Results 91 to 100 of about 14,567 (295)
Carbonic anhydrase 2 mediates anti-obesity effects of black tea as thermogenic activator
Food Science and Human WellnessObesity is a metabolic disorder due to over-accumulation of adipose tissue and ultimately becomes a “disease”. Brown adipose tissue (BAT) thermogenesis and white adipose tissue (WAT) browning emerge as a potential strategy of anti-obesity by dissipating ...
Peng Ma +14 more
doaj +1 more source
Endurance training promotes the browning of WAT by enhancing the NPFF pathway in the hypothalamus in rats with type 2 diabetes [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Type 2 diabetes (T2D) represents a complex and multifactorial disorder, and efforts to discover its treatment are necessary. Browning of white adipose tissue (WAT) as a therapeutic target for diabetes seems to be induced by exercise through
Syiedeh Maryam Mousavi +4 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source
Cold Induced Depot-Specific Browning in Ferret Aortic Perivascular Adipose Tissue
, 2019 Brown adipose tissue is responsible for facultative thermogenesis to produce heat and increase energy expenditure in response to proper stimuli, e.g., cold.
Keijer, Jaap +5 more
core +2 more sources
PRMT4 facilitates white adipose tissue browning and thermogenesis by methylating PPARγ
, 2023 Obesity is a global health threat, and the induction of white adipose tissue (WAT) browning presents a promising therapeutic method for it. Recent publications revealed the essential role of protein arginine methyltransferase 4 (PRMT4) in lipid ...
Shu Yan (394046) +11 more
core +1 more source
Per‐ and Polyfluoroalkyl Substances and Knee Osteoarthritis: Data From the Osteoarthritis Initiative
Arthritis &Rheumatology, EarlyView.Objective To examine whether concentrations of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS relate to incident knee osteoarthritis (KOA) and knee pain progression. Methods Among a case‐cohort sample from the OA Initiative (n = 1,878), we examined associations of serum concentrations of eight PFAS with odds of developing ...
Jeffrey B. Driban +14 more
wiley +1 more source
DEPP Deficiency Contributes to Browning of White Adipose Tissue
, 2022 Decidual protein induced by progesterone (DEPP) was originally identified as a modulator in the process of decidualization in the endometrium. Here, we define that DEPP is involved in adipose tissue thermogenesis, which contributes to metabolic ...
Ying He +15 more
core +1 more source
Humans are not unique: difficult birth is common in placental mammals
Biological Reviews, EarlyView.ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley +1 more source
Egr1 deficiency induces browning of inguinal subcutaneous white adipose tissue in mice
, 2017 Beige adipocyte differentiation within white adipose tissue, referred to as browning, is seen as a possible mechanism for increasing energy expenditure. The molecular regulation underlying the thermogenic browning process has not been entirely elucidated.
Marianne Bléher +6 more
core +1 more source
Mark4 Inhibited the Browning of White Adipose Tissue by Promoting Adipocytes Autophagy in Mice
, 2020 Autophagy can remove excess or dysfunctional proteins and organelles to maintain cellular homeostasis. Browning of white adipose tissue increases the energy expenditure.
Qian Sun +4 more
core +1 more source