Results 91 to 100 of about 47,878 (245)

A New Approach to Assessing HSV-1 Recombination during Intercellular Spread

Viruses, 2018
The neuroinvasive Herpes simplex virus type 1 (HSV-1) utilizes intergenomic recombination in order to diversify viral populations. Research efforts to assess HSV-1 recombination are often complicated by the use of attenuating mutations, which ...
Gabrielle A. Law, Alix E. Herr, James P. Cwick, Matthew P. Taylor   +3 more
doaj   +1 more source

Tegument Assembly and Secondary Envelopment of Alphaherpesviruses. [PDF]

, 2015
Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their ability to establish lifelong latent infection in neurons. As for all herpesviruses, alphaherpesvirus virions contain a protein-rich layer called "tegument" that ...
Crump, Colin M, Graham, Stephen C, Owen, Danielle J   +2 more
core   +3 more sources

Tethered release of the pseudorabies virus deubiquitinase from the capsid promotes enzymatic activity

Journal of Virology
Herpesviruses carry an assortment of proteins in the interstitial space between the capsid and membrane envelope, collectively referred to as the tegument.
Sarah E. Antinone, John S. Miller, Nicholas J. Huffmaster, Gary E. Pickard, Gregory A. Smith   +4 more
doaj   +1 more source

Decoding the Architecture of the Varicella-Zoster Virus Transcriptome

mBio, 2020
Varicella-zoster virus (VZV), a double-stranded DNA virus, causes varicella, establishes lifelong latency in ganglionic neurons, and reactivates later in life to cause herpes zoster, commonly associated with chronic pain. The VZV genome is densely packed
Shirley E. Braspenning, Tomohiko Sadaoka, Judith Breuer, Georges M. G. M. Verjans, Werner J. D. Ouwendijk, Daniel P. Depledge   +5 more
doaj   +1 more source

Differential cytokine responses following Marek's disease virus infection in chicken genotypes differing in resistance to Marek's disease [PDF]

, 2003
The production of cytokine mRNAs, in addition to viral DNA, was quantified by real-time quantitative reverse transcription-PCR (RT-PCR) (cytokines) or PCR (virus) in splenocytes during the course of Marek's disease virus (MDV) infection in four inbred ...
Davison, T F, Kaiser, Pete, Underwood, G
core   +1 more source

Varicella‐Zoster Virus‐Specific Cell‐Mediated Immune Response Kinetics and Latent Viral Load Depending on Aging

Journal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Herpes zoster (HZ), an infection caused by varicella‐zoster virus (VZV) reactivation, results from an age‐related decline in VZV‐specific cell‐mediated immunity (CMI). Digital droplet PCR (ddPCR) precisely quantifies latent VZV DNA in the blood, a potential biomarker of subclinical viral reactivation and its association with HZ risk.
Hyo‐Ju Son, Seung‐Beom Kim, Ji‐Soo Kwon, Kyung Hwa Jung, Sang‐Oh Lee, Sung‐Han Kim   +5 more
wiley   +1 more source

Alphaherpesvirus in Pets and Livestock

Microorganisms
Herpesviruses are a group of DNA viruses capable of infecting multiple mammalian species, including humans. This review primarily summarizes four common alphaherpesviruses found in pets and livestock (feline, swine, canine, and bovine) in aspects such as epidemiology, immune evasion, and latency and reactivation.
Shu-Hui Duan, Ze-Min Li, Xue-Jie Yu, Dan Li   +3 more
openaire   +2 more sources

Sequence of the ateline alphaherpesvirus 1 (HVA1) genome [PDF]

Archives of Virology, 2017
Here, we report the genome sequence of a spider monkey alphaherpesvirus (ateline alphaherpesvirus 1, HVA1) and compare it with that of other primate alphaherpesviruses. The HVA1 genome is 147,346 bp long and contains 67 predicted ORFs. The genetic layout of the HVA1 genome is similar to that of the squirrel monkey alphaherpesvirus (saimirine ...
R. Eberle, Darla H. Black
openaire   +2 more sources

Distinct NK Cell Genetic Variants Are Associated With HSV‐2 Versus VZV Infection of the CNS

Journal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Human alphaherpesvirus infections may cause life‐threatening CNS disease. As NK cell responses are crucial for herpesvirus control, we assessed if specific human genetic variants with influence on host NK cell functions are associated with HSV‐2 or VZV CNS disease development.
Marianne Graninger, Laura Maria Kühner, Sarah Maria Berger, Hannes Vietzen, Elisabeth Puchhammer‐Stöckl   +4 more
wiley   +1 more source

Systemic equid alphaherpesvirus 9 in a Grant’s zebra [PDF]

Journal of Veterinary Diagnostic Investigation, 2018
A 2-y-old female Grant’s zebra ( Equus quagga [ burchellii] boehmi) was presented with a clinical history of depression, anorexia, and weakness of 1-wk duration. Postmortem examination identified ulcers on the tongue and palate; a large abscess adjacent to the larynx; left lung consolidation; mild swelling, darkening, and congestion of the liver with ...
Moeller, Robert B, Crossley, Beate, Pipkin, Arlena, Li, Yanqiu, Balasuriya, Udeni BR   +4 more
openaire   +4 more sources