Results 21 to 30 of about 170,418 (255)
AMP-activated kinase (AMPK) activation by AICAR in human white adipocytes derived from pericardial white adipose tissue stem cells induces a partial beige-like phenotype [PDF]
PLoS ONE, 2016 Beige adipocytes are special cells situated in the white adipose tissue. Beige adipocytes, lacking thermogenic cues, morphologically look quite similar to regular white adipocytes, but with a markedly different response to adrenalin.
Ambrus Horváth +18 more
core +7 more sources
Mirabegron: The most promising adipose tissue beiging agent [PDF]
Physiological Reports, 2021 Accumulation of white adipose tissue (WAT) underlies the obesity epidemic, leading to current therapeutic techniques that are being investigated for their ability to activate/"beige" this tissue. Adipose tissue (AT) beiging has been reported through intermittent cold exposure (CE), exercise, and β3-Adrenergic Receptor (β3AR) agonists.
Neelam Khaper +6 more
openaire +3 more sources
Reviews in Endocrine & Metabolic Disorders, 2023 Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT primarily stores energy, BAT dissipates energy as heat for thermoregulation.
Zeinab Ghesmati +5 more
semanticscholar +1 more source
Peptidoglycan inhibits beigeing of adipose tissue
Acta Pharmaceutica Sinica B, 2022 Abstract Obesity, an epidemic metabolic disease characterized by excessive fat accumulation, causes a significant economic burden on families and the society. The discovery of beige adipocytes has provided us with a brand new approach for the intervention of obesity 1 .
Hong Chen +6 more
openaire +4 more sources
Adipocyte, 2021 Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng +13 more
semanticscholar +1 more source
Ckmt1 is Dispensable for Mitochondrial Bioenergetics Within White/Beige Adipose Tissue
Function, 2022 Within brown adipose tissue (BAT), the brain isoform of creatine kinase (CKB) has been proposed to regulate the regeneration of ADP and phosphocreatine in a futile creatine cycle (FCC) that stimulates energy expenditure. However, the presence of FCC, and
Valerie Politis-Barber +9 more
semanticscholar +1 more source
Hydrogel-based engineering of beige adipose tissue [PDF]
Journal of Materials Chemistry B, 2015 Brown and beige adipose tissues have a significant capacity for energy expenditure that may be exploited as a treatment for obesity and metabolic disease.
Eric M. Brey +8 more
openaire +3 more sources
Beige Adipocyte As The Flame Of White Adipose Tissue: Regulation Of Browning And Impact Of Obesity.
Journal of Clinical Endocrinology and Metabolism, 2021 Beige adipocyte, the third and relatively new type of adipocyte, can emerge in white adipose tissue (WAT) under thermogenic stimulations that is termed as browning of WAT.
A. Altinova
semanticscholar +1 more source
Brown and Beige Adipose Tissue [PDF]
Endocrinology and Metabolism Clinics of North America, 2016 Overweight and obesity are global health problems placing an ever-increasing demand on health care systems. Brown adipose tissue (BAT) is present in significant amounts in adults. BAT has potential as a fuel for oxidation and dissipation as heat production, which makes it an attractive target for obesity therapy.
John P. Kirwan +3 more
openaire +3 more sources
Matrix-Assisted Transplantation of Functional Beige Adipose Tissue [PDF]
Diabetes, 2015 Novel, clinically relevant, approaches to shift energy balance are urgently needed to combat metabolic disorders such as obesity and diabetes. One promising approach has been the expansion of brown adipose tissues that express uncoupling protein (UCP) 1 and thus can uncouple mitochondrial respiration from ATP synthesis.
Tharp, Kevin M +8 more
openaire +5 more sources