Results 141 to 150 of about 13,748 (218)

Selective Targeting of IL‐1RAP‐Dependent Eosinophilic Inflammation in Allergic Fungal Airway Disease

Allergy, Volume 81, Issue 4, Page 1302-1305, April 2026.
Thomas J. Williams, James S. Griffiths, Luis E. Gonzales‐Huerta, David Bell, Anna K. Reed, Anand Shah, Julian R. Naglik, Darius Armstrong‐James   +7 more
wiley   +1 more source

Multifactorial Causes and Consequences of TLSP Production, Function, and Release in the Asthmatic Airway

Biomolecules
Disruption of the airway epithelium triggers a defensive immune response that begins with the production and release of alarmin cytokines. These epithelial-derived alarmin cytokines, including thymic stromal lymphopoietin (TSLP), are produced in response
Danica L. Brister, Hafsa Omer, Christiane E. Whetstone, Maral Ranjbar, Gail M. Gauvreau   +4 more
doaj   +1 more source

Emerging roles for HMGB1 protein in immunity, inflammation, and cancer

ImmunoTargets and Therapy, 2015
Simona Martinotti, Mauro Patrone, Elia Ranzato DiSIT – Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Alessandria, Italy Abstract: High-mobility group box 1 (HMGB1) protein is a member of the highly conserved ...
Martinotti S, Patrone M, Ranzato E
doaj  

Targeting alarmins to accelerate healing

, 2017
Promoting tissue repair in adults represents a major unmet medical need. Tissue regeneration relies on the activation of quiescent endogenous stem cells and whilst considerable progress has been made, novel therapies based on stem cells have thus far failed to translate to routine clinical practice.
openaire   +1 more source

When Alarmins Are “Therapeutic”

HemaSphere, 2020
openaire   +3 more sources

Blimp-1 integrates alarmin signals in ILC2s and drives proinflammatory functions required for type 2 immunity. [PDF]

J Exp Med
Forster PM, Preußer A, Yano H, Deshpande D, Zhang W, Kowalczyk A, Velleman L, Dubik MO, Uddin J, Emanuel ER, Leclère PS, Mertens R, Gao X, Kofoed-Branzk M, Hauser AE, Mittrücker HW, Diefenbach A, Artis D, Klose CSN.   +18 more
europepmc   +1 more source

Alarmin(g) control [PDF]

Nature Reviews Immunology, 2014
openaire   +1 more source

Editorial: The role of epithelial-derived cytokines in airway disease. [PDF]

Front Allergy
Ortega H, Chung KF.
europepmc   +1 more source

Beyond inflammation: alarmins as critical drivers of pulmonary fibrosis. [PDF]

ERJ Open Res
Pianigiani T, Dilroba A, Gambini C, Hernandez-Gonzalez F, d'Alessandro M, Bergantini L, Sellares J, Bargagli E, Cameli P.   +8 more
europepmc   +1 more source

<i>Klebsiella pneumoniae</i> infection induces an S100A8/A9-mediated autocrine loop in human airway epithelium to amplify inflammation. [PDF]

Front Microbiol
Zheng J, Feng X, Zeng Q, Chen S, Yan C, Huang Z.   +5 more
europepmc   +1 more source