Results 281 to 290 of about 253,250 (328)

Correction to 'The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

Iron(III)-Mediated C-H Alkylation: One-Electron Differentiation Increases Activity and Chemoselectivity. [PDF]

J Am Chem Soc
Zhang T, Whitehurst WG, Pecoraro MV, Kim J, Koenig SG, Chirik PJ.   +5 more
europepmc   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Acidity Controlled Formal Nucleophilic Substitution of Hydrofluoroolefin-Based Iodonium Salt with O-nucleophiles: Synthetic Application and Mechanistic Study. [PDF]

Chemistry
Csenki JT, Englert DF, Steinsits D, Fehér PP, Stirling A, Novák Z.   +5 more
europepmc   +1 more source

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

Batch Synthesis of Primaquine Diphosphate Anti-Malarial Drug. [PDF]

Chemistry
Akwi FM, Swartbooi S, Watts P.
europepmc   +1 more source

Intertwined Processes in the Pummerer‐Type Rearrangement Affording α‐Trifluoromethoxylated Thioethers and the Corresponding Highly Enantioenriched Sulfoxides

Chemistry – A European Journal, EarlyView.
Highly stereoenriched α‐trifluoromethoxylated sulfoxides were accessed from racemic aryl methyl sulfoxides, by means of a trifluoromethoxylative Pummerer rearrangement and a highly enantioselective sulfoxidation. The 2‐step procedure could be performed in one pot.
Nicolas Moget, Jérémy Saiter, Fabien Toulgoat, Thierry Billard, Frédéric Leroux, Armen Panossian, Gilles Hanquet   +6 more
wiley   +1 more source

Harnessing Electron Donor-Acceptor Complexes to Improve the Sustainability of the Enantioselective β-Alkylation of Aromatic Enals. [PDF]

ChemSusChem
Di Remigio S, Carboni D, Casagranda G, Marcuzzo L, Casnati F, Zaccheroni N, Lombardo M, Quintavalla A.   +7 more
europepmc   +1 more source

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

Chemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Light-Powered Late-Stage Alkylation of N‑Heteroaromatics in Flow. [PDF]

ACS Cent Sci
Wang S, Zuo Z.
europepmc   +1 more source