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Brown and Beige Adipose Tissues in Health and Disease
Comprehensive Physiology, 2017ABSTRACT Brown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue (BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat develops postnatally and is highly inducible. Beige fat recruitment is mediated by multiple mechanisms, including
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2017
The recent discovery of functional brown adipose tissue (BAT) in adults has stimulated intense interest for its therapeutic potential against obesity and its related metabolic conditions. Although rodent studies support the importance of brown and beige adipocytes in metabolic health, a smaller number of clinical investigations have examined their ...
Maria Chondronikola, Labros S. Sidossis
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The recent discovery of functional brown adipose tissue (BAT) in adults has stimulated intense interest for its therapeutic potential against obesity and its related metabolic conditions. Although rodent studies support the importance of brown and beige adipocytes in metabolic health, a smaller number of clinical investigations have examined their ...
Maria Chondronikola, Labros S. Sidossis
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Inducible brown/beige adipocytes in retro-orbital adipose tissues
Experimental Eye Research, 2019Beige adipocytes and brown adipocytes can generate heat by using mitochondrial uncoupling protein 1 (Ucp1), a thermogenic protein. Browning/beiging is the emergence of beige adipocytes in white adipose tissues (WAT) for cold acclimatization. Here we show the existence of brown/beige adipocytes in retro-orbital WAT in mice. Histologically, Ucp1-positive
Makoto, Sugiyama +6 more
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Dynamic contrast‐enhanced MRI of brown and beige adipose tissues
Magnetic Resonance in Medicine, 2019PurposeThe vascular blood flow in brown adipose tissue (BAT) is important for handling triglyceride clearance, increased blood flow and oxygenation. We used dynamic contrast‐enhanced (DCE)‐MRI and fat fraction (FF) imaging for investigating vascular perfusion kinetics in brown and beige adipose tissues with cold exposure or treatment with β3‐adrenergic
Jadegoud Yaligar +8 more
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ADIPOGENESIS FEATURES OF WHITE, BEIGE AND BROWN ADIPOSE TISSUES
BIOTECHNOLOGY: STATE OF THE ART AND PERSPECTIVES, 2021White and brown adipose tissue is present in the human body and is well described. As well as the effect of the type of fat on human health, in particular obesity, type 2 diabetes, insulin tolerance. The presence and distribution of different types of fat in pigs has not been adequately described.
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Role of developmental transcription factors in white, brown and beige adipose tissues
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015In this review we discuss the role of developmental transcription factors in adipose tissue biology with a focus on how these developmental genes may contribute to regional variation in adipose tissue distribution and function. Regional, depot-specific, differences in lipid handling and signalling (lipolysis, lipid storage and adipokine/lipokine ...
Catriona, Hilton +2 more
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Impact of Estrogens on the Regulation of White, Beige, and Brown Adipose Tissue Depots
Comprehensive Physiology, 2019ABSTRACT As adipose tissue depots are active endocrine organs, they secrete a variety of hormones (including estrogens from white adipose) and inflammatory mediators, which have important implications in numerous obesity‐associated diseases.
Gabriel B, Bernasochi +4 more
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Parkin-mediated mitophagy in beige adipose tissue
Metabolism, 2020Zihang, Wang +2 more
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Endocrine Regulation of Brown and Beige Adipose Tissue
2021Ariana Vargas-Castillo +2 more
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