A borrowing hydrogen strategy using an NHC‐Ir(III) catalyst enables selective N‐functionalization of unprotected amino sugars using alcohols as alkylating agents. The use of unprotected substrates avoids extra steps of protection/deprotection, minimizing waste generation.
Aitor Bermejo‐López +7 more
wiley +1 more source
A General Metallaphotoredox Platform for <i>N</i>-Alkylated Sulfoximines as Bioisosteric Building Blocks. [PDF]
Großkopf JJ +3 more
europepmc +1 more source
Strategies for Using Quaternary Ammonium Salts as Alternative Reagents in Alkylations [PDF]
Johanna Templ, Michael Schnürch
openalex +1 more source
Photochemical Allylation of Aldehydes or Alkanes with Vinyl Cyclopropanes
An acylation or alkylation of vinyl cyclopropanes, employing tetra‐n‐butylammonium decatungstate as the photocatalyst, leading allyl ketones or alkenes is presented. A diverse range of substrates were compatible with this protocol, while flow conditions were also developed and mechanistic studies were also performed.
Naya A. Stini, Christoforos G. Kokotos
wiley +1 more source
Analysis of porcine gelatin in gelatin powder and gelatin-containing foods using non-targeted LC-Orbitrap HRMS-based proteomics. [PDF]
Windarsih A +10 more
europepmc +1 more source
Intracellular Catalytic Photooxygenation of α‐Synuclein Amyloid
Amyloid‐selective catalytic photooxygenation reduces amyloid toxicity, aggregation tendencies, and seeding activities. Achieving therapeutic catalysis for intracellular amyloids is challenging due to conflicting oxygenation and reductive cellular environments.
Atsushi Iwai +11 more
wiley +1 more source
Precise N‑Alkylation via Cs-LTA Zeolites: Mechanistic Insights and Green Catalytic Synthesis of High-Yield BBIT through Ion-Exchange Optimization. [PDF]
Yao H +5 more
europepmc +1 more source
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego +4 more
wiley +1 more source
Cu/Pd dual catalyzed stereoselective construction of vicinal tri- and tetrasubstituted stereocenters connected to chiral α-arylacetonitriles. [PDF]
Mimoun L +9 more
europepmc +1 more source

