Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren +7 more
wiley +1 more source
Design and evolution of artificial enzyme with in-situ biosynthesized non-canonical amino acid. [PDF]
Huang W +8 more
europepmc +1 more source
Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
Newcomer to the Calixarene Family: Synthesis and Characterization of Selenacalix[4]arene. [PDF]
Churý M +5 more
europepmc +1 more source
Proteomics of Prostate Cancer Tissue Small Extracellular Vesicles Reveal Alteration of Metabolism
ABSTRACT Prostate cancer (PCa) is a leading male malignancy worldwide, with metabolic reprogramming being a critical hallmark of its progression. Extracellular vesicles (EVs) derived from tissues directly reflect the tumor microenvironment, offering unique insights into cancer pathophysiology that are unattainable through cell line or biofluid‐derived ...
Lijuan Yu +4 more
wiley +1 more source
Overcoming limitations in Chan-Lam amination with alkylboronic esters via aminyl radical substitution. [PDF]
Xiao H, Cao P, Xiong W, Yang T.
europepmc +1 more source
The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Cyclic Tetraindoles with a Cyclooctatetraene Core: Controlling Planarity and Antiaromatic Character via N-Alkylation. [PDF]
Fujimoto K +3 more
europepmc +1 more source
Enantioselektive Cu(I)-katalysierte allylische Substitution mit chiralen Phosphin-Phosphit-Liganden und Anwendung in der Totalsynthese der marinen Naturstoffe Helioporin C und E [PDF]
Lölsberg, Wibke
core
ABSTRACT Rare earth elements (REEs) play an irreplaceable role in modern technology and industry. However, due to the highly similar physicochemical properties among REEs, their separation remains a significant challenge. Additionally, REEs often exist in low‐concentration solutions, making efficient REE recovery an urgent task.
Miao‐Miao Huang +6 more
wiley +1 more source

