Results 81 to 90 of about 6,010 (206)

Psychosocial and menstrual correlates of premenstrual disorders: A community‐based study

International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1472-1479, June 2026.
Abstract Objective To assess the background, psychosocial, and menstrual factors associated with premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) in a community‐based cohort. Methods A prospective cohort study was conducted using data from users of a menstrual tracking application.
Shiori Itoi, Makiko Sampei, Takayuki Tatsumi, Yutaka Osuga, Kaori Koga, Satoshi Narumi, Naho Morisaki   +6 more
wiley   +1 more source

The endogenous cannabinoid system gates plasticity of tonic GABA inhibition

The Journal of Physiology, Volume 604, Issue 12, Page 4984-5010, 15 June 2026.
Abstract figure legend Postsynaptic depolarisation and increases in intracellular Ca2+ ([Ca2+]i) trigger the synthesis of endocannabinoids (eCBs), which are hypothesised to enhance tonic GABAergic inhibition via two primary pathways. In the proposed autocrine mechanism, eCBs activate postsynaptic somatodendritic or mitochondrial CB1 receptors ...
Roberto Colangeli, Fiorenzo Conti
wiley   +1 more source

Allopregnanolone, a GABA-A receptor agonist, decreases gonadotropin levels in women : a preliminary study [PDF]

, 2010
Animal studies suggest regulatory effects on the hypothalamic-pituitary-gonad axis by allopregnanolone, an endogenous gamma-aminobutyric acid A (GABAA) receptor agonist.
Hedström, Helena, Timby, Erika, Bäckström, Torbjörn, Sundström-Poromaa, Inger,, Bäckström, Torbjörn,, Sigrid Nyberg, Helena Hedström, Bixo, Marie, Sundström-Poromaa, Inger, Erika Timby, Torbjörn Bäckström, Marie Bixo, Inger Sundström-Poromaa, Nyberg, Sigrid,, Bixo, Marie,, Nyberg, Sigrid, Timby, Erika,, Hedström, Helena,   +17 more
core   +1 more source

Anti‐apoptotic effects of allopregnanolone on P19 neurons

European Journal of Neuroscience, 2006
AbstractProgesterone and its metabolites are potent allosteric modulators of GABAAreceptor function, through a direct, non‐genomic interaction with specific receptor subtypes. In addition, fluctuations in the concentration of progesterone, and allopregnanolone in particular, have been shown to modulate GABAAreceptor gene expression and activity.
Xilouri, M., Papazafiri, P.
openaire   +3 more sources

GABAergic neuroactive steroids: a new frontier in bipolar disorders?

Behavioral and Brain Functions, 2012
Neurosteroids are synthesized in the brain and modulate brain excitability. There is increasing evidence of their sedative, anesthetic and antiseizure properties, as well as their influence on mood.
Carta Mauro Giovanni, Bhat Krishna M, Preti Antonio   +2 more
doaj   +1 more source

FIGO best practice recommendations for the mental health of women at menopausal age

International Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 588-601, May 2026.
Abstract Mental health during the menopausal transition requires focused attention to ensure supportive experiences for women. This review presents the International Federation of Gynecology and Obstetrics (FIGO) recommendations and summarizes the evidence, addressing 13 key questions framed by members of the FIGO Committee on Women at Menopausal Age ...
Suvarna Khadilkar, Hema Divakar, Chiara Benedetto, Andrea Genazzani, Diana Ramos, Elizabete Argale, Gandhali Deshpande, Martha Hicky, Agnaldo Lopes Da Silva Filho, Enrique Herrera, Milan Balkrishnan   +10 more
wiley   +1 more source

Neuroprotective actions of cerebellar and pineal allopregnanolone on Purkinje cells

FASEB BioAdvances, 2020
The brain produces steroids de novo from cholesterol, so‐called “neurosteroids.” The Purkinje cell, a cerebellar neuron, was discovered as a major site of the biosynthesis of neurosteroids including sex steroids, such as progesterone, from cholesterol in
Kazuyoshi Tsutsui, Shogo Haraguchi
doaj   +1 more source

Gendering the Menstrual Cycle in Behavioral Neuroendocrinology

American Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT The menstrual cycle is increasingly described as a “vital sign of the female body,” with the literature suggesting cycle‐related brain and behavioral changes. With growing interest in the effects that the menstrual cycle has on the brain, body and mind, characterizing what constitutes healthy cycle‐related change has become a central goal of ...
Annie Duchesne, Kiranjot Kaur Jhajj, Nicole White   +2 more
wiley   +1 more source

The Role of Allopregnanolone in Pregnancy in Predicting Postpartum Anxiety Symptoms

Frontiers in Psychology, 2019
Postpartum depression is a serious illness affecting up to 15% of women worldwide after childbirth, and our understanding of its biology is limited. Postpartum anxiety is perhaps more prevalent and less understood.
Lauren M. Osborne, Lauren M. Osborne, Joshua F. Betz, Gayane Yenokyan, Lindsay R. Standeven, Jennifer L. Payne, Jennifer L. Payne   +6 more
doaj   +1 more source

Restoration of Gut Microbiota and Metabolic Homeostasis by Lacticaseibacillus paracasei Zhang in Azithromycin‐Induced Dysbiosis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
This study investigated whether Lacticaseibacillus paracasei Zhang could alleviate the gut microbiota imbalance and its systemic consequences caused by antibiotics. Mice treated with azithromycin exhibited gut microbiota disorders, and subsequent probiotic intervention was carried out.
Xiaoye Liu, Guoqiang Yao, Temuujin Bayarjargal, Lai‐Yu Kwok, Wenyi Zhang   +4 more
wiley   +1 more source