Results 121 to 130 of about 10,647 (207)

Inflammatory Signatures Beyond Th1/Th2 Endotypes Provide Insights Into Postoperative Recurrence in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, Volume 16, Issue 11, Page 1269-1279, November 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) represents a spectrum of inflammatory endotypes, driven by distinct T helper (Th) immune responses. The high rate of recurrent disease despite appropriate medical and surgical interventions highlights the need for improved characterization beyond the traditional type 2 and non‐type 2 phenotypes to better
Liyona Kampel, Narin N. Carmel, Shaun Edalati, Hen Chaushu, Forsan Jahshan, Yaniv Hadi, Timur Pestrikov, Leonor Leider Trejo, Nidal Muhanna, Avraham Abergel   +9 more
wiley   +1 more source

Relationship Between Bronchodilator Reversibility and Spirometry Response to Dupilumab in Type 2 High Uncontrolled Severe Asthma

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 253-255, March 2025.
Robert Greig, Kirsten Stewart, Chris RuiWen Kuo, Rory Chan, Brian Lipworth   +4 more
wiley   +1 more source

Efficacy and Predictors of Response to Biologic Therapy and Endoscopic Sinus Surgery in Patients With Nasal Polyps: A Systematic Review

International Forum of Allergy &Rhinology, Volume 16, Issue 11, Page 1342-1351, November 2026.
ABSTRACT Background Biologics and endoscopic sinus surgery (ESS) treat refractory chronic rhinosinusitis with nasal polyposis (CRSwNP), but direct comparisons are lacking. We synthesized efficacy and subgroup data across randomized controlled trials (RCTs) of biologics and ESS.
Arun Chakravorty, Matthew E. Lin, Rory Lubner, Jess C. Mace, Jeffrey Suh, Jivianne Lee, Marilene Wang, Sarah Wise, Naweed Chowdhury, Zachary M. Soler, Justin Turner, Timothy L. Smith, Myung Sim, Daniel M. Beswick   +13 more
wiley   +1 more source

Evaluating the Impact of Prior Sponge and Lavage Sampling on Gene Expression of Nasal CMA1 and TSLP Collected With Brush

Clinical &Experimental Allergy, EarlyView.
Abigail Davis, Sophie Spicer, Lubnaa Hossenbaccus, Anne K. Ellis   +3 more
wiley   +1 more source

Posttranslational Modification Cross‐Talk in Vascular Cells: Molecular Mechanisms and Therapeutic Implications for Atherosclerosis

Cell Biochemistry and Function, Volume 44, Issue 11, November 2026.
ABSTRACT Atherosclerosis is driven by coordinated changes in endothelial cells (ECs), macrophages, and vascular smooth muscle cells (VSMCs). Post‐translational modifications (PTMs), phosphorylation, acetylation, ubiquitination, SUMOylation, O‐GlcNAcylation, palmitoylation, ISGylation, and ADP‐ribosylation, integrate metabolic, inflammatory, and ...
Weiwei Jiang, Haiping Du
wiley   +1 more source

Das proinflammatorische Alarmin S100A8/S100A9 als objektiver Parameter zur Diagnostik eines Peritonsillarabszesses

, 2017
Einleitung: Es wurde untersucht, ob sich das proinflammatorische Alarmin S100A8/S100A9 im Speichel und Serum als objektiver Marker zur Identifizierung eines Peritonsillarabszesses eignet.Methoden: Von Patienten, die sich aufgrund einer akuten ...
Stenner, M, Rudack, C, Vogl, T, Spiekermann, CO, Roth, J   +4 more
core   +1 more source

Benralizumab Inhibits Upper Airway Expression of Thymic Stromal Lymphopoietin in Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Hazel Marriott, Marc Duchesne, Jalal Moolji, Adil Adatia, Subhabrata Moitra, Paige Lacy   +5 more
wiley   +1 more source

Time‐of‐Day Variation in Airway Hyperresponsiveness in Asthma: Potential Circadian Mechanisms and Translational Implications

Clinical and Translational Allergy, Volume 16, Issue 11, November 2026.
Graphical abstract Biological time, time‐dependent airway hyperresponsiveness, and clinical translation. The external day–night cycle entrains the central clock in the suprachiasmatic nucleus and peripheral pulmonary clocks, whereas sleep and activity, posture, environmental exposures, and medication timing modify the airway state observed at a given ...
Chang Zhou, Xinyue Hu, Lijuan Zeng, Yi Tang, Chuxian Yi, Guomin Zhang, Sujuan Peng   +6 more
wiley   +1 more source

Sphingosine‐1‐Phosphate Attenuates LPS‐Induced Inflammatory Cardiac Injury in Association With RASGRP1–S100A9–NLRP3 Signaling

Drug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Lipopolysaccharide (LPS) induces endotoxemia‐associated inflammatory cardiac injury rather than classical viral or autoimmune myocarditis. Sphingosine‐1‐phosphate (S1P) regulates cardiovascular and immune responses, predominantly through S1P receptors, but whether it also modulates macrophage‐associated inflammatory signaling during LPS ...
Chaofu Yue, Qiaolin Li, Chunyan Li, Taoxian Yang, Xian Huang, Feng Yue, Qiuyu Long, Rong Li, Rong Lei, Qingsong Ma, Caimei Hu, Qian Yang, Yongjun Yan, Yuan Liu, QinYong Yan, Mei Yang   +15 more
wiley   +1 more source

The Role of Mitochondrial Homeostasis in the Pathogenesis of Chronic Rhinosinusitis

Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
The vicious cycle between pathogenic factors‐induced inflammation, oxidative stress, and mitochondrial dysfunction in the context of chronic rhinosinusitis. Created in BioRender. Taghizadeh‐Hesary (2026) https://BioRender.com/k5f4t1f. ABSTRACT Background Chronic rhinosinusitis (CRS) is a common clinical condition characterized by persistent ...
Babak Ghalehbaghi, Morteza Fallahpour, Mohammad Nabavi, Maryam Jalessi, Hadi Ghanbari, Nasibeh Khayer, Farzad Taghizadeh‐Hesary   +6 more
wiley   +1 more source