Results 81 to 90 of about 14,567 (295)

Hyperactive browning and hypermetabolism: potentially dangerous element in critical illness

Frontiers in Endocrinology
Brown/beige adipose tissue has attracted much attention in previous studies because it can improve metabolism and combat obesity through non-shivering thermogenesis.
Lu Huang, Lili Zhu, Zhenxiong Zhao, Shenglu Jiang   +3 more
doaj   +1 more source

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

The Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella   +3 more
wiley   +1 more source

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning [PDF]

, 2017
White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational modifications of histones have been shown to regulate cellular energy metabolism, but their role in white
Silva, R., G. Cermenati, Cinzia Magagnotti, Andolfo, A., F. Gilardi, Emma De Fabiani, Raffaella Longo, Rui Silva, Gaia Cermenati, Maurizio Crestani, M. Crestani, Annapaola Andolfo, Magagnotti, Cinzia, Fiorino, E., Fabiani, E., Scott W. Hiebert, Desvergne, B., D. Caruso, E. Fiorino, Cermenati, G., Erika Fiorino, A. Ferrari, Federica Gilardi, Caruso, D., Donatella Caruso, Hiebert, S.W., TEIXEIRA DA SILVA, RUI GONCALO, Hiebert, Scott W., Desvergne, Béatrice, Alessandra Ferrari, R. Longo, Mitro, N., N. Mitro, Béatrice Desvergne, Longo, R., E. De Fabiani, Ferrari, A., Gilardi, F., Andolfo, Annapaola, Crestani, M., Magagnotti, C., Nico Mitro   +41 more
core   +1 more source

The 9+ month marathon: How pregnancy may have shaped human endurance capacities

The Anatomical Record, EarlyView.
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley   +1 more source

Browning of Adipose Tissue and Sirtuin1 Involvement.

, 2018
Obesity is an important risk factor for many diseases, including cardiovascular diseases, metabolic syndrome and cancers. Excessive dietary intake of caloric food results in its accumulation in white adipose tissue (WAT), whereas energy expenditure by ...
Rezzani R., Krajčíková K, Bonomini F., Favero G., Tomečková V., Rodella L. F.   +5 more
core  

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

Animal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun, Donglei Sun, Haishen Wen, Xin Qi, Chao Li, Xiaoyan Zhang, Yun Li   +6 more
wiley   +1 more source

Intermittent Fasting‐Induced Orm2 Promotes Adipose Browning via the GP130/IL23R‐p38 Cascade

Advanced Science
Intermittent fasting (IF) plays a critical role in mitigating obesity, yet the precise biological mechanisms require further elucidation. Here Orosomucoid 2 (Orm2) is identified as an IF‐induced hepatokine that stimulates adipose browning.
Xuejuan Zhu, Xinran Wang, Jingang Wang, Lei Du, Zhen‐Ning Zhang, Donglei Zhou, Junfeng Han, Bing Luan   +7 more
doaj   +1 more source

When LXA4 meets white fat: browning via the miR-133a-3p/SIRT1 pathway in mouse models

Adipocyte
Given the established positive role of Lipoxin A4 (LXA4) in adipose browning at the cellular level, this study investigated its possible effect on white fat browning and the underlying molecular mechanisms.
Dan Yu, Yuan Ruan, Yisu Wang, Xiaopei Chen, Dan Wang, Tianfeng Wu   +5 more
doaj   +1 more source

Physiological regulation and metabolic role of browning in white adipose tissue

, 2017
Great progress has been made in our understanding of the browning process in white adipose tissue (WAT) in rodents. The recognition that i) adult humans have physiologically inducible brown adipose tissue (BAT) that may facilitate resistance to obesity ...
Korać, Bato, Bato Korac, Stančić, Ana, Korać, Aleksandra, Ana Stancic, Biljana Buzadzic, Janković, Aleksandra, Vesna Otasevic, Aleksandra Korac, Otašević, Vesna, Buzadžić, Biljana, Aleksandra Jankovic   +11 more
core   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source