Results 41 to 50 of about 3,257,979 (198)
Bat Dicer antiviral role and subcellular localization differ upon alphavirus infection in two distinct species. [PDF]
PLoS PathogGaucherand L +3 more
europepmc +2 more sources
Death and gastrointestinal bleeding complicate encephalomyelitis in mice with delayed appearance of CNS IgM after intranasal alphavirus infection. [PDF]
J Gen Virol, 2018 Baxter VK +4 more
europepmc +3 more sources
Arthritogenic Alphavirus Capsid Protein
Life, 2021 In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial
Shambhavi Rao, Adam Taylor
doaj +1 more source
Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus
mSphere, 2021 Mouse models that accurately replicate the immunopathogenesis and clinical disease of alphavirus infection are vital to the preclinical development of therapeutic strategies that target alphavirus infection and disease.
Eranga Abeyratne +6 more
doaj +1 more source
Early Events in Alphavirus Replication Determine the Outcome of Infection [PDF]
Journal of Virology, 2012 ABSTRACT Alphaviruses are a group of important human and animal pathogens. They efficiently replicate to high titers in vivo and in many commonly used cell lines of vertebrate origin. They have also evolved effective means of interfering with development of the innate immune
Ilya Frolov +4 more
openalex +3 more sources
BHK-21 Cell Clones Differ in Chikungunya Virus Infection and MXRA8 Receptor Expression
Viruses, 2021 Baby hamster kidney-21 (BHK-21) cells are widely used to propagate and study many animal viruses using infection and transfection techniques. Among various BHK-21 cell clones, the fibroblast-like BHK-21/C-13 line and the epithelial-like BHK-21/WI-2 line ...
Peiqi Yin, Margaret Kielian
doaj +1 more source
Cells, 2021 Alphaviruses are a group of arboviruses that generate chronic inflammatory rheumatisms in humans. Currently, no approved vaccines or antiviral therapies are available to prevent or treat alphavirus-induced diseases.
Anthony Dobi +3 more
doaj +1 more source
Effect of alphavirus infection on mouse embryos [PDF]
Infection and Immunity, 1982 Seven strains and mutants of the alphaviruses, Semliki Forest virus and Sindbis virus, differed in their lethality for mouse embryos and their mothers. The A7 strain and the neurovirulence mutant M103 of Semliki Forest virus were selected for detailed comparison. A7 produced 100% lethality of mouse embryos but was avirulent for their mothers.
Atkins, G J, Carter, J, Sheahan, B J
openaire +2 more sources
The Regulation of Translation in Alphavirus-Infected Cells [PDF]
Viruses, 2018 Sindbis virus (SINV) contains an RNA genome of positive polarity with two open reading frames (ORFs). The first ORF is translated from the genomic RNA (gRNA), rendering the viral non-structural proteins, whereas the second ORF is translated from a subgenomic mRNA (sgRNA), which directs the synthesis of viral structural proteins. SINV infection strongly
Luis Carrasco +2 more
openaire +4 more sources
Sequelae and Animal Modeling of Encephalitic Alphavirus Infections
Viruses, 2023 Eastern (EEEV), Venezuelan (VEEV), and western equine encephalitis viruses (WEEV) are members of the genus Alphavirus, family Togaviridae. Typically spread by mosquitoes, EEEV, VEEV, and WEEV induce febrile illness that may develop into more severe encephalitic disease, resulting in myriad severe neurologic sequelae for which there are no vaccines or ...
Rachel A. Reyna, Scott C. Weaver
openaire +3 more sources