Results 101 to 110 of about 15,705 (275)
APMIS, Volume 133, Issue 12, December 2025.ABSTRACT RNA hairpins may constitute a foundation of genetic evolution both in viruses and other organisms. Stem‐loops theoretically comprise a stable part, the double‐stranded stem, and a single‐stranded loop allowing evolution. Here we tested for SARS‐CoV‐2 if “fertile” mutations were in loops while mutations in stems were poorly tolerated and rarely
Philippe Colson +5 more
wiley +1 more source
Viruses, 2014 Alphavirus vectors have demonstrated high levels of transient heterologous gene expression both in vitro and in vivo and, therefore, possess attractive features for vaccine development.
Kenneth Lundstrom
doaj +1 more source
Semliki Forest viiruse replikaasivalgu nsP1 uurimine [PDF]
, 2013 Väitekirja elektrooniline versioon ei sisalda publikatsioone.Semliki Forest viirus kuulub alfaviiruste perekonda sugukonnas Togaviridae. Alfaviirused on olulised patogeenid ning põhjustavad erinevaid vaevusi nii loomadele kui ka inimestele.
Karo-Astover, Liis
core
Why enveloped viruses need cores -- the contribution of a nucleocapsid core to viral budding
, 2017 During the alphavirus lifecycle, a nucleocapsid core buds through the cell membrane to acquire an outer envelope of lipid membrane and viral glycoproteins. However, the presence of a nucleocapsid core is not required for assembly of infectious particles.
Hagan, Michael F. +2 more
core +1 more source
Mutations in the E2 glycoprotein and the 3\u27 untranslated region enhance chikungunya virus virulence in mice [PDF]
, 2017 Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection.
Carpentier, Kathryn S +8 more
core +3 more sources
Journal of Fish Diseases, Volume 48, Issue 12, December 2025.ABSTRACT Mx genes display strong and quick induction in response to viral infections, which varies according to the viral virulence; furthermore, mx transcription is blocked by several viruses as part of their immune evasion strategies. Therefore, the level and time course of mx induction reflect virus–host interplay. This idea prompted the development
Daniel Álvarez‐Torres +4 more
wiley +1 more source
A customized program for the identification of conserved protein sequence motifs
BioTechniques, 2020 We searched for viral protein sequences that could be important for tissue tropism. To achieve this goal, human pathogenic viruses were classified according to the tissue they infect (e.g., pulmonary), irrespective of whether they were enveloped or non ...
Mohammad Mian +7 more
doaj +1 more source
Evolutionary Relationships and Systematics of the Alphaviruses [PDF]
Journal of Virology, 2001 ABSTRACT Partial E1 envelope glycoprotein gene sequences and complete structural polyprotein sequences were used to compare divergence and construct phylogenetic trees for the genus Alphavirus . Tree topologies indicated that the mosquito-borne alphaviruses could have arisen in either the Old or the New ...
Powers, Ann M. +6 more
openaire +3 more sources
Journal of Fish Diseases, Volume 48, Issue 12, December 2025.ABSTRACT Pancreas disease (PD), caused by salmonid alphavirus (SAV), is a concern for salmon aquaculture in Scotland, Ireland and Norway. This article presents results from a controlled field trial monitoring three study groups from vaccination to harvest.
Jostein Mulder Pettersen +7 more
wiley +1 more source
Human and murine IFIT1 proteins do not restrict infection of negative-sense RNA viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae families [PDF]
, 2015 UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses.
Amarasinghe, Gaya +12 more
core +3 more sources