SAR443809: a selective inhibitor of the complement alternative pathway, targeting complement factor Bb. [PDF]
Blood Adv, 2023 Rajagopal V +12 more
europepmc +1 more source
What should a robot learn from an infant? Mechanisms of action interpretation and observational learning in infancy [PDF]
, 2003 The paper provides a summary of our recent research on preverbal infants (using violation-of-expectation and observational learning paradigms) demonstrating that one-year-olds interpret and draw systematic inferences about other’s goal-directed actions ...
Gergely, György
core
NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis [PDF]
, 2015 Layla Boutaffala +19 more
openalex +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Heme Interactions as Regulators of the Alternative Pathway Complement Responses and Implications for Heme-Associated Pathologies. [PDF]
Curr Issues Mol Biol, 2023 Tsiftsoglou SA.
europepmc +1 more source
Dissociation of Action and Object Naming: Evidence From Cortical Stimulation Mapping [PDF]
, 2005 This cortical stimulation mapping study investigates the neural representation of action and object naming. Data from 13 neurosurgical subjects undergoing awake cortical mapping is presented.
Brinkley, James F +5 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Hypothesis Regarding the Pathophysiological Role of Alternative Pathways of Angiotensin II Formation in Atherosclerosis [PDF]
, 2000 Kikuo Arakawa, Hidenori Urata
openalex +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The Factor H protein family: The switchers of the complement alternative pathway. [PDF]
Immunol Rev, 2023 Lucientes-Continente L +2 more
europepmc +1 more source