Results 61 to 70 of about 211,860 (282)
p53-sensitive epileptic behavior and inflammation in Ft1 hypomorphic mice [PDF]
, 2018 Epilepsy is a complex clinical condition characterized by repeated spontaneous seizures. Seizures have been linked to multiple drivers including DNA damage accumulation.
Alessandro, Vercelli +10 more
core +2 more sources
Premature aging, allostasis and restorgenesis [PDF]
Spinal Cord, 2013 I feel that the highlight of my research activities is bringing the topic of ‘premature morbidity and aging’ (senectus praecox), in people with spinal cord injury (SCI) and other disabilities, into public awareness ...
openaire +2 more sources
Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad +15 more
wiley +1 more source
Journal of Education, Health and SportIntroduction and Aim. Premature skin aging results from both intrinsic and extrinsic factors, requiring a comprehensive management strategy. This review evaluates current and emerging approaches for preventing and treating premature skin aging, focusing
Anna Ziobro +3 more
doaj +1 more source
Clinical and laboratory criteria for occult form of premature ovarian failure [PDF]
Гинекология, 2018 Purpose of the study. To develop clinical and laboratory criteria characteristic of the occult (hidden) form of premature ovarian failure. Material and methods.
L A Marchenko, R I Mashaeva
doaj +1 more source
Vascular Smooth Muscle-Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome [PDF]
, 2018 Background: Progerin, an aberrant protein that accumulates with age, causes the rare genetic disease Hutchinson-Gilford progeria syndrome (HGPS). Patients who have HGPS exhibit ubiquitous progerin expression, accelerated aging and atherosclerosis, and ...
Andrés Manzano, María J. +7 more
core +4 more sources
Mutations Involved in Premature-Ageing Syndromes
The Application of Clinical Genetics, 2021 Premature-ageing syndromes are a heterogeneous group of rare genetic disorders resembling features of accelerated ageing and resulting from mutations in genes coding for proteins required for nuclear lamina architecture, DNA repair and maintenance of genome stability, mitochondrial function and other cellular processes.
openaire +7 more sources
Arthritis Care &Research, EarlyView.Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús +7 more
wiley +1 more source
On occupational factors and premature aging (literature review)
Сибирский научный медицинский журналQuantitative characteristics of the impact of factors of the production environment (physical, chemical, biological), the severity and intensity of the labor process, their contribution to the deterioration of the health of the working contingent and the
O. A. Savchenko +2 more
doaj +1 more source
The Influence of Different Types of Stress on Psychological Age
Современная зарубежная психология, 2023 The article presents an analysis of modern research on the problem of the impact of stress on the biopsychological age of a person. Understanding the reasons for the increase in biopsychological age is important in the search for ways to slow ...
T.A. Finogenova +3 more
doaj +1 more source