Results 111 to 120 of about 959,384 (214)
In vivo function of NGF/TrkA signaling in the cholinergic neurons of the murine basal forebrain [PDF]
The neurotrophins are a family of secreted proteins that potently regulate diverse neuronal responses. The neurotrophin nerve growth factor (NGF) and its receptors TrkA and p75 are well characterized to control survival, differentiation and function of ...
Mueller, Markus
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Roe deer meat is a prized game product in many European countries. However, concerns exist regarding the accuracy of the amount of declared roe deer in processed game meat foods.
Bukola M. Adenuga +6 more
doaj +1 more source
Padrões de variabilidade do gene ASIP (agouti signaling protein) em mamíferos [PDF]
O melanismo em mamíferos decorre principalmente da atividade de dois genes: MC1R (Melanocortin-1 Receptor), cujo produto induz a produção de eumelanina (pretomarrom); e ASIP (Agouti Signaling Protein), que codifica um peptídeo antagonista que promove a ...
Santos, Daniela Copetti
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Goat agouti gene polymorphism and its association with coat color in indigenous turkish goat breeds
Agouti gene has an important effect on pigment synthesis in mammals. It encodes Agouti signaling protein, which stimulates the phaeomelanin synthesis resulting red, yellow coat color.
Oztabak K., Un C., Gursel F.E., Akis I.
core +1 more source
Molecular characterization of the mouse agouti locus
The agouti locus in mouse chromosome 2 regulates the differential production of eumelanin (black or brown) and phaeomelanin (yellow) pigment granules. Agouti coloration, which is the true wild-type coat color of mice, arises because the individual hair ...
Bultman, Scott Justin
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Agouti-related protein (Agrp), one of the two naturally occurring inverse agonists known to inhibit G protein-coupled receptor activity, regulates energy expenditure by decreasing basal and blocking agonist-promoted melanocortin receptor (MCR) signaling.
Breit, Andreas +5 more
core +1 more source
Transgenerational spermatogenic inheritance of adult male acquired CNS gene expression characteristics has recently been discovered using a Drosophila systems model.
Abhay Sharma
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The melanocortin system is one of the most complex hormonal systems in vertebrates. Atypically, the signaling of melanocortin receptors is regulated by the binding of endogenous antagonists, named agouti-signaling protein (ASIP) and agouti-related ...
Cerdá-Reverter, José Miguel +5 more
core +1 more source
Pharmacological therapies for monogenic obesity caused by MC4R dysfunction
PhDMutations in the melanocortin-4 receptor (MC4R) are the most common cause of monogenic obesity. The majority of MC4R mutations are predicted to cause the receptor to aberrantly fold.
Gooljar, Sakina B
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