Results 71 to 80 of about 17,945 (225)

Wolbachia and arbovirus inhibition in mosquitoes [PDF]

, 2013
Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
core   +1 more source

An All‐in‐One Metabarcoding Approach to Mosquito and Arbovirus Xenosurveillance

Molecular Ecology Resources, EarlyView.
ABSTRACT Next‐generation sequencing (NGS) has the potential to transform mosquito‐borne disease surveillance but remains under‐utilised. This study introduces a comprehensive multi‐loci metabarcoding‐based MX (molecular xenomonitoring) approach to mosquito and arbovirus surveillance, enabling parallel identification of mosquito vectors, circulating ...
Brian J. Johnson, Melissa C. Graham, Elina Panahi, Carla Julia S. P. Vieira, Nisa Suraj Nath, Paul Mason, Jamie Gleadhill, Darran Thomas, Michael B. Onn, Martin A. Shivas, Damien Shearman, Jonathan M. Darbro, Gregor J. Devine   +12 more
wiley   +1 more source

Alphavirus Infection of the CNS: Entry, Dissemination, and Neurodegeneration

European Journal of Molecular & Clinical Medicine, 2015
Alphaviruses most often associated with neuroinvasive disease are limited to the Americas and include strains of EEEV, VEEV, and WEEV. The process of alphavirus entry into the CNS of infected vertebrates following challenge is not well-understood. It is thought that virus entry into the CNS depends on the inoculation route.
Ken E. Olson, Amber B. Rico, Tawfik A. Aboellail, Aaron T. Phillips   +3 more
openaire   +2 more sources

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel, Delgui, Laura Ruth   +1 more
core   +2 more sources

Borna disease virus infection: Retrospective case series of five horses and two donkeys in Switzerland

Equine Veterinary Education, EarlyView.
Summary Borna disease is an acute to subacute, rarely chronic non‐purulent meningoencephaylomyelitis affecting mainly horses and sheep. This case series describes the clinical signs, diagnosis, treatment, outcome and post‐mortem findings of five horses and two donkeys with this condition. The equids affected were geldings or mares of various breeds and
I. L. Piotrowski, M. Hilbe, H. K. Junge
wiley   +1 more source

Characterization of an In Vitro Model of Alphavirus Infection of Immature and Mature Neurons [PDF]

Journal of Virology, 2005
ABSTRACT Terminally differentiated, mature neurons are essential cells that are not easily regenerated. Neurotropic viruses, such as Sindbis virus (SV), cause encephalomyelitis through their ability to replicate in neurons. SV causes the death of immature neurons, while mature neurons can often survive infection.
Diane E. Griffin, Patty S. Vernon
openaire   +3 more sources

Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions [PDF]

, 1985
We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome.
Franke, Christine A., Hruby, Dennis E., Rice, Charles M., Strauss, James H.   +3 more
core  

Betanodavirus Quantification and IFN I‐Antagonism Detection Using Luciferase Reporter Systems Based on Fish mx Promoters

Journal of Fish Diseases, EarlyView.
ABSTRACT Mx genes display strong and quick induction in response to viral infections, which varies according to the viral virulence; furthermore, mx transcription is blocked by several viruses as part of their immune evasion strategies. Therefore, the level and time course of mx induction reflect virus–host interplay. This idea prompted the development
Daniel Álvarez‐Torres, Patricia Moreno, Esther García‐Rosado, M. Carmen Alonso, Julia Béjar   +4 more
wiley   +1 more source

Controlled Field Trial of Pancreas Disease Vaccines in Farmed Atlantic Salmon: Effects on Growth and Mortality During a SAV2 Outbreak

Journal of Fish Diseases, EarlyView.
ABSTRACT Pancreas disease (PD), caused by salmonid alphavirus (SAV), is a concern for salmon aquaculture in Scotland, Ireland and Norway. This article presents results from a controlled field trial monitoring three study groups from vaccination to harvest.
Jostein Mulder Pettersen, Marte Follesø Sønnervik, Marius Karlsen, Hege Jørstad Sekkenes, Geir Schriwer, Petter Gjesdal, Ane Sandtrø, Magnus Vikan Røsæg   +7 more
wiley   +1 more source

Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis. [PDF]

, 1998
Recent studies have established cell type- specific, proapoptotic, or antiapoptotic functions for the transcription factor NF-kappaB. In each of these studies, inhibitors of NF-kappaB activity have been present before the apoptotic stimulus, and so the ...
DiDonato, JA, Hardwick, JM, Hoffmann, A, Lin, KI, Ratan, RR   +4 more
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