Results 71 to 80 of about 44,477 (170)

Exploring the Antiviral Potential of Tungsten Oxide Nanoparticles Against Herpes Simplex Virus Type 1: A Promising Alternative to Acyclovir

open access: yesIET Nanobiotechnology, Volume 2026, Issue 1, 2026.
Herpes simplex virus type 1 (HSV‐1) is responsible for the majority of cold sores, herpetic keratitis‐induced blindness, profound skin lesions, and encephalitis that can be fatal. Currently, acyclovir and its derivatives are the first‐line therapy for the treatment of HSV‐1 infection.
Abdulhussain Kadhim Jwaziri   +7 more
wiley   +1 more source

A New Approach to Assessing HSV-1 Recombination during Intercellular Spread

open access: yesViruses, 2018
The neuroinvasive Herpes simplex virus type 1 (HSV-1) utilizes intergenomic recombination in order to diversify viral populations. Research efforts to assess HSV-1 recombination are often complicated by the use of attenuating mutations, which ...
Gabrielle A. Law   +3 more
doaj   +1 more source

Structural Insights Into the Nuclear Import of Marek’s Disease Virus Large Tegument Protein

open access: yesAdvances in Virology, Volume 2026, Issue 1, 2026.
Marek’s disease (MD) is a highly contagious neoplastic disorder of poultry caused by MD virus (MDV; gallid alphaherpesvirus 2 [GaAHV2]). Infection results in profound immunosuppression, neurological dysfunction, and the development of malignant T‐cell lymphomas.
Babu Kanti Nath   +7 more
wiley   +1 more source

Decoding the Architecture of the Varicella-Zoster Virus Transcriptome

open access: yesmBio, 2020
Varicella-zoster virus (VZV), a double-stranded DNA virus, causes varicella, establishes lifelong latency in ganglionic neurons, and reactivates later in life to cause herpes zoster, commonly associated with chronic pain. The VZV genome is densely packed
Shirley E. Braspenning   +5 more
doaj   +1 more source

Assessing Nanopore Targeted Sequencing for the Diagnosis of Pulmonary Infections: A Comparative Multidisease Approach

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Pulmonary infections remain a significant global health burden, particularly in immunocompromised individuals and patients with chronic respiratory or systemic diseases. Conventional microbiological tests (CMTs), though widely used, often have limited sensitivity and delayed results, especially in polymicrobial or atypical infections.
Ying Zhao   +7 more
wiley   +1 more source

Varicella–Zoster Virus Reactivation Presenting as Cranial Neuritis Without Rash in Late Pregnancy: A Case Report

open access: yesCase Reports in Obstetrics and Gynecology, Volume 2026, Issue 1, 2026.
Introduction Neurological complications of reactivated varicella–zoster virus (VZV) are uncommon in immunocompetent individuals and are rarely reported during pregnancy. VZV reactivation may cause cranial neuritis, including Ramsay Hunt syndrome, or may present without cutaneous lesions as zoster sine herpete, complicating diagnosis.
Renata Košir Pogačnik   +4 more
wiley   +1 more source

Systemic equid alphaherpesvirus 9 in a Grant’s zebra [PDF]

open access: yesJournal of Veterinary Diagnostic Investigation, 2018
A 2-y-old female Grant’s zebra ( Equus quagga [ burchellii] boehmi) was presented with a clinical history of depression, anorexia, and weakness of 1-wk duration. Postmortem examination identified ulcers on the tongue and palate; a large abscess adjacent to the larynx; left lung consolidation; mild swelling, darkening, and congestion of the liver with ...
Moeller, Robert B   +4 more
openaire   +4 more sources

Towards Integrated Surveillance of Marine Brucellosis: Diagnostic and Phylogenetic Assessment of Brucella ceti in Stranded Dolphins of the Western Mediterranean Sea

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Reports of brucellosis in free‐ranging cetaceans are increasing worldwide, particularly in the Mediterranean Sea. To enhance diagnostic accuracy and epidemiological understanding of cetacean brucellosis in the Western Mediterranean Sea, we analyzed bacteriological, serological, and molecular data from 30 cetaceans belonging to three different species ...
Ignacio Vargas-Castro   +15 more
wiley   +1 more source

Detection and Genomic Characterization of Novel Respiratory Viruses in US and Mexican Cattle Farms

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Respiratory virus infections in cattle cause an estimated more than $1 billion in production losses and can threaten human health. During February 2024 to May 2025, we employed a One Health approach to surveil for respiratory viruses among cattle, farm workers, and environmental samples from 11 US and Mexican beef or dairy cattle farms.
Judith U. Oguzie   +16 more
wiley   +1 more source

Directional Spread of Alphaherpesviruses in the Nervous System

open access: yesViruses, 2013
Alphaherpesviruses are pathogens that invade the nervous systems of their mammalian hosts. Directional spread of infection in the nervous system is a key component of the viral lifecycle and is critical for the onset of alphaherpesvirus-related diseases.
Lynn W. Enquist, Tal Kramer
doaj   +1 more source

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