Results 101 to 110 of about 15,327 (237)
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Small Science, Volume 6, Issue 1, January 2026.Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
A customized program for the identification of conserved protein sequence motifs
BioTechniques, 2020 We searched for viral protein sequences that could be important for tissue tropism. To achieve this goal, human pathogenic viruses were classified according to the tissue they infect (e.g., pulmonary), irrespective of whether they were enveloped or non ...
Mohammad Mian +7 more
doaj +1 more source
Genome-wide RNAi screen identifies novel host proteins required for alphavirus entry. [PDF]
PLoS Pathogens, 2013 The enveloped alphaviruses include important and emerging human pathogens such as Chikungunya virus and Eastern equine encephalitis virus. Alphaviruses enter cells by clathrin-mediated endocytosis, and exit by budding from the plasma membrane.
Yaw Shin Ooi +4 more
doaj +1 more source
Mutations in the E2 glycoprotein and the 3\u27 untranslated region enhance chikungunya virus virulence in mice [PDF]
, 2017 Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection.
Carpentier, Kathryn S +8 more
core +3 more sources
Negeviruses Reduce Replication of Alphaviruses during Coinfection
bioRxiv, 2020 Negeviruses are a group of insect-specific viruses (ISVs), viruses known to infect only insects. They have been discovered over a wide geographical and species range. ABSTRACT Negeviruses are a group of insect-specific viruses (ISVs) that have been found
Edward I. Patterson +6 more
semanticscholar +1 more source
Journal of Fish Diseases, Volume 49, Issue 1, January 2026.ABSTRACT Columnaris‐causing bacteria (CCB) represent a group of four Flavobacterium species, previously classified under Flavobacterium columnaris, causing a threatening condition in salmonid farming characterised by cutaneous and gill lesions, commonly referred to as ‘saddleback disease’. A peracute skin disease outbreak with high mortality in rainbow
Samuele Zamparo +11 more
wiley +1 more source
Journal of Virology, 2020 Old World alphaviruses comprise several medically relevant viruses, including chikungunya virus and Ross River virus. Recurrent outbreaks and the lack of antivirals and vaccines demand ongoing research to fight the emergence of these infectious diseases.
Benjamin Götte +4 more
semanticscholar +1 more source
Global Warming Affects the Pathogenesis of Important Fish Diseases in European Aquaculture
Reviews in Aquaculture, Volume 18, Issue 1, January 2026.The effect of global warming on pathogens and their fish hosts that could exacerbate the negative outcomes for aquaculture. Changes in farming practices and the development of innovative mitigation tools may prove essential to cope with the effects and impacts of rising water temperatures on fish diseases in Europe.
George Rigos +7 more
wiley +1 more source
Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry
Viruses, 2019 Viruses are a major threat to human health and economic well-being. In recent years Ebola, Zika, influenza, and chikungunya virus epidemics have raised awareness that infections can spread rapidly before vaccines or specific antagonists can be made ...
Michela Mazzon +17 more
doaj +1 more source
Small RNA analysis in Sindbis virus infected human HEK293 cells [PDF]
, 2013 In contrast to the defence mechanism of RNA interference (RNAi) in plants and invertebrates, its role in the innate response to virus infection of mammals is a matter of debate.
A Chakrabarti +61 more
core +3 more sources