40 of about 160,546 (318)
Adipocyte, 2012 When Ron Landes approached me last summer with the idea to launch a journal dedicated to adipose tissue research, it resonated immediately; I loved the idea. Thus, it is with great pleasure that we launch Adipocyte, the first international peer-reviewed multi-disciplinary journal to focus exclusively on research covering all aspects of adipose tissue ...
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PAT2 regulates vATPase assembly and lysosomal acidification in brown adipocytes
Molecular Metabolism, 2022 Objective: Brown adipocytes play a key role in maintaining body temperature as well as glucose and lipid homeostasis. However, brown adipocytes need to adapt their thermogenic activity and substrate utilization to changes in nutrient availability ...
Jiefu Wang +9 more
doaj
Cell Metabolism, 2010 We are pleased to present in this issue of Cell Metabolism a review series on brown adipocytes. Until recently, brown adipose tissue (BAT) was principally studied by a handful of investigators focused on rodents and newborn mammals, and, at times, their work was deemed more an exercise in scientific curiosity than an issue relevant to human health.
Charlotte Wang, Nikla Emambokus
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Adipocyte metabolism and obesity [PDF]
Journal of Lipid Research, 2009 Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity.
Alan D. Attie, Philipp E. Scherer
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Numerical analysis of a mechanotransduction dynamical model reveals homoclinic bifurcations of extracellular matrix mediated oscillations of the mesenchymal stem cell fate [PDF]
International Journal of Non-Linear Mechanics, 113, 146-157, 2019, 2019 We perform one and two-parameter numerical bifurcation analysis of a mechanotransduction model approximating the dynamics of mesenchymal stem cell differentiation into neurons, adipocytes, myocytes and osteoblasts. For our analysis, we use as bifurcation parameters the stiffness of the extracellular matrix and parameters linked with the positive ...
arxiv +1 more source
Extracting quantitative biological information from brightfield cell images using deep learning [PDF]
, 2020 Quantitative analysis of cell structures is essential for biomedical and pharmaceutical research. The standard imaging approach relies on fluorescence microscopy, where cell structures of interest are labeled by chemical staining techniques. However, these techniques are often invasive and sometimes even toxic to the cells, in addition to being time ...
arxiv +1 more source
Food Frontiers, 2022 Berry consumption shows antiobesity and antidiabetic effects in animals and humans. Anthocyanin or berry extracts increase insulin sensitivity, reduce lipid droplet formation, and cause a white‐to‐brite phenotypic switch of adipocytes in vitro.
Patrick Solverson +5 more
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Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome
Molecular Metabolism, 2016 Background: Diabetes, obesity, and the metabolic syndrome are multifactorial diseases dependent on a complex interaction of host genetics, diet, and other environmental factors.
Siegfried Ussar +2 more
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BiologyThe growing obesity epidemic necessitates increased research on adipocyte and adipose tissue function and disease mechanisms that progress obesity. Historically, adipocytes were viewed simply as storage for excess energy. However, recent studies have demonstrated that adipocytes play a critical role in whole-body homeostasis, are involved in cell ...
Sean P. Blade +4 more
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Cancer Reports, 2023 Background Peritoneal metastasis (PM) is one of the most common causes of noncurative surgery and the most frequent recurrence pattern in gastric cancer (GC).
Toshihide Hamabe‐Horiike +5 more
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