RNA-binding protein signaling in adult neurogenesis
The process of neurogenesis in the brain, including cell proliferation, differentiation, survival, and maturation, results in the formation of new functional neurons.
Jackie Ngai-Man Chan +6 more
doaj +1 more source
Neurogenesis Drives Stimulus Decorrelation in a Model of the Olfactory Bulb [PDF]
The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory system?
A Arevian +81 more
core +6 more sources
A novel long non-coding natural antisense RNA is a negative regulator of Nos1 gene expression [PDF]
Long non-coding natural antisense transcripts (NATs) are widespread in eukaryotic species. Although recent studies indicate that long NATs are engaged in the regulation of gene expression, the precise functional roles of the vast majority of them are ...
AC Thénié +38 more
core +1 more source
Regulation of neurogenesis by neurotrophins during adulthood: expected and unexpected roles
The subventricular zone (SVZ) of the anterolateral ventricle and the subgranular zone (SGZ) of the hippocampal dentate gyrus are the two main regions of the adult mammalian brain in which neurogenesis is maintained throughout life. Because alterations in
Marçal eVilar, Helena eMira
doaj +1 more source
Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice [PDF]
The hypothalamus is the central regulator of a broad range of homeostatic and instinctive physiological processes, such as the sleep-wake cycle, food intake, and sexually dimorphic behaviors.
Daniel eLee +8 more
core +2 more sources
Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics investigation of neurodevelopmental migratory pathways [PDF]
Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Al-Kaaby, B. +11 more
core +1 more source
Reproduction: A New Venue for Studying Function of Adult Neurogenesis?
Adult neurogenesis has been a focus within the past few years because it is a newly recognized form of neuroplasticity that may play significant roles in behaviors and recovery process after disease.
Benson Wui-Man Lau +2 more
doaj +1 more source
Neurogenesis in the embryonic and adult brain: same regulators, different roles.
Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological stimuli and pathological states.
Noelia eUrban, François eGuillemot
doaj +1 more source
Born to Be Wild: A Case for Targeting Ectopic Adult Born Granule Cells for Seizure Control. [PDF]
[Box: see text]
Corrubia, Lucas, Santhakumar, Viji
core
Roles of microglia in adult hippocampal neurogenesis in depression and their therapeutics
Adult hippocampal neurogenesis generates functional neurons from neural progenitor cells in the hippocampal dentate gyrus (DG) to complement and repair neurons and neural circuits, thus benefiting the treatment of depression.
Shaoyi Fang +14 more
doaj +1 more source

