Adult Hippocampal Neurogenesis: A Possible Way how Physical Exercise Counteracts Stress [PDF]
Cell Transplantation, 2011 It was considered that neurogenesis only occurred during the embryonic and developmental stage. This view has greatly changed since the discovery of adult neurogenesis in two brain regions: the hippocampus and the olfactory bulb.
Suk-Yu Yau +2 more
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Multimodal insights into adult neurogenesis: An integrative review of multi-omics approaches [PDF]
HeliyonAdult neural stem cells divide to produce neurons that migrate to preexisting neuronal circuits in a process named adult neurogenesis. Adult neurogenesis is one of the most exciting areas of current neuroscience, and it may be involved in a range of ...
Jin Li +8 more
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Doxycycline increases neurogenesis and reduces microglia in the adult hippocampus. [PDF]
Frontiers in Neuroscience, 2013 Adult hippocampal neurogenesis results in the continuous formation of new neurons and is a process of brain plasticity involved in learning and memory. Although inducible-reversible transgenic mouse models are increasingly being used to investigate adult
Sebastien eSultan +2 more
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Inhibition of TGF-β signaling in microglia stimulates hippocampal adult neurogenesis and reduces anxiety-like behavior in adult mice [PDF]
Nature CommunicationsAdult neurogenesis in the subgranular zone (SGZ) has been implicated in cognitive and affective functions. The role of neuroinflammation and reactive microglia in SGZ neurogenesis is not well understood.
Kierra Ware +12 more
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The intricate interplay between microglia and adult neurogenesis in Alzheimer’s disease [PDF]
Frontiers in Cellular NeuroscienceMicroglia, the resident immune cells of the central nervous system, play a crucial role in regulating adult neurogenesis and contribute significantly to the pathogenesis of Alzheimer’s disease (AD).
Iris Früholz +4 more
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Adult neurogenesis improves spatial information encoding in the mouse hippocampus [PDF]
Nature CommunicationsAdult neurogenesis is a unique form of neuronal plasticity in which newly generated neurons are integrated into the adult dentate gyrus in a process that is modulated by environmental stimuli.
M. Agustina Frechou +7 more
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What can traditional Chinese medicine do for adult neurogenesis?
Frontiers in Neuroscience, 2023 Adult neurogenesis plays a crucial role in cognitive function and mood regulation, while aberrant adult neurogenesis contributes to various neurological and psychiatric diseases.
Wei Shen +7 more
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Frontiers in Aging Neuroscience, 2022 Alzheimer’s disease (AD) is a neurodegenerative disease that is characterized by irreversible cognitive declines. Senile plaques formed by amyloid-β (Aβ) peptides and neurofibrillary tangles, consisting of hyperphosphorylated tau protein accumulation ...
Hyeon Soo Kim +7 more
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Prenatal stress inhibits hippocampal neurogenesis but spares olfactory bulb neurogenesis. [PDF]
PLoS ONE, 2013 The dentate gyrus (DG) and the olfactory bulb (OB) are two regions of the adult brain in which new neurons are integrated daily in the existing networks.
Laure Belnoue +4 more
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HDAC1 Regulates Neuronal Differentiation
Frontiers in Molecular Neuroscience, 2022 In adult hippocampal neurogenesis, chromatin modification plays an important role in neural stem cell self-renewal and differentiation by regulating the expression of multiple genes. Histone deacetylases (HDACs), which remove acetyl groups from histones,
Vanesa Nieto-Estevez +12 more
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