Results 31 to 40 of about 152,756 (198)

Local and regional heterogeneity underlying hippocampal modulation of cognition and mood. [PDF]

, 2014
While the hippocampus has been classically studied for its role in learning and memory, there is significant support for a role of the HPC in regulating emotional behavior.
Jimenez, Jessica C, Kheirbek, Mazen A, Tannenholz, Lindsay   +2 more
core   +2 more sources

Role of adult hippocampal neurogenesis in stress resilience

Neurobiology of Stress, 2015
There is a growing appreciation that adult hippocampal neurogenesis plays a role in emotional and cognitive processes related to psychiatric disorders. Although many studies have investigated the effects of stress on adult hippocampal neurogenesis, most ...
Brunno R. Levone, John F. Cryan, Olivia F. O'Leary   +2 more
doaj   +1 more source

Molecular mechanisms of neurogenic aging in the adult mouse subventricular zone [PDF]

, 2019
In the adult rodent brain, the continuous production of new neurons by neural stem/progenitor cells (NSPCs) residing in specialized neurogenic niches and their subsequent integration into pre-existing cerebral circuitries supports odour discrimination ...
Biagioni, Stefano, Cacci, Emanuele, Gioia, Roberta, Lupo, Giuseppe, Nisi, PAOLA SERENA   +4 more
core   +1 more source

Signaling in adult neurogenesis [PDF]

Current Opinion in Neurobiology, 2010
Neural stem cells (NSCs) in the adult brain continuously supply new neurons to the hippocampal dentate gyrus (DG) and the olfactory bulb (OB). Recent studies indicate that the progression from neural precursor cells (NPCs) to mature neurons is tightly controlled by coordinate cell-intrinsic programs and external signals within the neurogenic niche.
Yangling, Mu, Star W, Lee, Fred H, Gage
openaire   +2 more sources

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. [PDF]

, 2018
New neurons continue to be generated in the subgranular zone of the dentate gyrus of the adult mammalian hippocampus. This process has been linked to learning and memory, stress and exercise, and is thought to be altered in neurological disease.
A Fahrner, AD Workman, Antonio J. Gutierrez, Arantxa Cebrian-Silla, Arnold R. Kriegstein, Arturo Alvarez-Buylla, AS Hill, B Seri, B Steiner, C Wang, CV Dennis, Dashi Qi, David James, DR Kornack, DR Kornack, E Gould, E Gould, Edward F. Chang, Eric J. Huang, G Kempermann, Gary W. Mathern, GW Mathern, H Suh, H van Praag, H van Praag, HJ Kang, J Altman, J Altman, JE Malberg, JJ Breunig, Jose Manuel Garcia-Verdugo, Julia Chang, Kadellyn Sandoval, Kevin W. Kelley, KJ Mathews, KL Spalding, Kurtis I. Auguste, M Komitova, M Venere, Mercedes F. Paredes, MF Eckenhoff, Michael C. Oldham, N Patzke, N Sanai, P Yang, PS Eriksson, R Knoth, S Lugert, Shawn F. Sorrells, Simone Mayer, T Sugiyama, TE Bakken, Y Zhang, Zhengang Yang   +53 more
core   +1 more source

Dopamine and adult neurogenesis [PDF]

Journal of Neurochemistry, 2006
AbstractDopamine is an important neurotransmitter implicated in the regulation of mood, motivation and movement. We have reviewed here recent data suggesting that dopamine, in addition to being a neurotransmitter, also plays a role in the regulation of endogenous neurogenesis in the adult mammalian brain. In addition, we approach a highly controversial
Andreas, Borta, Günter U, Höglinger
openaire   +2 more sources

Genetic Methods to Identify and Manipulate Newly born Neurons in the Adult Brain

Frontiers in Neuroscience, 2011
Although mammalian neurogenesis is mostly completed by the perinatal period, new neurons are continuously generated in the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus.
Itaru eImayoshi, Masayuki eSakamoto, Ryoichiro eKageyama   +2 more
doaj   +1 more source

Adult Olfactory Bulb Neurogenesis [PDF]

Cold Spring Harbor Perspectives in Biology, 2016
Most organisms use their olfactory system to detect and analyze chemical cues from the external world to guide essential behaviors. From worms to vertebrates, chemicals are detected by odorant receptors expressed by olfactory sensory neurons, which in vertebrates send an axon to the primary processing center called the olfactory bulb (OB).
Pierre-Marie, Lledo, Matt, Valley
openaire   +2 more sources

What do we know about adult mammalian hippocampal neurogenesis so far? [PDF]

Medicinski Podmladak
It is known that the adult mammalian brain can add new neurons throughout the whole lifespan. Neural stem cells reside in the subgranular zone of the dentate gyrus of the hippocampus and the subventricular zone of the rostral lateral ventricle.
Jeremić Rada, Brkić Predrag, Dacić Sanja   +2 more
doaj   +1 more source

Modeling Reveals the Dependence of Hippocampal Neurogenesis Radiosensitivity on Age and Strain of Rats [PDF]

, 2018
Cognitive dysfunction following radiation treatment for brain cancers in both children and adults have been correlated to impairment of neurogenesis in the hippocampal dentate gyrus.
Cacao, Eliedonna, Cucinotta, Francis A., Kapukotuwa, Sidath   +2 more
core   +3 more sources