Results 251 to 260 of about 8,200,615 (297)

Advanced Glycation End Products and Diabetic Retinopathy

open access: yesCurrent Medicinal Chemistry, 2013
Diabetic retinopathy (DR) has a complex pathogenesis which is impacted by a raft of systemic abnormalities and tissue-specific alterations occurring in response to the diabetes milieu. Many pathogenic processes play key roles in retinal damage in diabetic patients.
Chen, M., Curtis, T. M., Stitt, A. W.
openaire   +4 more sources

Advanced glycation end products in uremia

Advances in Renal Replacement Therapy, 2003
The term "advanced glycation end products" (AGEs) stands for a heterogeneous group of amino acid derivatives that are formed via glycation processes between peptide-bound lysine or arginine derivatives and carbonyl compounds, processes originally known from food systems as "Maillard reactions." AGEs accumulate in plasma and tissues with advancing age ...
Thomas, Henle, Toshio, Miyata
openaire   +2 more sources

Advanced glycation and glycoxidation end products in bone

Bone, 2023
Hyperglycemia and oxidative stress, enhanced in diabetes and aging, result in excessive accumulation of advanced glycation and glycoxidation end products (AGEs/AGOEs) in bone. AGEs/AGOES are considered to be "the missing link" in explaining increased skeletal fragility with diabetes, aging, and osteoporosis where increased fracture risk cannot be ...
Bowen, Wang, Deepak, Vashishth
openaire   +2 more sources

Advanced glycation end products and the kidney

American Journal of Physiology-Renal Physiology, 2005
Advanced glycation end products (AGEs) are a heterogeneous group of protein and lipids to which sugar residues are covalently bound. AGE formation is increased in situations with hyperglycemia (e.g., diabetes mellitus) and is also stimulated by oxidative stress, for example in uremia.
Jürgen M, Bohlender   +3 more
openaire   +2 more sources

Advanced Glycation End Products and Diabetic Nephropathy

American Journal of Therapeutics, 2005
Chronic hyperglycemia and oxidative stress in diabetes results in the formation and accumulation advanced glycation end products (AGEs). AGEs have a wide range of chemical, cellular, and tissue effects that contribute to the development of microvascular complications. In particular, AGEs appear to have a key role in the diabetic nephropathy.
Thomas, Merlin C.   +2 more
openaire   +3 more sources

Methods to assess advanced glycation end-products

Current Opinion in Clinical Nutrition & Metabolic Care, 2021
Purpose of review Advanced glycation end-products (AGEs) resulting from protein glycoxidation constitute biomarkers of interest in different pathological situations. Several methods for quantifying AGEs in biological fluids or tissues have been developed without any real consensus on a gold standard method.
Stéphane, Jaisson, Philippe, Gillery
openaire   +2 more sources

Advanced Glycation End Products

2020
Advanced glycation end products (AGEs) play a major role in diabetic vascular complications, such as chronic kidney disease (CKD), by activating pro-oxidant and pro-inflammatory responses. Although traditionally AGEs have been associated with uncontrolled hyperglycemia of diabetes mellitus, there is increasing evidence that exogenous AGEs from diet ...
Annabel Biruete, Jaime Uribarri
openaire   +1 more source

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