Results 81 to 90 of about 9,776,047 (207)

Epigenetic age acceleration and cognitive performance over time in older adults

Alzheimer's & Dementia
This study investigated whether epigenetic age acceleration (AA) is associated with the change in cognitive function and the risk of incident dementia over 9 years, separately in males and females.
Aung Zaw Zaw Phyo, Zimu Wu, Sara E Espinoza, A. Murray, P. Fransquet, J. Wrigglesworth, R. Woods, Joanne Ryan   +7 more
semanticscholar   +1 more source

Age-related differences in correction behavior for unintended acceleration.

PLoS ONE, 2020
Although unintended acceleration caused by pedal misapplication is a cause of traffic accidents, fatal accidents may be avoided if drivers realize their error immediately and quickly correct how they are stepping on the pedal.
Kunihiro Hasegawa, Motohiro Kimura, Yuji Takeda   +2 more
doaj   +1 more source

Race and Ethnicity, Socioeconomic Factors, and Epigenetic Age Acceleration in Survivors of Childhood Cancer

JAMA Network Open
This cross-sectional study analyzes whether associations of epigenetic age acceleration (EAA) with cancer treatment vary by race and ethnicity among survivors of childhood cancer and whether socioeconomic factors mediate the associations.
Cheng Chen, N. Plonski, Q. Dong, Nan Song, Xijun Zhang, Hemang M. Parikh, Emily R. Finch, J. Easton, H. Mulder, Emily Walker, Geoffrey Neale, Yue Pan, Qian Li, Jinghui Zhang, K. Krull, L. Robison, G. Armstrong, Yutaka Yasui, K. Ness, Melissa M. Hudson, Hui Wang, I-Chan Huang, Zhaoming Wang   +22 more
semanticscholar   +1 more source

Systematic underestimation of the epigenetic clock and age acceleration in older subjects

Genome Biology, 2019
Background The Horvath epigenetic clock is widely used. It predicts age quite well from 353 CpG sites in the DNA methylation profile in unknown samples and has been used to calculate “age acceleration” in various tissues and environments.
Louis Y. El Khoury, Tyler Gorrie-Stone, Melissa Smart, Amanda Hughes, Yanchun Bao, Alexandria Andrayas, Joe Burrage, Eilis Hannon, Meena Kumari, Jonathan Mill, Leonard C. Schalkwyk   +10 more
doaj   +1 more source

A multistage theory of age-specific acceleration in human mortality

BMC Biology, 2004
Background Humans die at an increasing rate until late in life, when mortality rates level off. The causes of the late-life mortality plateau have been debated extensively over the past few years. Here, I examine mortality patterns separately for each of
Frank Steven A
doaj   +1 more source

Epigenetic age acceleration in hematopoietic stem cell transplantation

Haematologica
Not available.
Margherita Ursi, Katarzyna Malgorzata Kwiatkowska, Chiara Pirazzini, Gianluca Storci, Daria Messelodi, Salvatore Nicola Bertuccio, Serena De Matteis, Francesco Iannotta, Enrica Tomassini, Marcello Roberto, Maria Naddeo, Noemi Laprovitera, Irene Salamon, Barbara Sinigaglia, Elisa Dan, Francesco De Felice, Francesco Barbato, Enrico Maffini, Sadia Falcioni, Mario Arpinati, Manuela Ferracin, Massimiliano Bonafè, Paolo Garagnani, Francesca Bonifazi   +23 more
doaj   +1 more source

DNA methylation and the epigenetic clock in relation to physical frailty in older people: the Lothian Birth Cohort 1936

Clinical Epigenetics, 2018
Background The biological mechanisms underlying frailty in older people are poorly understood. There is some evidence to suggest that DNA methylation patterns may be altered in frail individuals.
Catharine R. Gale, Riccardo E. Marioni, Sarah E. Harris, John M. Starr, Ian J. Deary   +4 more
doaj   +1 more source

Corrigendum: Novel Zinc-Related Differentially Methylated Regions in Leukocytes of Women With and Without Obesity

Frontiers in Nutrition, 2022
Natália Yumi Noronha, Mariana Barato, Chanachai Sae-Lee, Marcela Augusta de Souza Pinhel, Marcela Augusta de Souza Pinhel, Lígia Moriguchi Watanabe, Vanessa Aparecida Batista Pereira, Guilherme da Silva Rodrigues, Déborah Araújo Morais, Wellington Tavares de Sousa, Vanessa Cristina de Oliveira Souza, Jessica Rodrigues Plaça, Wilson Salgado, Fernando Barbosa, Torsten Plösch, Carla Barbosa Nonino, Carla Barbosa Nonino   +16 more
doaj   +1 more source

Epigenetic age acceleration and allergic diseases: a bidirectional two-sample Mendelian randomization study

Clinical Epigenetics
Objective The epigenetic clock has been regarded as a highly accurate predictor of capturing the complexity between aging and the epigenome. However, there is limited understanding of the epigenetic clock in allergic diseases.
Junfang Sun, Guozhen Fan, Lixin Hu, Zheng Hai Qu, Hong Jiang   +4 more
doaj   +1 more source

Mendelian randomization implicates causal association between epigenetic age acceleration and age-related eye diseases or glaucoma endophenotypes

Clinical Epigenetics
Age-related eye diseases (AREDs) have become increasingly prevalent with the aging population, serving as the leading causes of visual impairment worldwide.
Jiawei Chen, Xiang-Ling Yuan, Xiaoyu Zhou, Jiahao Xu, Xinyue Zhang, Xuanchu Duan   +5 more
semanticscholar   +1 more source