Results 61 to 70 of about 1,797,998 (215)

Advances in the Protective Effects and Mechanisms of β‐Aminoisobutyric Acid in Maintaining Multi‐Organ Homeostasis

Medicine Bulletin, EarlyView.
ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang, Wen‐Bi He, Fei‐Peng Chen, Jiong‐Xing Huang, Lin Zhu, Xiao‐Guang Liu   +5 more
wiley   +1 more source

Anatomy of the Epicardial Adipose Tissue

, 2020
Epicardial adipose tissue (EAT) is the fat depot located between the myocardium and the epicardium including the surroundings of the epicardial coronary vessels while the pericardial fat is located externally.
Iacobellis, Gianluca
core   +1 more source

Characterization and Beige Adipogenic Potential of Human Embryo White Adipose Tissue-Derived Stem Cells

Cellular Physiology and Biochemistry, 2018
Background/Aims: Brown and beige adipocytes are widely recognized as potential therapeutic targets to treat obesity and related metabolic disorders, and the recruitment of brown and beige adipocytes is an essential aspect that requires attention ...
Chuanhai Zhang, Jing Jing Wang, Xiaoyun He, Chao Wang, Boyang Zhang, Jia Xu, Wentao Xu, Yunbo Luo, Kunlun Huang   +8 more
doaj   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Bone Morphogenetic Protein 4 regulates white, beige and brown adipose tissue [PDF]

, 2017
Obesity and its associated complications, including Type 2 diabetes, are increasing at an epidemic rate globally. Adipose tissue exerts different functions and is central in energy homeostasis, and it consists of white, beige or brown adipocytes.
Hoffmann, Jenny
core   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences [PDF]

, 2010
Lipoatrophy and metabolic complications of treatment of human immunodeficiency virus (HIV) infection may share common associations with adipose tissue pathology and inflammation.
McKinnon, E., Nolan, D., Hammond, E.L.
core  

A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences [PDF]

, 2010
Depot-dependent differences in adipose tissue physiology may reflect specialized functions and local interactions between adipocytes and surrounding tissues.
Kelder, T.A.J., Kooistra, Teake, MÜLLER M, Manieri, Monia, Evelo, C.T.A., Cinti, Saverio, Kelder, T., Saverio Cinti, Cinti, S., Müller, M.R., BOEKSCHOTEN M, Kelder, Thomas, MANIERI M, Manieri, M., Drevon, C.A., Evelo, C.T.A.; id_orcid, Christian A Drevon, Monia Manieri, Teake Kooistra, Chris Evelo, Boekschoten, M.V., Robert Kleemann, EVELO C, Müller, Michael, Caesar, R., KELDER T, Boekschoten, M., Christian A. Drevon, Thomas Kelder, Michael Müller, Robert Caesar, KOOISTRA T, Caesar, Robert, Kooistra, T., Kleemann, R., Robert Caesar, Michael Müller, Mark Boekschoten, Boekschoten, Mark, KLEEMANN R, Kleemann, Robert, Evelo, C., Evelo, Chris, Müller, M., DREVON CA, Drevon, Christian A., CAESAR R   +46 more
core   +3 more sources

ESRRG and PERM1 Govern Mitochondrial Conversion in Brite/Beige Adipocyte Formation

Frontiers in Endocrinology, 2020
When exposed to cold temperatures, mice increase their thermogenic capacity by an expansion of brown adipose tissue mass and the formation of brite/beige adipocytes in white adipose tissue depots.
Sebastian Müller, Sebastian Müller, Sebastian Müller, Aliki Perdikari, Dianne H. Dapito, Wenfei Sun, Bernd Wollscheid, Miroslav Balaz, Christian Wolfrum   +8 more
doaj   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source