Results 31 to 40 of about 240,878 (357)

Cancer-associated adipocytes: key players in breast cancer progression

open access: yesJournal of Hematology & Oncology, 2019
Adipocytes are one of the primary stromal cells in many tissues, and they are considered to play an active role in the tumor microenvironment. Cancer-associated adipocytes (CAAs) are not only found adjacent to cancer cells, but also communicate with ...
Qi Wu   +5 more
semanticscholar   +1 more source

Role of adipocyte-derived lipoprotein lipase in adipocyte hypertrophy [PDF]

open access: yesNutrition & Metabolism, 2007
A major portion of available fatty acids for adipocyte uptake is derived from lipoprotein lipase (LPL)-mediated hydrolysis of circulating lipoprotein particles. In vivo studies aimed at identifying the precise role of adipocyte-derived LPL in fat storage function of adipose tissue have been unable to provide conclusive evidence due to compensatory ...
Amanda M Gonzales, Robert A. Orlando
openaire   +4 more sources

Transferrin Receptor Functionally Marks Thermogenic Adipocytes

open access: yesFrontiers in Cell and Developmental Biology, 2020
BackgroundThermogenic adipocytes, including beige and brown adipocytes, are critical for thermogenesis and energy homeostasis. Identification of functional cell surface markers of thermogenic adipocytes is of significance for potential application in ...
Jin Qiu   +18 more
doaj   +1 more source

Extracellular calcium modulates brown adipocyte differentiation and identity

open access: yesScientific Reports, 2017
Brown adipocytes are important in regulating non-shivering thermogenesis, whole body glucose and lipid homeostasis. Increasing evidence supports an important role of metabolites as well as macro- and micronutrients in brown adipocyte differentiation and ...
Ines Pramme-Steinwachs   +2 more
doaj   +1 more source

Small Extracellular Microvesicles Mediated Pathological Communications Between Dysfunctional Adipocytes and Cardiomyocytes as a Novel Mechanism Exacerbating Ischemia/Reperfusion Injury in Diabetic Mice

open access: yesCirculation, 2020
Supplemental Digital Content is available in the text. Background: Diabetes mellitus exacerbates myocardial ischemia/reperfusion (MI/R) injury by incompletely understood mechanisms. Adipocyte dysfunction contributes to remote organ injury.
Lu Gan   +10 more
semanticscholar   +1 more source

Acute Myeloid Leukaemia Drives Metabolic Changes in the Bone Marrow Niche

open access: yesFrontiers in Oncology, 2022
Acute myeloid leukaemia (AML) is a highly proliferative cancer characterised by infiltration of immature haematopoietic cells in the bone marrow (BM). AML predominantly affects older people and outcomes, particularly in this difficult to treat population
Rebecca S. Maynard   +5 more
doaj   +1 more source

Stromal-vascular fraction of adipose tissue as an alternative source of cellular material for regenerative medicine [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2021
Adipose tissue is the most convenient source of cellular material for regenerative medicine as it can be obtained in significant quantities via cosmetic liposuction, lipoaspiration of subcutaneous fat or by excision of fat deposits.
A. S. Sultanova   +2 more
doaj   +1 more source

Cancer-associated adipocytes: emerging supporters in breast cancer

open access: yesJournal of experimental & clinical cancer research : CR, 2020
Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis and recurrence rate, and adipocytes are the largest components in breast tissue.
Chongru Zhao   +8 more
semanticscholar   +1 more source

Adipocyte and adipogenesis

open access: yesEuropean Journal of Cell Biology, 2013
Adipocytes are the main constituent of adipose tissue and are considered to be a corner stone in the homeostatic control of whole body metabolism. Their primary function is to control energy balance by storing triacylglycerol in periods of energy excess and mobilizing it during energy deprivation.
Aus Tariq Ali   +4 more
openaire   +3 more sources

Synthesis of Ziziphus spina-christi (Jujube) Root Methanol Extract Loaded Functionalized Silver Nanoparticle (ZS-Ag-NPs); Physiochemical Characterization and Effect of ZS-Ag-NPs on Adipocyte Maturation, Adipokine and Vascular Smooth Muscle Cell Interaction

open access: yesNanomaterials, 2021
In this research, a simple, green approach was employed to synthesize silver nanoparticles with the aid of Ziziphus spina-christi (L.) methanol root extract, which can act as a reducing, capping agent to treat obesity and inflammation. Globally, Ziziphus
Abu ElGasim Ahmed Yagoub   +5 more
doaj   +1 more source

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