Results 71 to 80 of about 47,279 (194)

Different outcomes of Canid alphaherpesvirus 1 infection in a litter of puppies: The silent viral spread [PDF]

, 2022
Canid alphaherpesvirus 1 causes worldwide infection with different outcomes in neonatal puppies and adults, followed by latency. Here, we report the varied outcomes of Canid alphaherpesvirus 1 infection in a Dalmatian litter of 12 puppies in Italy.
Nicola Decaro, Troisi, Alessandro, Gallo, Ilaria, Alessandro Troisi, Maria Luisa Marenzoni, Marenzoni, Maria Luisa, Ilaria Gallo, Sylla, Lakamy, Decaro, Nicola, Lakamy Sylla   +9 more
core   +1 more source

Isolation and Characterization of a Novel Alphaherpesvirus in Fruit Bats [PDF]

Journal of Virology, 2014
ABSTRACT Bats are known to harbor emerging RNA viruses. Recent studies have used high-throughput sequencing technology to identify various virus species, including DNA viruses that are harbored by bats; however, little is known about the nature of these potentially novel viruses.
Sasaki, Michihito, Setiyono, Agus, Handharyani, Ekowati, Kobayashi, Shintaro, Rahmadani, Ibenu, Taha, Siswatiana, Adiani, Sri, Subangkit, Mawar, Nakamura, Ichiro, Sawa, Hirofumi, Kimura, Takashi, Hutt-Fletcher, L.   +11 more
openaire   +3 more sources

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection Against Pseudorabies Virus

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Examining the Role of Transmission of Chelonid Alphaherpesvirus 5 [PDF]

EcoHealth, 2017
Marine turtle fibropapillomatosis (FP) is a devastating neoplastic disease characterized by single or multiple cutaneous and visceral fibrovascular tumors. Chelonid alphaherpesvirus 5 (ChHV5) has been identified as the most likely etiologic agent. From 2010 to 2013, the presence of ChHV5 DNA was determined in apparently normal skin, tumors and swab ...
Chaves, Andrea, Aguirre, A. Alonso, Blanco-Peña, Kinndle, Moreira Soto, Andrés, Monge, Otto, Torres, Ana M., Soto-Rivas, José L., Lu, Yuanan, Chacón, Didiher, Fonseca, Luis, Jiménez, Mauricio, Gutierrez-Espeleta, Gustavo A., Lierz, Michael   +12 more
openaire   +4 more sources

The Role of VP16 in the Life Cycle of Alphaherpesviruses

Frontiers in Microbiology, 2020
The protein encoded by the UL48 gene of alphaherpesviruses is named VP16 or alpha-gene-transactivating factor (α-TIF). In the early stage of viral replication, VP16 is an important transactivator that can activate the transcription of viral immediate ...
Dengjian Fan, Dengjian Fan, Dengjian Fan, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Renyong Jia, Renyong Jia, Renyong Jia, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Dekang Zhu, Dekang Zhu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Xumin Ou, Xumin Ou, Xumin Ou, Sai Mao, Sai Mao, Sai Mao, Qun Gao, Qun Gao, Qun Gao, Di Sun, Di Sun, Di Sun, Xingjian Wen, Xingjian Wen, Xingjian Wen, Yunya Liu, Yunya Liu, Yunya Liu, Yanling Yu, Yanling Yu, Yanling Yu, Ling Zhang, Ling Zhang, Ling Zhang, Bin Tian, Bin Tian, Leichang Pan, Leichang Pan, Xiaoyue Chen, Xiaoyue Chen, Xiaoyue Chen   +62 more
doaj   +1 more source

Suspected lymphoid leukosis visceral lymphoma with intestinal and ovarian involvement in a chicken

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract An adult hen from a small poultry flock was submitted for diagnostic investigation because of nonspecific clinical disease and suspected neoplasia. At necropsy, the bird had ascites, splenomegaly, severe intestinal adhesions, nodular intestinal lesions and ovarian masses. Histopathology revealed extensive infiltration of the intestinal mucosa,
Thomas Salles Dias, Taís da Silva Lopes Chagas, Davi Lemos Monteiro, Carlos Henrique Campello Costa, Aniesse Siva Aguiar, Dayse Lima da Costa Abreu   +5 more
wiley   +1 more source

Alphaherpesvirus: isolation, identification, partial characterisation, associated pathologic findings, and epidemiology in beluga whales (Delphinapterus leucas) in Alaska and Arctic Canada

Arctic Science, 2018
Live, dead stranded, and harvested belugas (Delphinapterus leucas) in Alaska and the western Canadian Arctic were screened for viruses utilizing a primary beluga cell line. Samples consisted of swabs from blowhole, anus, and genital tract.
Ole Nielsen, Kathleen A. Burek-Huntington, Lisa L. Loseto, Maria Morell, Carlos H. Romero   +4 more
doaj   +1 more source

Equine Alphaherpesviruses Require Activation of the Small GTPases Rac1 and Cdc42 for Intracellular Transport

Microorganisms, 2020
Viruses utilize host cell signaling to facilitate productive infection. Equine herpesvirus type 1 (EHV-1) has been shown to activate Ca2+ release and phospholipase C upon contact with α4β1 integrins on the cell surface.
Oleksandr Kolyvushko, Maximilian A. Kelch, Nikolaus Osterrieder, Walid Azab   +3 more
doaj   +1 more source

CD49a expression defines a metabolically robust, cytokine‐biased liver NK cell subset in rhesus macaques during lentivirus infection

Immunology &Cell Biology, Volume 104, Issue 7, Page 656-666, August 2026.
Liver‐resident NK cells (CD49a+ NK cells) in rhesus macaques display distinct activating receptor and metabolic markers enhanced phenotype compared with hepatic NK cell subsets (CD49a−) in the liver. These cells exhibit heightened cytokine polyfunctionality with restrained cytotoxic responses upon mitogen stimulation in comparison with CD49a− NK cell ...
Andrew Hudson, Melissa Xin Yu Wong, Michael Verdolin, R Keith Reeves, Cordelia Manickam   +4 more
wiley   +1 more source

The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression

Journal of Virology
Alpha-ketoglutarate-dependent dioxygenase, also known as fat mass and obesity-associated protein (FTO), is an RNA demethylase that mediates the demethylation of N6,2-O-dimethyladenosine (m6Am) and N6-methyladenosine (m6A). Both m6Am and m6A are prevalent
Ruth Verhamme, Robert J. J. Jansens, Jianheng Liu, Fien Van Raemdonck, Cliff Van Waesberghe, Luke Nicholson, Samie R. Jaffrey, Herman W. Favoreel   +7 more
doaj   +1 more source