Results 181 to 190 of about 1,797,998 (215)

Fueling or Fighting Cancer? The Thermogenic Paradox of Brown Adipose Tissue. [PDF]

open access: yesCurr Obes Rep
Guerrero JJG   +9 more
europepmc   +1 more source

Maternal vitamin A deficiency suppresses browning of white adipose tissue in offspring. [PDF]

open access: yesFEBS J
Kato-Suzuki M   +6 more
europepmc   +1 more source

Brown and Beige Adipose Tissue [PDF]

open access: yesEndocrinology and Metabolism Clinics of North America, 2016
Overweight and obesity are global health problems placing an ever-increasing demand on health care systems. Brown adipose tissue (BAT) is present in significant amounts in adults. BAT has potential as a fuel for oxidation and dissipation as heat production, which makes it an attractive target for obesity therapy.
John P Kirwan, Anny Mulya
exaly   +3 more sources

Sympathetic Innervation of White Adipose Tissue: to Beige or Not to Beige?

Physiology, 2021
Obesity research progresses in understanding neuronal circuits and adipocyte biology to regulate metabolism. However, the interface of neuro-adipocyte interaction is less studied. We summarize the current knowledge of adipose tissue innervation and interaction with adipocytes and emphasize adipocyte transitions from white to brown adipocytes and vice ...
Heike Münzberg   +2 more
openaire   +2 more sources

The role of autophagy in brown and beige adipose tissue plasticity

Journal of Physiology and Biochemistry, 2019
Since the rediscovery of active brown and beige adipose tissues in humans a decade ago, great efforts have been made to identify the mechanisms underlying the activation and inactivation of these tissues, with the hope of designing potential strategies to fight against obesity and associated metabolic disorders such as type 2 diabetes.
Montse Cairo, Joan Villarroya
exaly   +3 more sources

Evaluation of markers of beige adipocytes in white adipose tissue of the mouse [PDF]

open access: yesNutrition and Metabolism, 2016
There is a growing interest in exploiting the induction of beige or "brite" (brown in white) adipocytes (beigeing) to combat obesity and its comorbidities. However, there is some uncertainty regarding the best markers to evaluate the occurrence or magnitude of beigeing in white adipose tissue in the mouse model.We evaluated the transcript expression of
James Roemmich, Kate J Claycombe
exaly   +3 more sources

Aging of Brown and Beige/Brite Adipose Tissue

2018
Brown adipose tissue aging and the concomitant loss of thermogenic capacity have been linked to an inability to maintain normal energy homeostasis in late life. Similarly, the ability of white fat to convert into brite/beige adipose tissue declines. This may ultimately exacerbate the progression of age-related metabolic pathologies, such as insulin ...
Antonia, Graja   +2 more
openaire   +2 more sources

Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes [PDF]

open access: yesJournal of Physiology and Biochemistry, 2018
Mammalian adipose tissue is traditionally categorized into white and brown relating to their function and morphology: while white serves as an energy storage, brown adipose tissue acts as the heat generator maintaining the core body temperature. The most
Tuomo Glumoff, Kaisanlahti A
exaly   +2 more sources

Transcriptome profile of white, brown and beige adipose tissue

The FASEB Journal, 2022
Adipose tissue dysregulation lies at the core metabolic syndrome. White adipose tissue (WAT) has the capacity to store energy, whereas brown adipose tissue (BAT) can dissipate energy through thermogenesis. Newly discovered beige adipocytes are brown like adipocytes recruited in WAT in response to b3‐adrenergic stimulation (CL316 ...
Henry Paz   +4 more
openaire   +1 more source

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