Results 61 to 70 of about 98,913 (262)
Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer
Arthritis Care &Research, EarlyView.Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman +7 more
wiley +1 more source
Hepatology, EarlyView., 2022 Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine +4 more
wiley +1 more source
Hepatology, EarlyView., 2022 Visualisation of the study desgin, main results and key findings. Abstract Background and Aims MAFLD often cooccurs with excessive alcohol consumption, while its prognostic value in this group remains unclear. We aimed to study the mortality risk of MAFLD in relation to excessive alcohol consumption and its potential interactions.
Laurens A. van Kleef +2 more
wiley +1 more source
Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR
, 2018 Aryl hydrocarbon receptor (AhR) is a nuclear receptor that controls xenobiotic detoxification via induction of cytochrome P450 1A1 (CYP1A1) and regulates immune responses in the intestine.
Waddah A. Alrefai +5 more
core +2 more sources
Human AHR nucleic acid sequences were obtained from NCBI and primers were designed on Snapgene based on Nhe I and Hind III upstream and downstream digestion sites (Supplementary table 2).
Min Chen (18471864)
core +1 more source
How the AHR Became Important in Cancer: The Role of Chronically Active AHR in Cancer Aggression
, 2020 For decades, the aryl hydrocarbon receptor (AHR) was studied for its role in environmental chemical toxicity i.e., as a quirk of nature and a mediator of unintended consequences of human pollution.
Zhongyan Wang +10 more
core +1 more source
Myb-binding protein 1a augments AhR-dependent gene expression [PDF]
, 2002 We have studied the mechanism by which an acidic domain (amino acids 515-583) of the aromatic hydrocarbon receptor (AhR) transactivates a target gene.
Okino, ST +7 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo +14 more
wiley +1 more source
Aryl Hydrocarbon Receptor (AhR) Signaling in Colonic Cells and Tumors
, 2023 The aryl hydrocarbon receptor (AhR) is overexpressed in many tumor types and exhibits tumor-specific tumor promoter and tumor suppressor-like activity.
Ivan Ivanov +17 more
core +1 more source