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Memorandum / Arbeitsgruppe Alternative Wirtschaftpolitik

MEMORANDUM / ARBEITSGRUPPE ALTERNATIVE WIRTSCHAFTPOLITIK Memorandum / Arbeitsgruppe Alternative Wirtschaftpolitik Memorandum, Alternativen der Wirtschaftspolitik / Arbeitsgruppe "Alternative ...
Arbeitsgruppe Alternative Wirtschaftspolitik
core   +1 more source

The coral Acropora loripes genome reveals an alternative pathway for cysteine biosynthesis in animals. [PDF]

Sci Adv, 2022
Salazar OR, N Arun P, Cui G, Bay LK, van Oppen MJH, Webster NS, Aranda M.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Deficiencias de los componentes de las vías de activación clásica y alternativa del sistema del complemento Deficiencies of the components of the classic and alternative activation pathways of the complement system

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2006
Las deficiencias congénitas de los componentes individuales de las vías clásica y alternativa del sistema del complemento, dan lugar a un conjunto de enfermedades de frecuencia relativamente baja. Las personas con deficiencias en estas funciones muestran
Yanelkys Cos Padrón, Vianed Marsán Suárez, Rinaldo Villaescusa Blanco, Consuelo Macías Abraham   +3 more
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Type 2 and type 1 diabetes have opposing effects on the systemic murine complement alternative pathway. [PDF]

iScience
Colineau L, Kolodziej O, Ajona D, Pio R, Blom AM, King BC.   +5 more
europepmc   +1 more source

Regulatable Complement Inhibition of the Alternative Pathway Mitigates Wet Age-Related Macular Degeneration Pathology in a Mouse Model. [PDF]

Transl Vis Sci Technol, 2023
Parsons NB, Annamalai B, Rohrer B.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Alternative

, 2017
Unconventional, uncommon, irregular, off-beat, counter to as in contradistinction to the popular. Here we look to the margins of film and media, practice and industry to explore alternative approaches to popular modes of thinking and doing. The theme of ‘
Grady Hancock (13073166)
core